Results 21 to 30 of about 465 (157)

Amanita Section Phalloideae Species in the Mediterranean Basin: Destroying Angels Reviewed

Biology, 2022
In Europe, amatoxin-containing mushrooms are responsible for most of the deadly poisonings caused by macrofungi. The present work presents a multidisciplinary revision of the European species of Amanita sect.
Pablo Alvarado, Antonia Gasch-Illescas, Sylvie Morel, Magda Bou Dagher-Kharrat, Gabriel Moreno, José Luis Manjón, Xavier Carteret, Jean-Michel Bellanger, Sylvie Rapior, Matteo Gelardi, Pierre-Arthur Moreau   +10 more
doaj   +1 more source

Toxicokinetics of β-Amanitin in Mice and In Vitro Drug–Drug Interaction Potential

Pharmaceutics, 2022
The toxicokinetics of β-amanitin, a toxic bicyclic octapeptide present abundantly in Amanitaceae mushrooms, was evaluated in mice after intravenous (iv) and oral administration.
Young Yoon Bang, Im-Sook Song, Min Seo Lee, Chang Ho Lim, Yong-Yeon Cho, Joo Young Lee, Han Chang Kang, Hye Suk Lee   +7 more
doaj   +1 more source

Protective Effect and Mechanism of Rosiglitazone in α-amanitin-induced Hepatotoxicity Via Activation of PPAR-γ/Nrf2 Signaling Pathway. [PDF]

J Biochem Mol Toxicol
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Lai F, Liao Y, Wu J, Wang T, Zhang G, Zhang X, Xia C, Hu J, Lu Y.   +8 more
europepmc   +2 more sources

"Last supper with mushroom soup": a case report of amatoxin poisoning

McGill Journal of Medicine, 2020
N ...
Rabindra Nath Das, S Parajuli, J Jayakumar   +2 more
doaj   +1 more source

Investigation and analysis of a poisoning incident caused by Amanita fuliginea in Chenzhou

Zhongguo shipin weisheng zazhi, 2021
ObjectiveTo investigate an incident of mushroom poisoning in Chenzhou, Hunan province in June 2020, analyze the cause of the incident, and provide a basis for formulating prevention and control measures.MethodsEpidemiological investigation was carried ...
LIU Xun, ZHOU Liang, QIU Bin, CAO Yongping, LUO Rui, LIAO Bin, OU Shexiang   +6 more
doaj   +1 more source

The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes

IMA Fungus, 2018
The biosynthetic pathway for amanitins and related cyclic peptides in deadly Amanita (Amanitaceae) mushrooms represents the first known ribosomal cyclic peptide pathway in the Fungi.
Hong Luo, Qing Cai, Yunjiao Lüli, Xuan Li, Rohita Sinha, Heather E. Hallen-Adams, Zhu L. Yang   +6 more
doaj   +1 more source

Analysis of α- and β-amanitin in Human Plasma at Subnanogram per Milliliter Levels by Reversed Phase Ultra-High Performance Liquid Chromatography Coupled to Orbitrap Mass Spectrometry

Toxins, 2020
Amatoxins are known to be one of the main causes of serious to fatal mushroom intoxication. Thorough treatment, analytical confirmation, or exclusion of amatoxin intake is crucial in the case of any suspected mushroom poisoning.
Thomas P. Bambauer, Lea Wagmann, Armin A. Weber, Markus R. Meyer   +3 more
doaj   +1 more source

A Simple and High-Throughput Analysis of Amatoxins and Phallotoxins in Human Plasma, Serum and Urine Using UPLC-MS/MS Combined with PRiME HLB μElution Platform

Toxins, 2016
Amatoxins and phallotoxins are toxic cyclopeptides found in the genus Amanita and are among the predominant causes of fatal food poisoning in China.
Shuo Zhang, Yunfeng Zhao, Haijiao Li, Shuang Zhou, Dawei Chen, Yizhe Zhang, Qunmei Yao, Chengye Sun   +7 more
doaj   +1 more source

Analytical methods for amatoxins: A comprehensive review

Journal of Pharmaceutical and Biomedical Analysis, 2023
Amatoxins are toxic bicyclic octapeptides found in certain wild mushroom species, particularly Amanita phalloides. These mushrooms contain predominantly α- and β-amanitin, which can lead to severe health risks for humans and animals if ingested.
Isabel, Barbosa, Cátia, Domingues, Fernando, Ramos, Rui M, Barbosa   +3 more
openaire   +2 more sources

Research Progress on the Establishment of Animal Models of Amanita Toxin Poisoning

Journal of Forensic Science and Medicine
Amatoxin is the primary lethal component of highly toxic Amanita species, inducing severe liver failure or even multiple organ failure, with no specific clinical treatments available. Establishing amatoxin poisoning animal models is critical for studying
Haowei Wang, Xinyu Zhang, Teng Sun, Xiaodong Li, Shangwen Wang, Xiaofeng Zeng   +5 more
doaj   +1 more source