Results 51 to 60 of about 443 (153)
Chemistry – A European Journal, Volume 30, Issue 19, April 2, 2024.Optionality for Indole‐based Peptide Stapling: hydroxypyrroloindoline, used regularly in reaction with cysteine to form a tryptathionine (Ttn) staple is found to react competitively with an indole to form a 2’2’‐bis‐indole tether (BITe). Judicious choice of protecting groups provides for chemoselectivity for optionality in terms of which staple is ...
Mihajlo Todorovic +9 more
wiley +1 more source
alpha-Amanitin induced apoptosis in primary cultured dog hepatocytes.
Folia Histochemica et Cytobiologica, 2010 Amatoxin poisoning is caused by mushroom species belonging to the genera Amanita, Galerina and Lepiota with the majority of lethal mushroom exposures attributable to Amanita phalloides.
Adam Szelag +8 more
doaj +1 more source
Bicyclic peptides: Paving the road for therapeutics of the future
Peptide Science, Volume 116, Issue 2, March 2024.Abstract Bicyclic peptides have emerged as one of the driving forces within the constrained peptide family. Due to their unique pharmaceutical attributes, peptide bicycles have garnered a reputation as promising therapeutics of the future. Combining advantages of small molecule therapeutics and biologics, the target binding qualities of this highly ...
Sven Ullrich, Christoph Nitsche
wiley +1 more source
The Turkish Journal of Gastroenterology, 2019 INTRODUCTION: Mushroom poisoning is observed in our country because of the consumption of wild mushrooms as unconscious food and the fact that poisonous mushroom species cannot be separated from non-toxic species.
Mustafa Zanyar Akkuzu +6 more
doaj +1 more source
ChemBioChem, Volume 25, Issue 3, February 1, 2024.The biosynthetic pathway for the peptide natural product omphalotin A of the agaricomycete Omphalotus olearius can be exploited for the production of non‐natural, multiply backbone N‐methylated peptide macrocycles in the yeast Pichia pastoris (Komagataella phaffii).
Emmanuel Matabaro +5 more
wiley +1 more source
Clinical characteristics and outcome of toxicity from Amanita mushroom poisoning
International Journal of General Medicine, 2017 Satariya Trakulsrichai,1,2 Charuwan Sriapha,2 Achara Tongpoo,2 Umaporn Udomsubpayakul,3 Sunun Wongvisavakorn,2 Sahaphume Srisuma,2,4 Winai Wananukul2,4 1Department of Emergency Medicine, 2Ramthibodi Poison Center, 3Section for Clinical Epidemiology and ...
Trakulsrichai S +6 more
doaj
Examining the associations between a generalist feeder and a highly toxic host
Ecology and Evolution, Volume 14, Issue 2, February 2024.We used a variety of behavioral assays to assess the association between a generalist feeder and a highly toxic host fungus. Our results suggest that access to a resource with lower competition may help to maintain this association. Abstract Understanding the often antagonistic plant–herbivore interactions and how host defenses can influence herbivore ...
Grace Kropelin, Clare H. Scott Chialvo
wiley +1 more source
HEMOPERFUSION IN AMANITA PHALLOİDES POISONING: REPORT OF TWO CASES
Turkish Journal of Nephrology, 2019 Amanita phalloides mushrooms are extremely toxic. Alpha-amanitin is an amatoxin known to produce deleterious effects on the liver and the kidneys, when circulating in the blood.
Osman DÖNMEZ +2 more
doaj
Amatoxins in edible mushrooms [PDF]
FEBS Letters, 1976 Faulstich, H., Cochet-Meilhac, M.
openaire +3 more sources
Over the past two years, I have devoted sustained research effort to the therapeutic potential of amatoxins as payloads in targeted cancer therapies. As the author of this work, amanitologist, Danny LeVan-Cicchetti, I have followed closely the notable advances that have taken place in this field between 2024 and 2026.
openaire +3 more sources