Results 11 to 20 of about 174,959 (338)

para-Selective C-H amidation of simple arenes with nitriles [PDF]

, 2015
A para-selective C-H amidation of simple arenes with nitriles has been developed. By increasing the amount of arenes, a further meta-selective C-H arylation of the produced amides occurred.
Allen, Allen, Antonchick, Casitas, Chen, Fañanás-Mastral, Gao, Grohmann, Guérinot, Harvey, He, He, Hsieh, Huffman, Ichiishi, Ichiishi, Kantak, Kawano, Kim, Kim, King, Li, Li, Louillat, Lv, Marchetti, Matsuda, Nadres, Ng, Ng, Ng, Ng, Peng, Phipps, Phipps, Pialat, Ryu, Ryu, Shai, Shin, Shrestha, Skucas, Sokolovs, Su, Tew, Thomas, Thu, Tran, Tsang, Valeur, Wang, Wang, Wang, Xiang, Xu, Yoo, Zhang, Zhang, Zhang, Zhao   +59 more
core   +2 more sources

Nickel-catalyzed transamidation of aliphatic amide derivatives. [PDF]

, 2017
Transamidation, or the conversion of one amide to another, is a long-standing challenge in organic synthesis. Although notable progress has been made in the transamidation of primary amides, the transamidation of secondary amides has remained ...
Baker, Emma L, Dander, Jacob E, Garg, Neil K   +2 more
core   +1 more source

A two-step approach to achieve secondary amide transamidation enabled by nickel catalysis. [PDF]

, 2016
A long-standing challenge in synthetic chemistry is the development of the transamidation reaction. This process, which involves the conversion of one amide to another, is typically plagued by unfavourable kinetic and thermodynamic factors. Although some
Anthony, Sarah M, Baker, Emma L, Garg, Neil K, Yamano, Michael M, Zhou, Yujing   +4 more
core   +2 more sources

Towards energetically viable asymmetric deprotonations : selectivity at more elevated temperatures with C2-symmetric magnesium bisamides [PDF]

, 2011
A novel chiral magnesium bisamide has enabled the development of effective asymmetric deprotonation protocols at substantially more elevated temperatures.
Aggarwal, Alexakis, Allan, Allan J. B. Watson, Anderson, Aoki, Aoki, Aoki, Aoki, Bassindale, Blümke, Brownbridge, Brownbridge, Bunn, Bunn, Bunn, Busch-Petersen, Carswell, Clegg, Conway, Corey, Cousins, Eaton, Eaton, Graf, Graf, Gronnow, Hama, Henderson, Henderson, Henderson, Henderson, Henderson, Hodgson, Ila, Kerr, Kerr, Kerr, Knochel, Leitner, Linsey S. Bennie, Melzig, Michael Middleditch, Mulvey, Navarro, Netherton, Sato, Shirai, Shirai, Simpkins, Simpkins, Westerhausen, William J. Kerr, Wunderlich, Çalimsiz   +54 more
core   +1 more source

[1,5]-Hydride Shift Triggered N-Dealkylative Cyclization into 2-Oxo-1,2,3,4-tetrahydroquinoline-3-carboxylates via Boronate Complexes

Molecules, 2022
A new simple one-pot two-step protocol for the synthesis of 2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate from 2-(2-(benzylamino)benzylidene)malonate under the action of BF3·Et2O was developed.
Elvira R. Zaitseva, Dmitrii S. Ivanov, Alexander Yu. Smirnov, Andrey A. Mikhaylov, Nadezhda S. Baleeva, Mikhail S. Baranov   +5 more
doaj   +1 more source

Asymmetric synthesis of γ-chloro-α,β-diamino- and β,γ-aziridino-α-aminoacylpyrrolidines and -piperidines via stereoselective Mannich-type additions of N-(diphenylmethylene)glycinamides across α-chloro-N-sulfinylimines [PDF]

, 2012
The asymmetric synthesis of new chiral gamma-chloro-alpha,beta-diaminocarboxylamide derivatives by highly diastereoselective Mannich-type reactions of N-(diphenylmethylene) glycinamides across chiral alpha-chloro-N-p-toluenesulfinylaldimines was ...
Augustyns, Koen, Callebaut, Gert, De Kimpe, Norbert, Mangelinckx, Sven, Tornroos, Karl W, Van der Veken, Pieter   +5 more
core   +3 more sources

A Self-Immolative Linker for the pH-Responsive Release of Amides

Molecules, 2023
The administration of therapeutics using bioconjugation has been mainly limited to drugs containing amine, alcohol, or thiol functional groups. Here, we report a general procedure for the preparation of benzylic N-acyl carbamates suitable for masking the
Agnese Petrini, Giovanni Ievoli, Francesca Migliorini, Maurizio Taddei, Sofia Siciliano   +4 more
doaj   +1 more source

Thermoresponsive poly(2-oxazoline)s, polypeptoids, and polypeptides [PDF]

, 2017
This review covers the recent advances in the emerging field of thermoresponsive polyamides or polymeric amides, i.e., poly(2-oxazoline)s, polypeptoids, and polypeptides, with a specific focus on structure-thermoresponsive property relationships, self ...
Hoogenboom, Richard, Schlaad, Helmut
core   +2 more sources

AMIDES ISOLATED FROM THE LEAVES OF Piper tuberculatum Jacq. (Piperaceae) WITH ACETYLCHOLINESTERASE INHIBITION AND LARVICIDAL ACTIVITY AGAINST Aedes aegypti [PDF]

Química Nova
Piper tuberculatum Jacq. is known to be a promising source of amides, which have shown remarkable biological activities. In this study, a phytochemical investigation of the leaves of P.
Brenda R. C. Leocadio, Taynara S. Vale, Felipe M. A. da Silva, João V. C. O. Santos, Sergio M. Nunomura, André C. de Oliveira, Ingrity S. C. Sá, Rosemary A. Roque, Ana Paula A. Castro, Magno P. Muniz, Rita C. S. Nunomura   +10 more
doaj   +1 more source

Bioactive Compounds from P. pertomentellum That Regulate QS, Biofilm Formation and Virulence Factor Production of P. aeruginosa

Molecules, 2023
Pseudomonas aeruginosa is an opportunistic pathogen responsible for many nosocomial infections. This bacterium uses Quorum Sensing (QS) to generate antimicrobial resistance (AMR) so its disruption is considered a novel approach.
Lida V. Hernández-Moreno, Ludy C. Pabón-Baquero, Juliet A. Prieto-Rodriguez, Oscar J. Patiño-Ladino   +3 more
doaj   +1 more source