Results 11 to 20 of about 26,228 (200)

Amantadine Toxicity in Apostichopus japonicus Revealed by Proteomics

Toxics, 2023
Amantadine exposure can alter biological processes in sea cucumbers, which are an economically important seafood in China. In this study, amantadine toxicity in Apostichopus japonicus was analyzed by oxidative stress and histopathological methods ...
Junqiang Zhao, Jianqiang Chen, Xiuhui Tian, Lisheng Jiang, Qingkui Cui, Yanqing Sun, Ningning Wu, Ge Liu, Yuzhu Ding, Jing Wang, Yongchun Liu, Dianfeng Han, Yingjiang Xu   +12 more
doaj   +1 more source

A semi-quantitative multi-range lateral flow immunoassay for amantadine residues in livestock and poultry products

Food and Agricultural Immunology, 2022
Amantadine is one of the most prescribed antiviral medications. Considering its abuse is life-threatening, monitoring amantadine residues is urgently needed.
Xiangxue Ning, Jing Qiu
doaj   +1 more source

Intravenous amantadine for freezing of gait resistant to dopaminergic therapy: a randomized, double-blind, placebo-controlled, cross-over clinical trial. [PDF]

PLoS ONE, 2012
Freezing of gait (FOG) is one of the most disabling symptoms in Parkinsonism. Open-label studies have suggested that intravenous (IV) amantadine is effective against FOG resistant to dopaminergic therapy in Parkinson's disease (PD).
Young Eun Kim, Ji Young Yun, Hui June Yang, Han-Joon Kim, Namyi Gu, Seo Hyun Yoon, Joo-Youn Cho, Beom S Jeon   +7 more
doaj   +1 more source

Myoclonus Secondary to Amantadine: Case Report and Literature Review

Clinics and Practice, 2023
The usual adverse events of amantadine are dizziness, dry mouth, and peripheral edema. Postmarketing experience has revealed abnormal movements such as tremors, involuntary muscle contractions, and gait abnormalities.
Jamir Pitton Rissardo, Ana Letícia Fornari Caprara   +1 more
doaj   +1 more source

Behavioral Recovery and Early Decision Making in Patients with Prolonged Disturbance in Consciousness after Traumatic Brain Injury [PDF]

, 2020
The extent of behavioral recovery that occurs in patients with traumatic disorders of consciousness (DoC) following discharge from the acute care setting has been under-studied and increases the risk of overly pessimistic outcome prediction.
Bagiella, Emilia, Christoforou, Andrea, Giacino, Joseph T., Hammond, Flora M., Long, David, Maurer-Karattup, Petra, Sherer, Mark   +6 more
core   +1 more source

Early amantadine treatment reduces the risk of death in patients with large hemisphere infarctions:a Chinese hospital-based study

BMC Neurology, 2021
Background Amantadine hydrochloride is one of the most frequently prescribed drugs for patients with severe traumatic brain injury in restoring consciousness and accelerating the pace of functional recovery.
Jie Li, Ping Zhang, Yingying Liu, Simiao Wu, Xingyang Yi, Shihong Zhang, Chun Wang, Ming Liu   +7 more
doaj   +1 more source

Bioavailability and Pharmacokinetics of Once-Daily Amantadine Extended-Release Tablets in Healthy Volunteers: Results from Three Randomized, Crossover, Open-Label, Phase 1 Studies

Neurology and Therapy, 2019
Introduction In February 2018, OS320—an amantadine extended-release (ER) tablet formulation with once-daily morning administration—was approved for the treatment of Parkinson’s disease and drug-induced extrapyramidal reactions in adults.
Tina deVries, Angela Dentiste, Lata Handiwala, David Jacobs   +3 more
doaj   +1 more source

De novo design of a homo-trimeric amantadine-binding protein. [PDF]

, 2019
The computational design of a symmetric protein homo-oligomer that binds a symmetry-matched small molecule larger than a metal ion has not yet been achieved.
Adams, Afonine, Arzt, Bale, Boyken, Campbell, Davis, Delaglio, DeRose, Dou, Dou, Emsley, Fegan, Ghirlanda, Guerrero, Hsia, Jancarik, Lee, Mallet, McCoy, Meilleur, Mills, Miyamoto, Nyanguile, Ollikainen, Otwinowski, Perez-Lloret, Polizzi, Spencer, Stankunas, Thomaston, Tinberg, Tzeng, Wang, Waudby, Winn, Zhang   +36 more
core   +2 more sources

Amantadine-induced corneal edema: A case and literature review

American Journal of Ophthalmology Case Reports, 2023
Purpose: To present a case of irreversible corneal edema after 10 years of amantadine use. A literature review was carried out to describe the clinical characteristics and outcomes of amantadine-induced corneal edema.
Antony Raharja, Wessam Mina, Zahra Ashena   +2 more
doaj   +1 more source

The sequence analysis of M2 gene for identification of amantadine resistance in avian influenza virus (H9N2 subtype), detected from broiler chickens with respiratory syndrome during 2016-2018, in Isfahan-Iran

Acta Scientiarum: Animal Sciences, 2022
vAmantadine and rimantadine are used for prevention and treatment of influenza A virus (IAV) infection. The rates of resistant IAVs have been increasing globally.
Majid Gholami-Ahangaran, Asal Basiratpour, Oveys Pourmahdi, Pedram Khorrami, Mehrdad Ostadpoor, Mohammad Javad Mirbagheri, Asiye Ahmadi-Dastgerdi   +6 more
doaj   +1 more source