Results 11 to 20 of about 1,461 (159)

Genomic characterization of the T-cell receptor loci in Ambystoma mexicanum [PDF]

Frontiers in Immunology
BackgroundAmphibians are valuable models for comparative immunology. In the caudate Ambystoma mexicanum, the architecture of immunoglobulin loci resembles that of the anuran Xenopus tropicalis, although some antibody gene features are absent.
Diana L. Pacheco-Olvera, Diana L. Pacheco-Olvera, Stephanie Saint Remy-Hernández, Stephanie Saint Remy-Hernández, E. Ernestina Godoy-Lozano, Juan Téllez-Sosa, Humberto Valdovinos-Torres, Everado Curiel-Quesada, Constantino López-Macías, Jesus Martínez-Barnetche   +9 more
doaj   +2 more sources

Identification and Functional Characterization of the Axolotl (Ambystoma mexicanum) Tau Protein [PDF]

Alzheimers Dement
Abstract Background Tauopathies are characterized by abnormal aggregation of tau that results in neuronal dysfunction and degeneration. Developing strategies to preserve existing neuronal function, prevent neurodegeneration, or restore lost neurons may have the most potential to combat human tauopathy; however, the adult human brain possesses limited ...
Strickland Z, Giasson B, Lewis J.
europepmc   +2 more sources

Histological image data of limb skeletal tissue from larval and adult Ambystoma mexicanum [PDF]

Data in Brief, 2016
The data presented in this article are related to the article entitled “Cartilage and bone cells do not participate in skeletal regeneration in Ambystoma mexicanum limbs” [1].
Catherine D. McCusker, Carlos Diaz-Castillo, Julian Sosnik, Anne Phan, David M. Gardiner   +4 more
doaj   +2 more sources

Regeneration of limb joints in the axolotl (Ambystoma mexicanum). [PDF]

PLoS ONE, 2012
In spite of numerous investigations of regenerating salamander limbs, little attention has been paid to the details of how joints are reformed. An understanding of the process and mechanisms of joint regeneration in this model system for tetrapod limb ...
Jangwoo Lee, David M Gardiner
doaj   +6 more sources

Exploring Larval Axolotl Brain Development: Insights Into Developmental and Functional Constraints. [PDF]

Evol Dev
We studied brain shape and volume variations during larval development of the Mexican axolotl. Modularity, morphological integration, and allometric regressions supported both mosaic and concerted evolution models, highlighting a complex interplay of constraints during axolotl ontogeny.
Houle L, Larouche O, Cloutier R.
europepmc   +2 more sources

Tyrp1 is the mendelian determinant of the Axolotl (Ambystoma mexicanum) copper mutant [PDF]

Scientific Reports
Several dozen Mendelian mutants have been discovered in axolotl (Ambystoma mexicanum) populations, including several that affect pigmentation. Four recessive mutants have been described in the scientific literature and genes for three of these have been ...
Raissa F. Cecil, Lloyd Strohl, Maddie K. Thomas, James L. Schwartz, Nataliya Timoshevskaya, Jeramiah J. Smith, S. Randal Voss   +6 more
doaj   +2 more sources

Establishment of a Practical Sperm Cryopreservation Pathway for the Axolotl (Ambystoma mexicanum): A Community-Level Approach to Germplasm Repository Development [PDF]

Animals
The axolotl (Ambystoma mexicanum) draws great attention around the world for its importance as a biomedical research model, but housing and maintaining live animals is increasingly expensive and risky as new transgenic lines are developed.
Nicholas Coxe, Yue Liu, Lucía Arregui, Rose Upton, Sarah Bodenstein, Steven Randal Voss, Maria T. Gutierrez-Wing, Terrence R. Tiersch   +7 more
doaj   +2 more sources

Identification of antimicrobial peptides from the Ambystoma mexicanum displaying antibacterial and antitumor activity. [PDF]

PLoS ONE
Antibiotic resistance is a significant healthcare concern. Therefore, identifying target molecules that can serve as antibiotic substitutes is crucial. Among the promising candidates are antimicrobial peptides (AMPs).
Nadjib Dastagir, Christina Liebsch, Jaqueline Kutz, Sabine Wronski, Andreas Pich, Doha Obed, Peter Maria Vogt, Vesna Bucan, Sarah Strauß   +8 more
doaj   +2 more sources

Systemic and local lipid adaptations underlie regeneration in Drosophila melanogaster and Ambystoma mexicanum [PDF]

npj Regenerative Medicine
In regenerating tissues, synthesis and remodeling of membranes rely on lipid turnover and transport. Our study addresses lipid adaptations in intestinal regeneration of Drosophila melanogaster and limb regeneration of Ambystoma mexicanum.
Ines C. Kübler, Jenny Kretzschmar, Maria Nieves Arredondo-Lasso, Sean D. Keeley, Luca Claudia Rößler, Katharina Ganss, Tatiana Sandoval-Guzmán, Marko Brankatschk   +7 more
doaj   +2 more sources

Experiences with the management and breeding of Mexican axolotl (Ambystoma mexicanum), for research and biobanking purposes, in a vivarium

Frontiers in Amphibian and Reptile Science
The Mexican axolotl (Ambystoma mexicanum) is widely used in laboratory research around the world, even though it is classified as critically endangered in nature. We review and describe the development of effective management strategies for this species,
Erika Servín, Erika Servín, Alicia Alcantar-Rodriguez, Alfredo Medrano   +3 more
exaly   +3 more sources