Results 11 to 20 of about 28,899 (216)

Transcranial direct current stimulation combined with amantadine in repetitive mild traumatic brain injury in rats [PDF]

BMC Neuroscience, 2022
Background Balance and memory deficits are common in patients with repetitive mild traumatic brain injury (mTBI). Objective To investigate the combined effects of amantadine and transcranial direct current stimulation (tDCS) on balance and memory in ...
Soo Jeong Han, Gahee Park, Jee Hyun Suh
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Altered Mental Status Due to Amantadine Withdrawal: A Case Report [PDF]

Reports
Background and Clinical Significance: Withdrawal symptoms from an abrupt discontinuation or rapid dose reduction in amantadine has been documented as early as 1987. Symptoms can align with several diagnoses, including but not limited to infection, fever,
Nicole J. Asal, Elisa Piraino, Cristina Hamacher, Husam Abu Nejim   +3 more
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A Case Report of Severe Delirium after Amantadine Withdrawal [PDF]

Case Reports in Neurology, 2017
Amantadine is frequently used in addition to dopaminergic substances like dopamine agonists or L-Dopa in advanced Parkinson disease (PD). However, adverse effects like hallucinations limit its use.
Franz Marxreiter, Jürgen Winkler, Martin Uhl, Dominik Madžar   +3 more
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Amantadine variant – aryl conjugates that inhibit multiple M2 mutant – amantadine resistant influenza a viruses

European Journal of Medicinal Chemistry Reports, 2022
Influenza A viruses can cause a serious future threat due to frequent mutations. Amantadine and rimantadine drugs inhibit influenza A M2 wild-type (WT; bearing in the protein M2 proton channel serine at position-31) viruses by binding and blocking M2 WT ...
Christina Tzitzoglaki, Anja Hoffmann, Andreea L. Turcu, Patrick Schmerer, Chunlong Ma, George Laros, Christos Liolios, Brea José, Jun Wang, Santiago Vázquez, Michaela Schmidtke, Antonios Kolocouris   +11 more
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Amantadine Continuation After Hospital Discharge for Acute Stroke Requiring Inpatient Rehabilitation: A Long-term Follow-up Study [PDF]

Archives of Rehabilitation Research and Clinical Translation
Objectives: To describe the dosing strategy, safety, and effectiveness of amantadine in patients admitted to inpatient rehabilitation after stroke. Design: Retrospective, single-center, cohort study. Setting: Ninety-bed, inpatient rehabilitation hospital.
Haley R. Torr, PharmD, Sara Penrod, SLP-CCC, Jennifer Cote, OTR/L, Sara E. Hanken, PT, MPT, Stephanie C. Chan, MD, Richard R. Riker, MD, Angela Leclerc, MSPA, PA-C, Teresa L. May, DO, David B. Seder, MD, David J. Gagnon, PharmD   +9 more
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Successful Treatment With Intravenous Lipid Emulsion of Accidental Amantadine Overdose: A Case Report [PDF]

Veterinary Medicine and Science
A 2.5‐year‐old, 4.9 kg, Chinese Crested was accidentally administered a dose of 43.5 mg/kg of amantadine, resulting in the rapid onset of tremors, agitation, vertical nystagmus, and lack of pupillary light reflex in one eye.
Brett Hogberg, Kristen Marshall, Mark Vardanega   +2 more
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Improved survival in intensive care unit in severe COVID-19 associated with amantadine use - retrospective study

International Journal of Infectious Diseases, 2022
Objectives: Possible immunomodulatory effect of amantadine in patients treated in intensive care unit (ICU), mostly among patients with brain injuries or vascular diseases was observed in several studies.
Daniel Chober, Zenon Czajkowski, Bogusz Aksak-Wąs, Katarzyna Dalewska-Kucharczyk, Katarzyna Hołubczak, Sylwia Karasińska-Milchert, Mateusz Jaremko, Miłosz Skowron, Malwina Karasińska-Cieślak, Miłosz Parczewski   +9 more
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Antiglycoxidative properties of amantadine – a systematic review and comprehensive in vitro study

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
An important drug used in the treatment of Parkinson’s disease is amantadine. We are the first to perform a comprehensive study based on various glycation and oxidation factors, determining the impact of amantadine on protein glycoxidation.
Miłosz Nesterowicz, Małgorzata Żendzian-Piotrowska, Jerzy Robert Ładny, Anna Zalewska, Mateusz Maciejczyk   +4 more
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Amantadine Induced Corneal Edema in a Patient with Primary Progressive Freezing of Gait [PDF]

Journal of Movement Disorders, 2013
Amantadine is commonly used for Parkinsonism. However amantadine can induce adverse corneal reaction. Here we report a patient with primary progressive freezing of gait who had severe corneal edema associated with amantadine, which was reversible after ...
Young Eun Kim, Ji Young Yun, Hui-Jun Yang, Han-Joon Kim, Mee Kum Kim, Won Ryang Wee, Beom S. Jeon   +6 more
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Effect of Pre-exposure Use of Amantadine on COVID-19 Infection: A Hospital-Based Cohort Study in Patients With Parkinson's Disease or Multiple Sclerosis

Frontiers in Neurology, 2021
Background: Amantadine has been proposed to inhibit E-channel conductance in reconstituted lipid bilayers of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Walaa A. Kamel, Walaa A. Kamel, Mohmed I. Kamel, Almunther Alhasawi, Sameh Elmasry, Fajer AlHamdan, Jasem Y. Al-Hashel, Jasem Y. Al-Hashel   +7 more
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