Results 61 to 70 of about 305 (130)

Rapid and long‐lasting efficacy of high‐dose ambroxol therapy for neuronopathic Gaucher disease: A case report and literature review

Molecular Genetics & Genomic Medicine
Gaucher disease (GD) is a lysosomal storage disorder caused by a deficiency in the GBA1‐encoded enzyme, β‐glucocerebrosidase. Enzyme replacement therapy is ineffective for neuronopathic Gaucher disease (nGD).
Kanako Higashi, Yuri Sonoda, Noriyuki Kaku, Fumihiko Fujii, Fumiya Yamashita, Sooyoung Lee, Vlad Tocan, Go Ebihara, Wakato Matsuoka, Kenichi Tetsuhara, Motoshi Sonoda, Pin Fee Chong, Yuichi Mushimoto, Kanako Kojima‐Ishii, Masataka Ishimura, Yuhki Koga, Atsuhisa Fukuta, Nana Akagi Tsuchihashi, Yoshikazu Kikuchi, Takahito Karashima, Takaaki Sawada, Taeko Hotta, Makoto Yoshimitsu, Hideyuki Terazono, Tatsuro Tajiri, Takashi Nakagawa, Yasunari Sakai, Kimitoshi Nakamura, Shouichi Ohga   +28 more
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Biofilm The Formation in Respiratory Diseases. Influence of Ambroxol on Airway Biofilms (Literature Review)

Zdorovʹe Rebenka, 2016
This article reviews the literature on the development of biofilms on airway in respiratory diseases and the impact of ambroxol on them. Since biofilm infections respond poorly to standard antibiotic therapy, their treatment is a serious challenge in the
Yu.V. Marushko, T.V. Hyshchak
doaj   +1 more source

Therapeutic Potential of Ambroxol in Osteoarthritis: A Drug Repurposing Study

Pharmaceuticals
Background/Objectives: Ambroxol is a mucolytic agent widely used in the treatment of respiratory diseases; however, evidence in the literature indicates anti-inflammatory, analgesic, and immunomodulatory properties, suggesting potential for therapeutic ...
Michelline Joana Tenório Albuquerque Madruga Mesquita, Anne Caroline Silva Nogueira da Cruz, Joana Tenório Albuquerque Madruga Mesquita Meireles Teixeira, Amanda Tissore Forwille Reis, Gustavo Medeiro Frota, Taciana Gabrielle Pinheiro de Moura Carvalho, Rafael Antônio Freire Carvalho, Jorge Antônio Meireles Teixeira, Marcelo Souza de Andrade, Rafael Cardoso Carvalho, Eduardo Martins de Sousa, Joicy Cortez de Sá Sousa, Sebastião Vieira de Morais, Eduardo Rodrigues Silva, Maria do Socorro de Sousa Cartágenes, João Batista Santos Garcia   +15 more
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Electrochemical Behavior of Ambroxol and Its Determination in Pharmaceutical Dosage Forms on MWCNT/Nafion Modified Glassy Carbon Electrodes

International Journal of Electrochemical Science, 2012
The electrochemical behavior of ambroxol was investigated on MWCNT/Nafion modified glassy carbon electrodes. In cyclic voltammetry, the compound showed an irreversible oxidation peak.
Yuanzhe Piao
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Characterization of differential patient profiles and therapeutic responses of pharmacy customers for four ambroxol formulations

BMC Pharmacology and Toxicology, 2018
Background Ambroxol relieves cough symptoms based on its secretagogue, anti-inflammatory, anti-oxidant, anti-bacterial, anti-viral, immunomodulatory and local anesthetic effects. The present study was designed to explore differential patient profiles and
Peter Kardos, Kai-Michael Beeh, Ulrike Sent, Tobias Mueck, Heidemarie Gräter, Martin C. Michel   +5 more
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Ambroxol as a pharmacological chaperone for mutant glucocerebrosidase

Blood Cells, Molecules, and Diseases, 2013
Gaucher disease (GD) is characterized by accumulation of glucosylceramide in lysosomes due to mutations in the GBA1 gene encoding the lysosomal hydrolase β-glucocerebrosidase (GCase). The disease has a broad spectrum of phenotypes, which were divided into three different Types; Type 1 GD is not associated with primary neurological disease while Types 2
Bendikov-Bar, Inna, Maor, Gali, Filocamo, Mirella, Horowitz, Mia   +3 more
openaire   +3 more sources

Meta analysis of curative effect and safety of different doses of ambroxol for lung cancer patients in perioperative period

Huli yanjiu, 2015
To systematically assess the curative effect and safety of different doses of ambroxol for lung cancer patients in perioperative period.Methods:The randomised or quasi-randomized controlled trials RCTs) on the application of different doses of ambroxol ...
冯莉, 王爱平
doaj  

Mucolytic therapy of ARD in pregnant women

Медицинский совет, 2013
Acute respiratory disease (ARD) is one of the most common pathologies in pregnant women. During their pregnancy, about 2/3 of women suffer from one or several episodes of ARD of any severity.
R. A. Bontsevich, O. V. Golovchenko
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Efficacy of Ambroxol Combined with Loquat Syrup on Bacterial Pneumonia in Mice

Journal of Inflammation Research
Chenping Li, Zhi Chen, Jiaqi Shi, Xiuyun Zheng Department of Pulmonary and Critical Care Medicine (PCCM), The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People’s Republic of ChinaCorrespondence: Xiuyun Zheng ...
Li C, Chen Z, Shi J, Zheng X
doaj  

Ambroxol hydrochloride spray (Luo Runchang®) in the treatment of acute respiratory infectious diseases: a prospective, multicenter, open label, randomized controlled study

Frontiers in Pediatrics
PurposeCough and sputum are the most common clinical symptoms of acute respiratory tract infection. Ambroxol is a mucolytic expectorant commonly used in clinical practice.
Lu Cheng, Min Liu, Rong Wang, Sufen Cao, Rui Li, Bo Su, Hongyan Wei, Haijuan Yang, Lingyun Hou, Chunyu Geng, Yuling Han, Tianrui Yang   +11 more
doaj   +1 more source