Genetic correlations among diaphragmatic, femoral, inguinal, ventral, and umbilical hernias and identification of their candidate genes. [PDF]
Shi H +7 more
europepmc +1 more source
KRAS and MYC synergistic inhibition: a powerful strategy targeting KRAS-mutant cancers. [PDF]
Yan M +5 more
europepmc +1 more source
Arf6 and its ZEB1-EPB41L5 mesenchymal axis are required for both mesenchymal- and amoeboid-type invasion of cancer cells. [PDF]
Handa H +3 more
europepmc +1 more source
ASAP1 promotes extrahepatic cholangiocarcinoma progression by regulating the Wnt/β-catenin pathway in vitro and in vivo. [PDF]
He J +5 more
europepmc +1 more source
nicked β2-Glycoprotein Iの腫瘍転移抑制薬への応用
β2-Glycoprotein I (β2GPI)は、主に凝固線溶系における制御因子として解析されてきた。この分子はplasmin産生が亢進している状態下ではnicked formとして存在する。我々はこれまでにβ2GPIおよびnicked β2GPIが血管新生抑制物質であることを報告した。本研究ではVEGFR2の下流に存在し、腫瘍転移に重要な細胞内シグナル伝達経路GEP100-Arf6-AMAP1に対するβ2GPI、nicked β2GPIの制御能を評価し、腫瘍転移抑制分子としての機能を解析した ...
宮崎, 忠昭
core
Definition and Discovery of Tandem SH3-Binding Motifs Interacting with Members of the p47<sup>phox</sup>-Related Protein Family. [PDF]
Kalman ZE, Lazar T, Dobson L, Pancsa R.
europepmc +1 more source
Epithelial to mesenchymal transition thorough GEP100-Arf6-AMAP1 pathway in urothelial cancer [PDF]
オオヤ, モトツグ +14 more
core
The regulatory roles of RNA-binding proteins in the tumour immune microenvironment of gastrointestinal malignancies. [PDF]
Li D +5 more
europepmc +1 more source
Identification of Specific LncRNA Markers in Severe Tuberculosis for Early Diagnosis. [PDF]
Yao S, Ji X, Wang R, Pan L, Liu Q.
europepmc +1 more source
Tumor responsiveness to statins requires overexpression of the ARF6 pathway. [PDF]
Sabe H +3 more
europepmc +1 more source

