Results 51 to 60 of about 1,461 (159)
Polysialic acid (PSA), a homopolymer attached to neural cell adhesion molecule (NCAM) is considered a major hallmark of vertebrate cell migration. We studied the distribution of PSA-NCAM by immunohistochemistry, during brain development, in two urodele ...
S Gianola, P Clairambault, MF Franzoni
doaj +1 more source
SpatialESD: Spatial Ensemble Domain Detection in Spatial Transcriptomics
ABSTRACT Spatial transcriptomics (ST) measures gene expression while preserving spatial context within tissues. One of the key tasks in ST analysis is spatial domain detection, which remains challenging due to the complex structure of ST data and the varying performance of individual clustering methods. To address this, we propose SpatialESD, a Spatial
Hongyan Cao +11 more
wiley +1 more source
Abstract A pet axolotl (Ambystoma mexicanum) from Tuscany (Italy) presented with small, whitish, elongated structures attached to the neck region and abdominal flanks and was in poor general clinical condition. The structures were identified as belonging to the genus Lernaea (commonly called ‘anchor worm’), crustacean copepods that commonly parasitise ...
Lisa Guardone +4 more
wiley +1 more source
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino +3 more
wiley +1 more source
An approach for elucidating dermal fibroblast dedifferentiation in amphibian limb regeneration
Urodele amphibians, Pleurodeles waltl and Ambystoma mexicanum, have organ-level regeneration capability, such as limb regeneration. Multipotent cells are induced by an endogenous mechanism in amphibian limb regeneration.
Akira Satoh +7 more
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Dynamic expression of lamin B1 during adult neurogenesis in the vertebrate brain
Abstract Background In mammals, specific brain regions such as the dentate gyrus (DG) of the hippocampus and the subventricular zone (SVZ) of the lateral ventricles harbor adult neural stem/progenitor cells (ANSPCs) that give rise to new neurons and contribute to structural and functional brain plasticity.
Diana Zhilina +12 more
wiley +1 more source
Dorsoventral-mediated Shh induction is required for axolotl limb regeneration
Axolotls (Ambystoma mexicanum) exhibit a remarkable ability to regenerate limbs. Classical experiments have suggested that contact between cells derived from distinct orientations—dorsal, ventral, anterior, and posterior—within the regenerating blastema ...
Sakiya Yamamoto +4 more
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Abstract Modularity and integration are key developmental properties and have remained central in evo‐devo research because of how they relate to evolvability. While modularity and integration have commonly been assessed with landmark‐based geometric morphometrics (GMM), other methods such as anatomical network analysis (AnNA) are increasingly being ...
Kevin K. Duclos +4 more
wiley +1 more source
Like other urodela amphibians, axolotls are able to regenerate lost appendages, even as adults, rendering them unique among higher vertebrates. In reaction to the severe trauma of a lost limb, apoptosis seems to be primarily implicated in the removal of ...
Vesna Bucan +5 more
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Proteome data to explore the axolotl limb regeneration capacity at neotenic and metamorphic stages
The presented data article reports protein expression profiles during a time course of limb regeneration in the highly regenerative neotenic and regeneration-deficient metamorphic axolotl (Ambystoma mexicanum). A protein database was first generated from
Turan Demircan +2 more
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