Results 71 to 80 of about 291,669 (391)
A Self-Immolative Linker for the pH-Responsive Release of Amides
Molecules, 2023 The administration of therapeutics using bioconjugation has been mainly limited to drugs containing amine, alcohol, or thiol functional groups. Here, we report a general procedure for the preparation of benzylic N-acyl carbamates suitable for masking the
Agnese Petrini +4 more
doaj +1 more source
Enzyme‐Catalysed Synthesis of Secondary and Tertiary Amides
Advanced Synthesis and Catalysis, 2019 The synthesis of the amide bond between an amine and a carboxylic acid is one of the most significant reactions in industrial pharmaceutical synthesis.
M. Petchey, G. Grogan
semanticscholar +1 more source
Advanced Biology, EarlyView.Amide local anesthetics (LA) affect tumor burden in various preclinical studies, possibly via their anti‐inflammatory properties. However, a translation into clinical evidence is still lacking. The current study demonstrates that LA ‐ even at clinically relevant concentrations – exert a strong anti‐tumoral effect in a complex ex vivo model patient ...
Juliane Krömer +8 more
wiley +1 more source
Synthesis of methylenebisamides using CC- or DCMT-activated DMSO
Beilstein Journal of Organic Chemistry, 2008 Bisamides are key fragments for the introduction of gem-diaminoalkyl residues into retroinverso pseudopeptide derivatives and in the synthesis of peptidomimetic compounds. The literature methods for these types of compounds have certain drawbacks.
Qiang Wang +3 more
doaj +1 more source
Synthesis of indoles via alkylidenation of acyl hydrazides [PDF]
, 2009 Indoles have been synthesised via alkylidenation of acyl phenylhydrazides using phosphoranes and the Petasis reagent, followed by in situ thermal rearrangement of the product enehydrazines.
Commeureuc, A.G.J. +5 more
core +1 more source
Advanced Engineering Materials, EarlyView.Mesoporous bioactive glass nanoparticles (MBGNs) are investigated for bone regeneration given their remarkable structural and functional properties. MBGNs are functionalized with Mn and Cu and incorporated with quercetin, a natural flavonoid exhibiting antioxidant, anti‐inflammatory, and antimicrobial properties.
Giovanni Lo Bello +5 more
wiley +1 more source
대한영상의학회지, 2016 Amide proton transfer (APT) imaging is gaining attention as a relatively new in vivo molecular imaging technique that has higher sensitivity and spatial resolution than magnetic resonance spectroscopy imaging.
Ji Eun Park, Geon-Ho Jahng, Ha-Kyu Jeong
doaj +1 more source
Advanced Engineering Materials, EarlyView.Lithium‐mediated electrocatalysis enables sustainable N2 fixation but hindered by parasitic Li deposition. An oxide‐oxide nanocomposite (LiVO3/LiZnVO4) structurally integrates lithium into active sites, suppressing plating and enhancing N2 activation and HER supression.
Naina Goyal +4 more
wiley +1 more source
Frontiers in Pharmacology, 2018 Datura metel L. is a widely used traditional herbal medicine, and withanolides and amides are the two groups of main bioactive constituents in Datura metel seeds.
Silun Xu +7 more
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Thermally Induced Gelling Systems Based on Patchy Polymeric Micelles
Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.A novel strategy to design thermally induced gelling systems with tunable material properties is reported. Polymeric mixed‐shell micelles displaying multiple thermosensitive patchy domains formed hydrogels by assembling into well‐entangled worm‐like network structures upon heating to body temperature. The patchy micelle design significantly affects the
Binru Han +9 more
wiley +1 more source