Results 111 to 120 of about 600 (173)

Treatment of mushroom amanitin poisoning.

open access: yesThe Western journal of medicine, 1987
T J, Duffy, P, Vergeer
openaire   +1 more source
Some of the next articles are maybe not open access.

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Rationally Designed Amanitins Achieve Enhanced Cytotoxicity

Journal of Medicinal Chemistry, 2022
For 70 years, α-amanitin, the most cytotoxic peptide in its class, has been without a synthetic rival; through synthesis, we address the structure-activity relationships to inform the design of new amatoxins and disclose analogues that are more cytotoxic than the natural product when evaluated on CHO, HEK293, and HeLa cells, whereas on liver-derived ...
Mihajlo Todorovic   +2 more
exaly   +3 more sources

Unique amanitin resistance of RNA synthesis in isolated nuclei from Amanita species accumulating amanitins

Archives of Microbiology, 1979
In order to understand the basis upon which amanitin-accumulating species of Amanita are able to develop in the presence of these specific inhibitors of RNA synthesis, the in vitro RNA synthesizing activities of nuclei isolated from amanitin-accumulating species.
James F Preston
exaly   +3 more sources

Fifty years of amanitin

Experientia, 1991
Pharmacokinetic studies have provided new insights into human Amanita poisoning, but it appears to be impossible to treat this intoxication by immunotherapy. New synthetic analogs have revealed structure-activity relationships that were unknown so far.
T, Wieland, H, Faulstich
openaire   +2 more sources

Conformation and toxicity of amanitins

Experientia, 1973
Die Cottoneffekte der Amanitine konnten dem Indolteil bzw. den Amidgruppen des Molekuhls zugeordnet werden. Das untoxische Amanullin besitzt die gleiche Konformation wie die toxischen Peptide, das untoxische Aldoamanitin dagegen eine andere.
Faulstich, H.   +3 more
openaire   +3 more sources

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