Results 41 to 50 of about 465 (157)

Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species

PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana, Francis Martin, Rasmus Kjøller, Toby Spribille, Garima Singh   +4 more
wiley   +1 more source

Conceptual DFT as a Novel Chemoinformatics Tool for Studying the Chemical Reactivity Properties of the Amatoxin Family of Fungal Peptides

Open Chemistry, 2019
The chemical structures and molecular reactivities of the Amatoxin group of fungi-derived peptides have been determined by means of the consideration of a model chemistry that has been previously validated as well-behaved for our purposes. The reactivity
Flores-Holguín Norma, Frau Juan, Glossman-Mitnik Daniel   +2 more
doaj   +1 more source

A Critical Overview of Common Foodborne Toxicants and Methods for Their Reliable Detection

Food Frontiers, Volume 6, Issue 4, Page 1658-1700, July 2025.
ABSTRACT Food is an essential commodity for human health. However, toxicants such as mycotoxins, heavy metals, acrylamide, and pesticides can be present in food either naturally or through processing, packaging, or some anthropogenic activities. A thorough review of carefully selected studies revealed that climate change and pandemics have led to an ...
Betty Bowe Acquah, John‐Lewis Zinia Zaukuu   +1 more
wiley   +1 more source

Development of Simultaneous Analytical Method of Three Polypeptide Toxins α‐Amanitin, β‐Amanitin and Phalloidin in Poisonous Mushrooms and Human Serum Using UHPLC–MS/MS

Journal of Mass Spectrometry, Volume 60, Issue 6, June 2025.
ABSTRACT Accidental ingestion of toxic mushrooms remains a global public health concern because of the presence of highly potent peptide toxins such as α‐amanitin, β‐amanitin, and phalloidin. These compounds exhibit strong hepatotoxicity and can lead to acute liver failure and death.
Hang‐Ji Ok, Eun‐Young Park, Yongho Shin, Jeong‐Han Kim, Min‐Ho Song, Ji‐Ho Lee   +5 more
wiley   +1 more source

Mechanisms and aetiology‐dependent treatment of acute liver failure

Liver International, Volume 45, Issue 3, March 2025.
Abstract This review compiles the mechanisms of acute liver failure (ALF) as well as the current and potential therapeutic approaches, including aetiology‐specific treatment, and the issues encountered with such approaches. On a cellular level, ALF is characterized by massive hepatocyte death due to different types of cellular demise.
Peter Lemmer, Jan‐Peter Sowa, Yesim Bulut, Pavel Strnad, Ali Canbay   +4 more
wiley   +1 more source

Food Safety in Developing Countries: Common Foodborne and Waterborne Illnesses, Regulations, Organizational Structure, and Challenges of Food Safety in the Context of Nepal

Food Frontiers, Volume 6, Issue 1, Page 86-123, January 2025.
Food safety presents a global challenge, contributing to 600 million cases of foodborne diseases and 420,000 fatalities annually worldwide. A multisectoral One Health approach involving collaboration among government agencies, food industry stakeholders, consumers, and civil society organizations is imperative to enhance food safety in developing ...
Deepak Subedi, Madhav Paudel, Sandesh Poudel, Niranjan Koirala   +3 more
wiley   +1 more source

Morchella esculenta (L.) Pers. Wild of the Province of Taza, Morocco: Toxicity Assessment in In Vitro and In Vivo Models, Antioxidant Activities and Correlation With the Chemical Composition of Aqueous and Organic Extracts

Biochemistry Research International, Volume 2025, Issue 1, 2025.
Mushrooms are a source of nutrients and bioactive substances. This work, carried out for the first time, aims to evaluate in vitro and in vivo toxicity and antioxidant potential of the wild edible mushroom from the province of Taza, Morocco: Morchella esculenta (L.) Pers., the extraction is carried out using two methods: aqueous and organic.
Asmae Mahtal, Fatima Lamchouri, Nacima Lachkar, Hafida Bouhazama, Hamid Toufik, Harleen Khatra   +5 more
wiley   +1 more source

VISTA‐targeted antibody‐drug conjugates exhibit potent antitumor effects on malignant pleural mesothelioma

MedComm – Oncology, Volume 3, Issue 2, June 2024.
In this study, moderate to high V‐domain immunoglobulin T‐cell activation suppressor (VISTA) expression levels were observed in most malignant pleural mesothelioma (MPM) clinical tumor samples. We generated two novel VISTA‐targeted antibody‐drug conjugates by conjugating anti‐VISTA mAbs with the potent cytotoxic drug monomethyl auristatin E, which ...
Jingyue Kang, Zongliang Zhang, Ruyuan Zhang, Meijun Zheng, Caiying Jiang, Hui Yang, Aiping Tong, Yan Zhang   +7 more
wiley   +1 more source

alpha-Amanitin induced apoptosis in primary cultured dog hepatocytes.

Folia Histochemica et Cytobiologica, 2010
Amatoxin poisoning is caused by mushroom species belonging to the genera Amanita, Galerina and Lepiota with the majority of lethal mushroom exposures attributable to Amanita phalloides.
Adam Szelag, Marzena Podhorska-Okołów, Agnieszka Gomułkiewicz, Marcin Nowak, Ilona Izykowska, Aleksandra Piotrowska, Alina Ostrowska, Jan Magdalan, Piotr Dziegiel   +8 more
doaj   +1 more source

Silymarin: Unveiling its pharmacological spectrum and therapeutic potential in liver diseases—A comprehensive narrative review

Food Science &Nutrition, Volume 12, Issue 5, Page 3097-3111, May 2024.
A thorough examination of the substantiating evidence supporting its use as an adjunctive therapy for individuals grappling with liver‐related conditions. Abstract Liver diseases, encompassing conditions such as cirrhosis, present a substantial global health challenge with diverse etiologies, including viral infections, alcohol consumption, and non ...
Hafiza Madiha Jaffar, Fahad Al‐Asmari, Faima Atta Khan, Muhammad Abdul Rahim, Eliasse Zongo   +4 more
wiley   +1 more source