Results 131 to 140 of about 291,669 (391)

Reconfigurable Microenvironments Uncover Mechano‐Sensing Timescales and Direct Cell Polarity

open access: yesAdvanced Functional Materials, EarlyView.
A synthetic DNA‐crosslinked cell culture matrix enables control over the mechanical microenvironment surrounding cells. Independent tuning of stiffness and stress relaxation uncovers distinct timescales of mechano‐sensing that regulate cell behavior.
Syuan‐Ku Hsiao   +4 more
wiley   +1 more source

Biotransformation of xenobiotics by mycelium of Laricifomes officinalis (Polyporales, Basidiomycota)

open access: yesUkrainian Botanical Journal
Laricifomes officinalis is known for producing biologically active pharmaceuticals. This species belongs to wood-decay fungi capable of biotransforming various xenobiotics. Despite this potential, the ability of L.
Bondaruk S.V.   +2 more
doaj   +1 more source

Selective C-N σ Bond Cleavage in Azetidinyl Amides under Transition Metal-Free Conditions

open access: yesMolecules, 2019
Functionalization of amide bond via the cleavage of a non-carbonyl, C-N σ bond remains under-investigated. In this work, a transition-metal-free single-electron transfer reaction has been developed for the C-N σ bond cleavage of N ...
Hengzhao Li   +4 more
doaj   +1 more source

The fate of certain organic acids and amides in the rabbit [PDF]

open access: green, 1948
H. G. Bray   +4 more
openalex   +1 more source

VANILLYL-ACYL AMIDES. [PDF]

open access: yesJournal of the American Chemical Society, 1919
n ...
openaire   +3 more sources

Self‐Immolative Activatable Nanoassembly toward Immuno‐Photodynamic Therapy in TME

open access: yesAdvanced Functional Materials, EarlyView.
A quinone methide‐gated, self‐immolative, H2O2‐responsive nano‐photosensitizer (Pyz/PS) is developed for targeted immuno‐photodynamic therapy. Pyz/PS selectively activates within tumor microenvironments, restores photosensitizer activity, generates ROS, and depletes intracellular GSH, enhancing oxidative stress.
Jing Li   +10 more
wiley   +1 more source

Practical and Metal-Free Synthesis of Novel Enantiopure Amides Containing the Potentially Bioactive 5-Nitroimidazole Moiety

open access: yesMolecules, 2016
We report here a practical and metal-free synthesis of novel enantiopure amides containing the drug-like 5-nitroimidazole scaffold. The first step was a metal-free diastereoselective addition of 4-(4-(chloromethyl)phenyl)-1,2-dimethyl-5-nitro-1H ...
Cédric Spitz   +4 more
doaj   +1 more source

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

open access: yesAdvanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz   +3 more
wiley   +1 more source

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