Results 31 to 40 of about 317,693 (354)

Psychosis in Alzheimer’s Disease [PDF]

Current Neurology and Neuroscience Reports, 2020
AbstractPurpose of ReviewTo review the incidence, treatment and genetics of psychosis in people with mild cognitive impairment (MCI) and Alzheimer’s disease (AD).Recent FindingsPsychosis in Alzheimer’s disease (AD) has an incidence of ~ 10% per year. There is limited evidence regarding psychological interventions. Pharmacological management has focused
Robert A. Sweet, Clive Ballard, Roger Mills, Hilde Williams, Dag Aarsland, Dag Aarsland, Helen C. Kales, Byron Creese, Constantine G. Lyketsos   +8 more
openaire   +5 more sources

Deciphering the factors that influence participation in studies requiring serial lumbar punctures

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
Introduction Cerebrospinal fluid biomarkers increasingly inform the causes of dementia and may provide objective markers of disease progression. There is a need to decipher participant and procedural factors that promote participation in studies ...
Gregory S. Day, Tracy Rappai, Sushila Sathyan, John C. Morris   +3 more
doaj   +1 more source

The Road to Recovery: A Pilot Study of Driving Behaviors Following Antibody-Mediated Encephalitis

Frontiers in Neurology, 2020
Introduction: Safe driving requires integration of higher-order cognitive and motor functions, which are commonly compromised in patients with antibody-mediated encephalitis (AME) associated with N-methyl-D-aspartate receptors or leucine-rich glioma ...
Gregory S. Day, Gregory S. Day, Ganesh M. Babulal, Ganesh M. Babulal, Ganesh Rajasekar, Sarah Stout, Catherine M. Roe, Catherine M. Roe   +7 more
doaj   +1 more source

Alzheimer and vascular brain disease: Senile dementia. [PDF]

, 2015
Alois Alzheimer is best known for his description of a novel disease, subsequently named after him. However, his wide range of interests also included vascular brain diseases.
Engelhardt, Eliasz, Grinberg, Lea T
core   +2 more sources

Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer\u27s disease [PDF]

, 2019
Interest in understanding the roles of white matter (WM) inflammation and damage in the pathophysiology of Alzheimer disease (AD) has been growing significantly in recent years.
Ances, Beau M, Benzinger, Tammie L.S., Blazey, Tyler, Cairns, Nigel J, Chen, Charlie, Cruchaga, Carlos, Fagan, Anne M, Gordon, Brian A, Liu, Jingxia, Morris, John C, Shimony, Joshua S, Su, Yi, Sutphen, Courtney L, Wang, Qing, Wang, Yong   +14 more
core   +2 more sources

Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease

Nature Communications, 2021
Alzheimer’s disease has been associated with increased structural brain aging. Here the authors describe a model that predicts brain aging from resting state functional connectivity data, and demonstrate this is accelerated in individuals with pre ...
Julie Gonneaud, Alex T. Baria, Alexa Pichet Binette, Brian A. Gordon, Jasmeer P. Chhatwal, Carlos Cruchaga, Mathias Jucker, Johannes Levin, Stephen Salloway, Martin Farlow, Serge Gauthier, Tammie L. S. Benzinger, John C. Morris, Randall J. Bateman, John C. S. Breitner, Judes Poirier, Etienne Vachon-Presseau, Sylvia Villeneuve, Alzheimer’s Disease Neuroimaging Initiative (ADNI), Dominantly Inherited Alzheimer Network (DIAN) Study Group, Pre-symptomatic Evaluation of Experimental or Novel Treatments for Alzheimer’s Disease (PREVENT-AD) Research Group   +20 more
doaj   +1 more source

PAK in Alzheimer disease, Huntington disease and X-linked mental retardation. [PDF]

, 2012
Developmental cognitive deficits including X-linked mental retardation (XLMR) can be caused by mutations in P21-activated kinase 3 (PAK3) that disrupt actin dynamics in dendritic spines.
Cole, Greg M, Frautschy, Sally A, Ma, Qiu-Lan, Yang, Fusheng   +3 more
core   +1 more source

A Clinicopathological Report of a 93-Year-Old Former Street Boxer With Coexistence of Chronic Traumatic Encephalopathy, Alzheimer's Disease, Dementia With Lewy Bodies, and Hippocampal Sclerosis With TDP-43 Pathology

Frontiers in Neurology, 2020
Chronic traumatic encephalopathy (CTE) was recently recognized as a new tauopathy in which multifocal perivascular phosphorylated tau aggregates accumulate in neurons, astrocytes, and neurites at the depths of the cortical sulci.
Chunhui Yang, Sukriti Nag, Sukriti Nag, Guoqiang Xing, Neelum T. Aggarwal, Neelum T. Aggarwal, Julie A. Schneider, Julie A. Schneider, Julie A. Schneider   +8 more
doaj   +1 more source

Alzheimer and vascular brain diseases: Focal and diffuse subforms. [PDF]

, 2015
Alois Alzheimer is best known for his description of the pre-senile neurodegenerative disease named after him. However, his previous interest in vascular brain diseases, underlying cognitive and behavioral changes, was very strong. Besides describing the
Engelhardt, Eliasz, Grinberg, Lea T
core   +2 more sources

Using the A/T/N Framework to Examine Driving in Preclinical Alzheimer’s Disease

Geriatrics, 2018
The A/T/N classification system is the foundation of the 2018 NIA-AA Research Framework and is intended to guide the Alzheimer disease (AD) research agenda for the next 5–10 years.
Catherine M. Roe, Ganesh M. Babulal, Sarah H. Stout, David B. Carr, Monique M. Williams, Tammie L. S. Benzinger, Anne M. Fagan, David M. Holtzman, Beau M. Ances, John C. Morris   +9 more
doaj   +1 more source