Results 41 to 50 of about 1,461 (159)
Transforming Life Science Through Chromosome‐Level Genome Assemblies
Genes to Cells, Volume 31, Issue 5, September 2026.Chromosome‐level genome assemblies provide a framework for “glocal biology” in species of interest, linking local molecular features to chromosome architecture and evolutionary context. When integrated with pangenome analysis, comparative multi‐omics, genome language models, and experimental approaches, these assemblies enable hypothesis generation and
Tetsuo Kon +7 more
wiley +1 more source
FEBS Open Bio, Volume 16, Issue 8, Page 1477-1490, August 2026.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
GnRH Protein Levels in Atrazine-Treated Axolotls (Ambystoma mexicanum) [PDF]
Impulse: The Premier Undergraduate Neuroscience Journal, 2008 Atrazine is the most widely used agricultural herbicide in the United States and a known endocrine disruptor. In amphibians, it has been shown to cause gonadal malformations, feminization of males, behavioral changes, and immune suppression; however, its
Sarah Leupen, Sara Nienaber
doaj
The Anatomical Record, Volume 309, Issue 8, Page 2151-2175, August 2026.Abstract Scientists have been captivated by the ability to regenerate, focusing on uncovering the mechanisms of epimorphic regeneration and applying them to human medicine. The axolotl (Ambystoma mexicanum) has become the most intensively studied model in tetrapod regeneration research, particularly concerning limb regeneration.
Vivien Bothe, Nadia Fröbisch
wiley +1 more source
Revisiting the relationship between regenerative ability and aging
BMC Biology, 2013 Contrary to the longstanding view that newts (Notophthalamus viridescens), but not axolotls (Ambystoma mexicanum), can regenerate a lens, a recent report in BMC Biology by Panagiotis Tsonis and colleagues shows axolotls indeed possess this ability during
Seifert Ashley W, Voss S
doaj +1 more source
Advanced Science, Volume 13, Issue 41, 22 July 2026.We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu +11 more
wiley +1 more source
Multiplex CRISPR/Cas screen in regenerating haploid limbs of chimeric Axolotls
eLife, 2020 Axolotls and other salamanders can regenerate entire limbs after amputation as adults, and much recent effort has sought to identify the molecular programs controlling this process.
Lucas D Sanor +2 more
doaj +1 more source
Replace, reduce, refine: A review of animal use in Batrachochytrium salamandrivorans research
Conservation Science and Practice, Volume 8, Issue 7, July 2026.Abstract Animal experimentation is common in wildlife disease research. Understanding the impact of this often‐lethal approach is therefore a critical line of inquiry at the intersection of animal welfare and conservation biology. The discovery of the pathogenic salamander chytrid fungus Batrachochytrium salamandrivorans (Bsal) in 2013 ignited a large ...
Alexandra Boren +2 more
wiley +1 more source
Divergent Influenza-Like Viruses of Amphibians and Fish Support an Ancient Evolutionary Association
Viruses, 2020 Influenza viruses (family Orthomyxoviridae) infect a variety of vertebrates, including birds, humans, and other mammals. Recent metatranscriptomic studies have uncovered divergent influenza viruses in amphibians, fish and jawless vertebrates, suggesting ...
Rhys Parry +4 more
doaj +1 more source
Streptozotocin induced hyperglycemia in the axolotl
Developmental Dynamics, Volume 255, Issue 6, Page 567-584, June 2026.Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen +2 more
wiley +1 more source