Results 41 to 50 of about 443 (153)

Application of single-pass albumin dialysis in the acute phase of amanitin syndrome caused by mushroom poisoning [PDF]

Vojnosanitetski Pregled
Introduction. The frequency of mushroom poisoning is increasing both in the world and in our country. The most poisonous type of mushroom in our region is Amanita phalloides, which causes amanitin syndrome in poisoned patients, and it is considered ...
Jovanović Dragana, Pilčević Dejan, Isailović Jelena, Vukčević Perković Nataša, Vuković Rade   +4 more
doaj   +1 more source

A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection

Food Frontiers, Volume 6, Issue 4, Page 1658-1700, July 2025.
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah, John‐Lewis Zinia Zaukuu   +1 more
wiley   +1 more source

Development of Simultaneous Analytical Method of Three Polypeptide Toxins α‐Amanitin, β‐Amanitin and Phalloidin in Poisonous Mushrooms and Human Serum Using UHPLC–MS/MS

Journal of Mass Spectrometry, Volume 60, Issue 6, June 2025.
ABSTRACT Accidental ingestion of toxic mushrooms remains a global public health concern because of the presence of highly potent peptide toxins such as α‐amanitin, β‐amanitin, and phalloidin. These compounds exhibit strong hepatotoxicity and can lead to acute liver failure and death.
Hang‐Ji Ok, Eun‐Young Park, Yongho Shin, Jeong‐Han Kim, Min‐Ho Song, Ji‐Ho Lee   +5 more
wiley   +1 more source

Early initiation of MARS® dialysis in Amanita phalloides-induced acute liver injury prevents liver transplantation

Annals of Hepatology, 2016
Amanita phalloides is the most relevant mushroom intoxication leading to acute liver failure. The two principal groups of toxins, the amatoxins and the phallotoxins, are small oligopeptides highly resistant to chemical and physical influences.
Mike Hendrik Pillukat, Tina Schomacher, Peter Baier, Gert Gabriëls, Hermann Pavenstädt, Hartmut H.J. Schmidt   +5 more
doaj   +1 more source

Mechanisms and aetiology‐dependent treatment of acute liver failure

Liver International, Volume 45, Issue 3, March 2025.
Abstract This review compiles the mechanisms of acute liver failure (ALF) as well as the current and potential therapeutic approaches, including aetiology‐specific treatment, and the issues encountered with such approaches. On a cellular level, ALF is characterized by massive hepatocyte death due to different types of cellular demise.
Peter Lemmer, Jan‐Peter Sowa, Yesim Bulut, Pavel Strnad, Ali Canbay   +4 more
wiley   +1 more source

Conceptual DFT as a Novel Chemoinformatics Tool for Studying the Chemical Reactivity Properties of the Amatoxin Family of Fungal Peptides

Open Chemistry, 2019
The chemical structures and molecular reactivities of the Amatoxin group of fungi-derived peptides have been determined by means of the consideration of a model chemistry that has been previously validated as well-behaved for our purposes. The reactivity
Flores-Holguín Norma, Frau Juan, Glossman-Mitnik Daniel   +2 more
doaj   +1 more source

Food Safety in Developing Countries: Common Foodborne and Waterborne Illnesses, Regulations, Organizational Structure, and Challenges of Food Safety in the Context of Nepal

Food Frontiers, Volume 6, Issue 1, Page 86-123, January 2025.
Food safety presents a global challenge, contributing to 600 million cases of foodborne diseases and 420,000 fatalities annually worldwide. A multisectoral One Health approach involving collaboration among government agencies, food industry stakeholders, consumers, and civil society organizations is imperative to enhance food safety in developing ...
Deepak Subedi, Madhav Paudel, Sandesh Poudel, Niranjan Koirala   +3 more
wiley   +1 more source

Morchella esculenta (L.) Pers. Wild of the Province of Taza, Morocco: Toxicity Assessment in In Vitro and In Vivo Models, Antioxidant Activities and Correlation With the Chemical Composition of Aqueous and Organic Extracts

Biochemistry Research International, Volume 2025, Issue 1, 2025.
Mushrooms are a source of nutrients and bioactive substances. This work, carried out for the first time, aims to evaluate in vitro and in vivo toxicity and antioxidant potential of the wild edible mushroom from the province of Taza, Morocco: Morchella esculenta (L.) Pers., the extraction is carried out using two methods: aqueous and organic.
Asmae Mahtal, Fatima Lamchouri, Nacima Lachkar, Hafida Bouhazama, Hamid Toufik, Harleen Khatra   +5 more
wiley   +1 more source

VISTA‐targeted antibody‐drug conjugates exhibit potent antitumor effects on malignant pleural mesothelioma

MedComm – Oncology, Volume 3, Issue 2, June 2024.
In this study, moderate to high V‐domain immunoglobulin T‐cell activation suppressor (VISTA) expression levels were observed in most malignant pleural mesothelioma (MPM) clinical tumor samples. We generated two novel VISTA‐targeted antibody‐drug conjugates by conjugating anti‐VISTA mAbs with the potent cytotoxic drug monomethyl auristatin E, which ...
Jingyue Kang, Zongliang Zhang, Ruyuan Zhang, Meijun Zheng, Caiying Jiang, Hui Yang, Aiping Tong, Yan Zhang   +7 more
wiley   +1 more source

Silymarin: Unveiling its pharmacological spectrum and therapeutic potential in liver diseases—A comprehensive narrative review

Food Science &Nutrition, Volume 12, Issue 5, Page 3097-3111, May 2024.
A thorough examination of the substantiating evidence supporting its use as an adjunctive therapy for individuals grappling with liver‐related conditions. Abstract Liver diseases, encompassing conditions such as cirrhosis, present a substantial global health challenge with diverse etiologies, including viral infections, alcohol consumption, and non ...
Hafiza Madiha Jaffar, Fahad Al‐Asmari, Faima Atta Khan, Muhammad Abdul Rahim, Eliasse Zongo   +4 more
wiley   +1 more source