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Archives of Microbiology, 1979
In order to understand the basis upon which amanitin-accumulating species of Amanita are able to develop in the presence of these specific inhibitors of RNA synthesis, the in vitro RNA synthesizing activities of nuclei isolated from amanitin-accumulating species.
James F Preston
exaly +3 more sources
In order to understand the basis upon which amanitin-accumulating species of Amanita are able to develop in the presence of these specific inhibitors of RNA synthesis, the in vitro RNA synthesizing activities of nuclei isolated from amanitin-accumulating species.
James F Preston
exaly +3 more sources
Comment on: amanitin intoxication
Clinical Toxicology, 2023Cellier, Morgane +6 more
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Synthesis of a Cytotoxic Amanitin for Biorthogonal Conjugation
ChemBioChem, 2015AbstractAlpha‐amanitin is an exceedingly toxic, naturally occurring, bicyclic octapeptide that inhibits RNA polymerase and results in cellular and organismal death. Here we report the straightforward synthesis of an amanitin analogue that exhibited near‐native toxicity.
Zhao L +7 more
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Comment on: Amanitin intoxication
Clinical Toxicology, 2022Brent A. Neuschwander-Tetri +1 more
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Antidotes to Experimental cc-Amanitin Poisoning
Nature New Biology, 1972THE two most important toxic cyclopeptides isolated from the mushroom Amanita phalloides (death cap) are phalloidin and α-amanitin1, 2. The latter is considered to be responsible for the fatal cases of poisoning. Up to now, protection has been demonstrated either with a non-toxic chemical analogue (antamanide) isolated from the toadstool itself and ...
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α-Amanitin: Inactivation by bovine lactoperoxidase
Experientia, 1979The principle amatoxin, alpha-amanitin, is found to be extremely sensitive toward lactoperoxidase catalyzed degradation, rather than iodination, of the indole nucleus. Extensive attenuation of inhibitor potency against eukaryotic DNA-dependent RNA polymerase II accompanies the treatment of alpha-amanitin with lactoperoxidase, iodide and hydrogen ...
P W, Morris, K M, Kelley, W G, Logas
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New Aspects of Amanitin and Phalloidin Poisoning
1996The green death cap Amanita phalloides produces two families of toxic peptides, the amatoxins and the phallotoxins. Amatoxins are by far the more dangerous toxins and account for all fatalities occurring in human mushroom poisoning.
H, Faulstich, T, Wieland
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Production of high purity beta amanitin
2012Amaç: Beta amanitin nadiren bilimsel araştırmalarda kullanılmakta ve kullanımı gün geçtikçeartmaktadır. Piyasada bu ürün %90 saflıkta ticari olarak satılmaktadır. Bu araştırmada yükseksaflıkta beta amanitin üretme yöntemi tanımlanmıştır.Yöntem: Saflaştırma işlemi Amanita phalloides mantarlarından ekstraksiyonla yapılmıştır.Öncelikle bu mantarlar ...
YAYKAŞLI, Kürşat Oğuz +5 more
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