Results 61 to 70 of about 3,769 (208)
Brain and Behavior, Volume 16, Issue 6, June 2026.In 33 Hakka young‐onset Parkinson's disease (YOPD) patients from western Fujian, whole exome sequencing (WES) plus spinocerebellar ataxia (SCA) panel testing and multiplex ligation‐dependent probe amplification (MLPA) defined the genetic spectrum. Pathological ATXN2 repeat expansion was detected in two cases.
Li‐Ying Pan +5 more
wiley +1 more source
Ambroxol effects in glucocerebrosidase and α‐synuclein transgenic mice
, 2016 International audienceGaucher disease is caused by mutations in the glucocerebrosidase 1 gene that result in deficiency of the lysosomal enzyme glucocerebrosidase.
Migdalska-Richards, Anna +7 more
core +1 more source
Архивъ внутренней медицины, 2013 Archiv vnutrenney meditsiny presents material on rational treatment of cough in modern conditions to physicians and communicating specialists. The article states medical practitioner’s points of view on ambroxol (Ambrobene) and clinical cases where this ...
В. И. Трофимов +3 more
doaj +1 more source
, 2023 <p>Os xaropes broncodilatadores desempenham um papel importante no tratamento das doenças respiratórias, ajudando no alívio dos sintomas como tosse, insuficiência respiratória, chiado no peito e congestão nasal.
Anne Caroline Nogueira de Oliveira1 Gustavo Braz Vale de Souza2 Vanessa Castro de Oliveira3 Rodrigo Queiroz de Lima4
core +1 more source
Plasma Glucosylsphingosine in GBA1 E365K, N409S, and L483P Heterozygous Mutation Carriers
Movement Disorders, Volume 41, Issue 5, Page 1304-1309, May 2026.Abstract Background GBA1 encodes the lysosomal enzyme glucocerebrosidase, with key substrates that include glucosylceramide and glucosylsphingosine. The E365K variant is the most common variant in GBA1 that is associated with Parkinson's disease (PD) but is not associated with Gaucher disease.
Julian Agin‐Liebes +7 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Foix‐Chavany‐Marie Syndrome (FCMS), also known as opercular syndrome, is a rare neurological disorder caused by an ischemic stroke that results in autonomic‐voluntary dissociation. In this case report, we describe a patient who presented with an acute right frontal and parietal cortical lesion, in addition to a remote infarction in the left ...
Lu Xia +7 more
wiley +1 more source
BMC Neurology, 2019 Background Currently there are no disease-modifying treatments for Parkinson’s disease dementia (PDD), a condition linked to aggregation of the protein α-synuclein in subcortical and cortical brain areas.
C. R. A. Silveira +17 more
doaj +1 more source
COVID‐19 Prophylactic Effect of Bromhexine Hydrochloride
Immunity, Inflammation and Disease, Volume 14, Issue 4, April 2026.ABSTRACT Introduction Despite extensive efforts to identify effective treatments for COVID‐19, preventive strategies remain essential. Bromhexine hydrochloride (BRH), an over‐the‐counter mucolytic with potential TMPRSS2 inhibition, may reduce viral entry and thus serve as a prophylactic agent.
Vanyo Mitev +4 more
wiley +1 more source
Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids
Movement Disorders, Volume 41, Issue 3, Page 581-595, March 2026.Abstract Neurodegenerative diseases are pathological states characterized by progressive alterations in brain homeostasis during aging. Synucleinopathies, including Parkinson's disease and dementia with Lewy bodies, are defined neuropathologically by the accumulation of inclusions known as Lewy bodies and Lewy neurites.
Manuel Flores‐León, Tiago F. Outeiro
wiley +1 more source
Comparison of Clinical Outcomes Between Acetylcysteine and Ambroxol in Post Acute Exacerbation of COPD Patients [PDF]
Literature studies show that the use of acetylcysteine or ambroxol can accelerate improvement of clinical outcomes of post acute exacerbation chronic obstructive pulmonary disease (AECOPD) patients.
Pramantara, Dewa Putu +2 more
core +1 more source