Results 31 to 40 of about 9,181,201 (335)

Investigating Conversion from Mild Cognitive Impairment to Alzheimer's Disease using Latent Space Manipulation [PDF]

open access: yesarXiv, 2021
Alzheimer's disease is the most common cause of dementia that affects millions of lives worldwide. Investigating the underlying causes and risk factors of Alzheimer's disease is essential to prevent its progression. Mild Cognitive Impairment (MCI) is considered an intermediate stage before Alzheimer's disease.
arxiv  

Comprehensive Review on Alzheimer’s Disease: Causes and Treatment

open access: yesMolecules, 2020
Alzheimer’s disease (AD) is a disorder that causes degeneration of the cells in the brain and it is the main cause of dementia, which is characterized by a decline in thinking and independence in personal daily activities.
Zeinab Breijyeh, R. Karaman
semanticscholar   +1 more source

Toward a multimodal multitask model for neurodegenerative diseases diagnosis and progression prediction [PDF]

open access: yes, 2021
Recent studies on modelling the progression of Alzheimer's disease use a single modality for their predictions while ignoring the time dimension. However, the nature of patient data is heterogeneous and time dependent which requires models that value these factors in order to achieve a reliable diagnosis, as well as making it possible to track and ...
arxiv   +1 more source

Hippocampus segmentation in magnetic resonance images of Alzheimer's patients using Deep machine learning [PDF]

open access: yes, 2021
Background: Alzheimers disease is a progressive neurodegenerative disorder and the main cause of dementia in aging. Hippocampus is prone to changes in the early stages of Alzheimers disease. Detection and observation of the hippocampus changes using magnetic resonance imaging (MRI) before the onset of Alzheimers disease leads to the faster preventive ...
arxiv   +1 more source

Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

open access: yesNature Communications, 2021
Alzheimer’s disease has been associated with increased structural brain aging. Here the authors describe a model that predicts brain aging from resting state functional connectivity data, and demonstrate this is accelerated in individuals with pre ...
Julie Gonneaud   +20 more
doaj   +1 more source

Introducing Vision Transformer for Alzheimer's Disease classification task with 3D input [PDF]

open access: yesarXiv, 2022
Many high-performance classification models utilize complex CNN-based architectures for Alzheimer's Disease classification. We aim to investigate two relevant questions regarding classification of Alzheimer's Disease using MRI: "Do Vision Transformer-based models perform better than CNN-based models?" and "Is it possible to use a shallow 3D CNN-based ...
arxiv  

A Clinicopathological Report of a 93-Year-Old Former Street Boxer With Coexistence of Chronic Traumatic Encephalopathy, Alzheimer's Disease, Dementia With Lewy Bodies, and Hippocampal Sclerosis With TDP-43 Pathology

open access: yesFrontiers in Neurology, 2020
Chronic traumatic encephalopathy (CTE) was recently recognized as a new tauopathy in which multifocal perivascular phosphorylated tau aggregates accumulate in neurons, astrocytes, and neurites at the depths of the cortical sulci.
Chunhui Yang   +8 more
doaj   +1 more source

2024 Alzheimer's disease facts and figures

open access: yesAlzheimer's & Dementia
This article describes the public health impact of Alzheimer's disease (AD), including prevalence and incidence, mortality and morbidity, use and costs of care and the ramifications of AD for family caregivers, the dementia workforce and society.

semanticscholar   +1 more source

The Amyloid-β Pathway in Alzheimer’s Disease

open access: yesMolecular Psychiatry, 2021
Breakthroughs in molecular medicine have positioned the amyloid-β (Aβ) pathway at the center of Alzheimer’s disease (AD) pathophysiology. While the detailed molecular mechanisms of the pathway and the spatial-temporal dynamics leading to synaptic failure,
H. Hampel   +14 more
semanticscholar   +1 more source

Using the A/T/N Framework to Examine Driving in Preclinical Alzheimer’s Disease

open access: yesGeriatrics, 2018
The A/T/N classification system is the foundation of the 2018 NIA-AA Research Framework and is intended to guide the Alzheimer disease (AD) research agenda for the next 5–10 years.
Catherine M. Roe   +9 more
doaj   +1 more source

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