Results 11 to 20 of about 443 (153)

Amanitins: The Most Poisonous Molecules of the Fungal World [PDF]

Molecules, 2023
Among the toxic metabolites of the fungal world, those that, due to their strong biological effect, can seriously (even fatally) damage the life processes of humans (and certain groups of animals) stand out.
János Vetter
doaj   +2 more sources

A Rare Case of Amatoxin Poisoning in the State of Texas [PDF]

Case Reports in Gastroenterology, 2012
Ingestion of mushrooms from the genus Amanita can present detrimental consequences to the human body. The mushroom is frequently found in the coastal Pacific Northwest, Pennsylvania, New Jersey, and Ohio. Amanitin, one of the two distinct toxins isolated
Wei-Chung Chen, Mahwash Kassi, Umair Saeed, Catherine T. Frenette   +3 more
doaj   +3 more sources

Effects of interrupting the enterohepatic circulation in amatoxin intoxications

Clinical Toxicology
Interruption of the enterohepatic circulation is regarded as an effective way to treat patients with amatoxin poisoning. Nonetheless, its effectiveness has not yet been systematically evaluated. Therefore, we performed a systematic review to investigate the role of enterohepatic circulation on patient outcome and clinical laboratory values.
Jia Lin Tan, Janine Stam, Patrick F Van Rheenen   +2 more
exaly   +4 more sources

Amanitine poisoning - cases, management, therapy results

Journal of Education, Health and Sport, 2023
Mushroom poisoning continues to be a serious clinical problem. The most serious are intoxications with mushrooms containing cytotropic toxins with predominant injury of liver, kidneys and heart. The toxic properties of the phalloides are mainly due to α-
Magdalena Kubicka, Joanna Wilk, Paweł Dębiec, Krystian Cholewa, Magdalena Makarewicz, Adrianna Szymańska   +5 more
doaj   +1 more source

Toxicity Mechanisms and Potential Uses of Extracted Mushroom Toxins - Amatoxin, Antamanide, Muscurine [PDF]

E3S Web of Conferences, 2021
Mushroom, as a popular kind of wild edible fungi, has raised the attention of many scientists around the globe, due to the fact that increasing numbers of fatal mushroom poisoning cases worldwide have been reported each year.
Liang Xiaochen, Wang Tianxu
doaj   +1 more source

Hypoadrenocorticism in a Dog Following Recovery from Alpha-Amanitin Intoxication

Veterinary Sciences, 2023
A 10-year-old, female spayed Labrador Retriever was referred for acute hepatopathy and urinary retention. Blood work from the initial presentation (day 0) revealed a severe, mixed hepatopathy. Over the course of the patient’s hospitalization, the patient
Emily A. Cohen, Courtney M. Moeller, Jonathan D. Dear   +2 more
doaj   +1 more source

Equipped for success: genomes and metabolomes of the European Amanita muscaria are conserved in its novel South African range. [PDF]

New Phytol
Summary Plants and soils have been moved around the world for centuries, but invasive mushrooms receive scant attention. The Amanita muscaria species complex was introduced to South Africa in the context of forestry, but its origins, ecology and recent evolution are unstudied. We sequenced the genomes of 24 Northern and Southern Hemisphere A. muscaria,
Nickles GR, Stokes CK, Narh DL, Lynn KMT, Fuqua SR, Bryan C, Allen BM, Bivins CP, Woo Bok J, Brewer JS, Buthelezi ST, Clark JPRM, Coon KL, Corby LR, Coetzee MPA, Dewing C, Duong TA, Harris MA, Keller NP, Kopotsa K, Lane FA, Nichols HL, Nieuwoudt A, Nuñez MA, Medina Munoz ME, Park SC, Pham NQ, Ryan KT, Solís M, Vilgalys R, Wallace JM, Wang YW, Wingfield BD, Wingfield MJ, Worley TK, Zallek TA, Zamanian M, Hoeksema JD, Drott MT, Pringle A.   +39 more
europepmc   +2 more sources

Analytical methods for amatoxins: A comprehensive review

Journal of Pharmaceutical and Biomedical Analysis, 2023
Amatoxins are toxic bicyclic octapeptides found in certain wild mushroom species, particularly Amanita phalloides. These mushrooms contain predominantly α- and β-amanitin, which can lead to severe health risks for humans and animals if ingested.
Isabel, Barbosa, Cátia, Domingues, Fernando, Ramos, Rui M, Barbosa   +3 more
openaire   +2 more sources

Protective Effect and Mechanism of Rosiglitazone in α-amanitin-induced Hepatotoxicity Via Activation of PPAR-γ/Nrf2 Signaling Pathway. [PDF]

J Biochem Mol Toxicol
ABSTRACT α‐amanitin (α‐AMA), the primary lethal toxin of amanita, primarily targets the liver with a high toxicity and a low lethal dose. As the precise mechanism of intoxication is unclear, and specific antidotes are lacking, α‐AMA‐induced liver injury has a high mortality rate.
Lai F, Liao Y, Wu J, Wang T, Zhang G, Zhang X, Xia C, Hu J, Lu Y.   +8 more
europepmc   +2 more sources

A 3-Year Survey of Mushroom-Poisoned Patients: Clinical Features, Management and Outcomes [PDF]

Asia Pacific Journal of Medical Toxicology, 2018
Background:Besides their nutritional value, mushrooms have shown beneficial effects on human body organs; thus, people are interested in consumption of mushrooms regardless of their safety.
Samaneh Silakhori, Bita Dadpour, Mona Najaf Najafi   +2 more
doaj   +1 more source