Results 51 to 60 of about 8,299 (247)
VALIDATION METHOD OF ULTRAVIOLET SPECTROPHOTOMETRY DETERMINATION OF CONTENT IN AMBROXOL HCl TABLET
Jurnal Natural, 2015 Ambroxol Hydrochloride (Ambroxol HCI) is one of mucolytic drugs that is commonly used to dilute thesecretion within the respiratory tract. This process is completed by lowering the viscosity of mucopolysaccharides, in which its characteristic which is ...
Tedy Kurniawan Bakri +3 more
doaj +2 more sources
Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential [PDF]
, 2015 Autophagy is a conserved homeostatic process active in all human cells and affecting a spectrum of diseases. Here we use a pharmaceutical screen to discover new mechanisms for activation of autophagy.
Ahmed, Zahra +16 more
core +3 more sources
Use of Ambroxol as Therapy for Gaucher Disease
JAMA Network Open, 2023 ImportanceAmbroxol was identified as an enhancer of stability and residual activity of several misfolded glucocerebrosidase variants in 2009.ObjectivesTo assess hematologic and visceral outcomes, biomarker changes, and safety of ambroxol therapy for patients with Gaucher disease (GD) without disease-specific treatment.Design, Setting, and ...
Zhan, Xia +6 more
openaire +2 more sources
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Foix‐Chavany‐Marie Syndrome (FCMS), also known as opercular syndrome, is a rare neurological disorder caused by an ischemic stroke that results in autonomic‐voluntary dissociation. In this case report, we describe a patient who presented with an acute right frontal and parietal cortical lesion, in addition to a remote infarction in the left ...
Lu Xia +7 more
wiley +1 more source
Molecular Genetics and Metabolism Reports, 2019 Type 3 Gaucher disease (GD3) is characterized by progressive neurological features in addition to the typical systemic manifestations. Enzyme replacement therapy (ERT), the main stay treatment for Gaucher disease (GD), is not efficacious for the ...
Behshad Charkhand +4 more
doaj +1 more source
Ambroxol effects in glucocerebrosidase and -synuclein transgenic mice [PDF]
, 2016 Objective. Gaucher disease is caused by mutations in the glucocerebrosidase 1 gene that result in deficiency of the lysosomal enzyme glucocerebrosidase.
Bezard, E +3 more
core
Analysis of the evidence of efficacy and safety of over-the-counter cough medications registered in Brazil [PDF]
, 2010 The objective of this study was to analyze the level of evidence regarding the efficacy, effectiveness and safety of over-the-counter (OTC) cough medications registered in Brazil.
FIGUERAS, Albert +1 more
core +4 more sources
Journal of Research in Medical Sciences, 2020 Background: Paraquat (PQ) poisoning is characterized by rapidly progressive acute poisoning with high mortality and no specific antidote. Although some clinical studies have been conducted to investigate the benefits of high-dose ambroxol as an adjuvant ...
Junwu Wang +4 more
doaj +1 more source
Drug-induced anaphylaxis in China: a 10 year retrospective analysis of the Beijing Pharmacovigilance Database [PDF]
, 2017 Background Few studies on the causes of drug-induced anaphylaxis (DIA) in the hospital setting are available. Objective We aimed to use the Beijing Pharmacovigilance Database (BPD) to identify the causes of DIA in Beijing, China.
Li, Xiaotong +7 more
core +1 more source
Development of a new ultra-high performance liquid chromatography - tandem mass spectrometry method for determination of ambroxol hydrochloride in serum with pharmacokinetic application [PDF]
Hemijska Industrija, 2016 Ambroxol hydrochloride is an expectorant agent, successfully applied in mucolytic therapy for acute and chronic bronchopulmonary diseases. The drug regulates not only mucus secretion but also showed antioxidant, anti-inflammatory and local ...
Vujović Maja M. +2 more
doaj +1 more source