Results 81 to 90 of about 1,659 (163)

Phytochemical Characterization and Evaluation of the Anticholinesterase and Anti-Trypanosoma cruzi Potential of Andean Amaryllidaceae from Bolivia: (Pyrolirion boliviense and Stenomesson miniatum)

Life
The Amaryllidaceae family is a rich source of structurally diverse alkaloids with recognized neuroactive and antiparasitic properties. This study provides the first phytochemical and biological characterization of Pyrolirion boliviense and wild ...
María Lenny Rodríguez-Escobar, Vineet Singh Raj, Nieves Martínez-Peinado, Alfredo F. Fuentes, Carla Maldonado, Juan Carlos Gabaldón-Figueira, Julio Alonso-Padilla, Jaume Bastida, Luciana R. Tallini, Laura Torras-Claveria   +9 more
doaj   +1 more source

Phenolic Acids and Amaryllidaceae Alkaloids Profiles in Leucojum aestivum L. In Vitro Plants Grown under Different Light Conditions. [PDF]

Molecules, 2023
Morańska E, Simlat M, Warchoł M, Skrzypek E, Waligórski P, Laurain-Mattar D, Spina R, Ptak A.   +7 more
europepmc   +1 more source

Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells. [PDF]

Biomolecules, 2022
Mathieu V, Laguera B, Masi M, Dulanto SA, Bingham TW, Hernandez LW, Sarlah D, Evidente A, Lafontaine DLJ, Kornienko A, Lane MA.   +10 more
europepmc   +1 more source

Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme

Nature Communications
A major challenge to achieving industry-scale biomanufacturing of therapeutic alkaloids is the slow process of biocatalyst engineering. Amaryllidaceae alkaloids, such as the Alzheimer’s medication galantamine, are complex plant secondary metabolites with
Simon d’Oelsnitz, Daniel J. Diaz, Wantae Kim, Daniel J. Acosta, Tyler L. Dangerfield, Mason W. Schechter, Matthew B. Minus, James R. Howard, Hannah Do, James M. Loy, Hal S. Alper, Y. Jessie Zhang, Andrew D. Ellington   +12 more
doaj   +1 more source

Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents. [PDF]

Molecules, 2021
Maafi N, Mamun AA, Janďourek O, Maříková J, Breiterová K, Diepoltová A, Konečná K, Hošťálková A, Hulcová D, Kuneš J, Kohelová E, Koutová D, Šafratová M, Nováková L, Cahlíková L.   +14 more
europepmc   +1 more source

Neuroprotective Activities of Crossyne flava Bulbs and Amaryllidaceae Alkaloids: Implications for Parkinson's Disease. [PDF]

Molecules, 2021
Omoruyi SI, Ibrakaw AS, Ekpo OE, Boatwright JS, Cupido CN, Hussein AA.   +5 more
europepmc   +1 more source

Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids. [PDF]

Molecules, 2021
Maříková J, Mamun AA, Shammari LA, Korábečný J, Kučera T, Hulcová D, Kuneš J, Malaník M, Vašková M, Kohelová E, Nováková L, Cahlíková L, Pour M.   +12 more
europepmc   +1 more source

Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies. [PDF]

Int J Mol Sci, 2021
Mamun AA, Pidaný F, Hulcová D, Maříková J, Kučera T, Schmidt M, Catapano MC, Hrabinová M, Jun D, Múčková L, Kuneš J, Janoušek J, Andrýs R, Nováková L, Peřinová R, Maafi N, Soukup O, Korábečný J, Cahlíková L.   +18 more
europepmc   +1 more source

Amaryllidaceae alkaloids with anti-Trypanosoma cruzi activity. [PDF]

Parasit Vectors, 2020
Martinez-Peinado N, Cortes-Serra N, Torras-Claveria L, Pinazo MJ, Gascon J, Bastida J, Alonso-Padilla J.   +6 more
europepmc   +1 more source

Medicinal compounds and biotechnology of Amaryllidaceae alkaloids in <i>Lycoris radiata</i>. [PDF]

Front Plant Sci
Chen JX, Zheng J, Cai YM, Xu JX, Sun Y, Yang Z, Yang F, Chen MX, Chen Y, Li QZ.   +9 more
europepmc   +1 more source