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Toxicity of amantadine hydrochloride on cultured bovine cornea endothelial cells
Scientific Reports, 2021 Amantadine hydrochloride (HCl) is commonly prescribed for treating influenza A virus infection and Parkinson’s disease. Recently, several studies have indicated that the use of amantadine HCl is associated with corneal edema; however, the cytotoxic ...
Po-Yen Lee +14 more
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Pharmaceutics, 2021 Amantadine, a drug used for the blockage of NMDA receptors, is well-known to exhibit neuroprotective effects. Accordingly, assessment of amantadine transport at retinal barriers could result in the application of amantadine for retinal diseases such as ...
Yusuke Shinozaki +4 more
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Amantadine Toxicity in Apostichopus japonicus Revealed by Proteomics
Toxics, 2023 Amantadine exposure can alter biological processes in sea cucumbers, which are an economically important seafood in China. In this study, amantadine toxicity in Apostichopus japonicus was analyzed by oxidative stress and histopathological methods ...
Junqiang Zhao +12 more
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Myoclonus Secondary to Amantadine: Case Report and Literature Review
Clinics and Practice, 2023 The usual adverse events of amantadine are dizziness, dry mouth, and peripheral edema. Postmarketing experience has revealed abnormal movements such as tremors, involuntary muscle contractions, and gait abnormalities.
Jamir Pitton Rissardo +1 more
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Behavioral Recovery and Early Decision Making in Patients with Prolonged Disturbance in Consciousness after Traumatic Brain Injury [PDF]
, 2020 The extent of behavioral recovery that occurs in patients with traumatic disorders of consciousness (DoC) following discharge from the acute care setting has been under-studied and increases the risk of overly pessimistic outcome prediction.
Bagiella, Emilia +6 more
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Intravenous amantadine for freezing of gait resistant to dopaminergic therapy: a randomized, double-blind, placebo-controlled, cross-over clinical trial. [PDF]
PLoS ONE, 2012 Freezing of gait (FOG) is one of the most disabling symptoms in Parkinsonism. Open-label studies have suggested that intravenous (IV) amantadine is effective against FOG resistant to dopaminergic therapy in Parkinson's disease (PD).
Young Eun Kim +7 more
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Food and Agricultural Immunology, 2022 Amantadine is one of the most prescribed antiviral medications. Considering its abuse is life-threatening, monitoring amantadine residues is urgently needed.
Xiangxue Ning, Jing Qiu
doaj +1 more source
BMC Neurology, 2021 Background Amantadine hydrochloride is one of the most frequently prescribed drugs for patients with severe traumatic brain injury in restoring consciousness and accelerating the pace of functional recovery.
Jie Li +7 more
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Neurology and Therapy, 2019 Introduction In February 2018, OS320—an amantadine extended-release (ER) tablet formulation with once-daily morning administration—was approved for the treatment of Parkinson’s disease and drug-induced extrapyramidal reactions in adults.
Tina deVries +3 more
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De novo design of a homo-trimeric amantadine-binding protein. [PDF]
, 2019 The computational design of a symmetric protein homo-oligomer that binds a symmetry-matched small molecule larger than a metal ion has not yet been achieved.
Adams +36 more
core +2 more sources