Results 31 to 40 of about 9,294,018 (384)
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 2022 There are conventional screening instruments for the detection of cognitive impairment, but they have a reduced ecological validity and the information they present could be biased.
G. Palacios-Navarro +3 more
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Cold Spring Harbor Perspectives in Biology, 2011 Over the last three decades, advances in biochemical pathology and human genetics have illuminated one of the most enigmatic subjects in biomedicine--neurodegeneration.
D. Selkoe
semanticscholar +1 more source
Alzheimer's & Dementia, 2021 The estimate of people with clinical Alzheimer's disease (AD) and mild cognitive impairment provides an understanding of the disease burden.
K. Rajan +5 more
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Donanemab in Early Alzheimer's Disease.
New England Journal of Medicine, 2021 BACKGROUND A hallmark of Alzheimer's disease is the accumulation of amyloid-β (Aβ) peptide. Donanemab, an antibody that targets a modified form of deposited Aβ, is being investigated for the treatment of early Alzheimer's disease.
M. Mintun +12 more
semanticscholar +1 more source
2020 Alzheimer's disease facts and figures
Alzheimer's & Dementia, 2020 This article describes the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality and morbidity, use and costs of care, and the overall impact on caregivers and society.
semanticscholar +1 more source
Deciphering the factors that influence participation in studies requiring serial lumbar punctures
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020 Introduction Cerebrospinal fluid biomarkers increasingly inform the causes of dementia and may provide objective markers of disease progression. There is a need to decipher participant and procedural factors that promote participation in studies ...
Gregory S. Day +3 more
doaj +1 more source
The Road to Recovery: A Pilot Study of Driving Behaviors Following Antibody-Mediated Encephalitis
Frontiers in Neurology, 2020 Introduction: Safe driving requires integration of higher-order cognitive and motor functions, which are commonly compromised in patients with antibody-mediated encephalitis (AME) associated with N-methyl-D-aspartate receptors or leucine-rich glioma ...
Gregory S. Day +7 more
doaj +1 more source
Investigating Conversion from Mild Cognitive Impairment to Alzheimer's Disease using Latent Space Manipulation [PDF]
arXiv, 2021 Alzheimer's disease is the most common cause of dementia that affects millions of lives worldwide. Investigating the underlying causes and risk factors of Alzheimer's disease is essential to prevent its progression. Mild Cognitive Impairment (MCI) is considered an intermediate stage before Alzheimer's disease.
arxiv
Comprehensive Review on Alzheimer’s Disease: Causes and Treatment
Molecules, 2020 Alzheimer’s disease (AD) is a disorder that causes degeneration of the cells in the brain and it is the main cause of dementia, which is characterized by a decline in thinking and independence in personal daily activities.
Zeinab Breijyeh, R. Karaman
semanticscholar +1 more source
Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease
The journal of prevention of Alzheimer's disease, 2022 Alzheimer’s disease is a progressive, irreversible, and fatal disease for which accumulation of amyloid beta is thought to play a key role in pathogenesis.
Samantha Budd Haeberlein +23 more
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