Results 71 to 80 of about 5,969 (169)

Cardiovascular and hepatic toxicity of cocaine: potential beneficial effects of modulators of oxidative stress [PDF]

, 2015
Oxidative stress (OS) is thought to play an important role in the pharmacological and toxic effects of various drugs of abuse. Herein we review the literature on the mechanisms responsible for the cardiovascular and hepatic toxicity of cocaine with ...
Antonilli, Letizia, Badiani, Aldo, Grassi, Maria Caterina, Graziani, Manuela, Saso, Luciano, Togna, Anna Rita   +5 more
core   +4 more sources

Molecular Mechanisms of Chronic Pain and Therapeutic Interventions

MedComm, Volume 6, Issue 8, August 2025.
We offer a comprehensive overview of the distinctive molecular mechanisms underlying nociceptive, neuropathic, and nociplastic pain, including the immune responses, ion channels, monoaminergic imbalance, and neuroinflammation. Subsequently, we summarized the status quo of nociceptive, neuropathic, and nociplastic pain managementmanipulation.
Zhen Li, Xing Li, Jieqiong Liu, Rao Sun, Yingze Ye, Hongbing Xiang, Fang Luo, Shiyong Li, Ailin Luo   +8 more
wiley   +1 more source

Studi Kasus: Konfirmasi Kasus Flu Burung Di Kota Bengkulu Provinsi Bengkulu Tahun 2012 [PDF]

, 2016
Outbreak Command Post reported that there was a suspected case of Avian Influenza, a woman, 24 year old from the village of Dahri, sub-district of Ratu Samban, in the Province of Bengkulu.
Pratiwi, E. (Eka), Putranto, R. H. (Rudi)   +1 more
core   +2 more sources

The role of reactive enteric glia‐macrophage interactions in acute and chronic inflammation

Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
Abstract Enteric glia are a heterogeneous population of peripheral glia within the enteric nervous system and play pivotal roles in gut homeostasis, tissue integrity, coordination of motility, and intestinal immune responses. Under physiological conditions, they communicate with enteric neurons to control intestinal motility.
Schneider Reiner, Schneider Linda, Hamza Ebrahim, Leven Patrick, Wehner Sven   +4 more
wiley   +1 more source

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source

Biofilm The Formation in Respiratory Diseases. Influence of Ambroxol on Airway Biofilms (Literature Review)

Zdorovʹe Rebenka, 2016
This article reviews the literature on the development of biofilms on airway in respiratory diseases and the impact of ambroxol on them. Since biofilm infections respond poorly to standard antibiotic therapy, their treatment is a serious challenge in the
Yu.V. Marushko, T.V. Hyshchak
doaj   +1 more source

Simultaneous determination of amoxicillin and clavulanic acid in the human plasma by high performance liquid chromatography: Mass spectrometry (UPLC/MS) [PDF]

, 2010
Background/Aim. Quantitative analysis of amoxicillin and clavulanic acid in biological matrices requires sensitive and specific methods which allow determination of therapeutic concentration in μg/mL range.
Dragojević-Simić Viktorija, Jandrić Dušan, Jović-Stošić Jasmina, Kilibarda Vesna, Vučinić Slavica, Ćirić Biljana   +5 more
core   +1 more source

Rapid and long‐lasting efficacy of high‐dose ambroxol therapy for neuronopathic Gaucher disease: A case report and literature review

Molecular Genetics & Genomic Medicine
Gaucher disease (GD) is a lysosomal storage disorder caused by a deficiency in the GBA1‐encoded enzyme, β‐glucocerebrosidase. Enzyme replacement therapy is ineffective for neuronopathic Gaucher disease (nGD).
Kanako Higashi, Yuri Sonoda, Noriyuki Kaku, Fumihiko Fujii, Fumiya Yamashita, Sooyoung Lee, Vlad Tocan, Go Ebihara, Wakato Matsuoka, Kenichi Tetsuhara, Motoshi Sonoda, Pin Fee Chong, Yuichi Mushimoto, Kanako Kojima‐Ishii, Masataka Ishimura, Yuhki Koga, Atsuhisa Fukuta, Nana Akagi Tsuchihashi, Yoshikazu Kikuchi, Takahito Karashima, Takaaki Sawada, Taeko Hotta, Makoto Yoshimitsu, Hideyuki Terazono, Tatsuro Tajiri, Takashi Nakagawa, Yasunari Sakai, Kimitoshi Nakamura, Shouichi Ohga   +28 more
doaj   +1 more source

Evaluación de resultados del proyecto derecho al acceso a medicamentos esenciales, desde la perspectiva de pacientes crónicos de la tercera edad en la zona seis del municipio de ciudad Sandino, Managua, Nicaragua. 2008-2010 [PDF]

, 2017
Este estudio, presenta el análisis de los resultados del proyecto Derechos al acceso a medicamentos esenciales período 2008-2010, desde la perspectiva de los pacientes crónicos de la tercera edad, en uno de doce territorios de intervención: el municipio ...
Duriettz Marenco, Marlon Alonso
core  

Electrochemical Behavior of Ambroxol and Its Determination in Pharmaceutical Dosage Forms on MWCNT/Nafion Modified Glassy Carbon Electrodes

International Journal of Electrochemical Science, 2012
The electrochemical behavior of ambroxol was investigated on MWCNT/Nafion modified glassy carbon electrodes. In cyclic voltammetry, the compound showed an irreversible oxidation peak.
Yuanzhe Piao
doaj   +1 more source