Results 71 to 80 of about 159,996 (294)
Advanced Healthcare Materials, EarlyView.This study presents a novel implantable drug delivery systemwith a biodegradable poly(caprolactone) membrane and compressed drug core forsustained release. These implantable devices deliver risperidone in vitro for 170 days and in vivo for 49 days in rats, showing promise for chronic conditions like schizophrenia.
Linlin Li +9 more
wiley +1 more source
Synthesis of C-5" and C-6"-modified α-GalCer analogues as iNKT-cell agonists [PDF]
, 2015 Alpha-Galactosyl Ceramide (α-GalCer) is a prototypical synthetic ligand of invariant natural killer T (iNKT) cells. Upon presentation by the MHC class I-like molecule CD1d, this glycolipid stimulates iNKT cells to secrete a vast amount of both pro ...
ASPESLAGH, SANDRINE +5 more
core +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman +6 more
wiley +1 more source
Diisopropylamide and TMP turbo-grignard reagents : a structural rationale for their contrasting reactivities [PDF]
, 2010 A neutral dimeric molecule in crystal form, the diisopropylamido turbo-Grignard reagent "(iPr2N)MgCl⋅LiCl" (see structure; blue N, red O, green Mg, yellow Cl, black C) separates into several charged ate species in dynamic exchange with each other in THF ...
Armstrong, David R. +4 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Biomimetic glycosaminoglycan analog hydrogels exhibit suitable and robust mechanical properties, as well as hemocompatibility and biocompatibility, making them ideal for the embolization of intracranial aneurysms. Notably, the hydrogel's environment‐selective swelling properties enable complete blockage of the aneurysm cavity while preventing ...
Sarit S. Sivan +8 more
wiley +1 more source
Biologically Active Compounds. II. The Synthesis of β-CarboxY-γ-butyrolactone Derivatives [PDF]
, 1968 Amide derivatives of γ-substituted paraconic and aconic acids have been synthesized. Ultraviolet spectra of the aconic acid derivatives showed characteristic fine structure in the region of 245 to 280 ...
Isikawa, Tatsuo +2 more
core +1 more source
Pyrophosphate‐Containing Calcium Phosphates Negatively Impact Heterotopic Bone Quality
Advanced Healthcare Materials, EarlyView.The role of calcium pyrophosphate (Ca‐PP) in heterotopic bone formation and material degradation is investigated using calcium phosphate (CaP) compositions with varying Ca‐PP content. Results show that Ca‐PP does not impede heterotopic bone formation, minimally affects CaP degradation at non‐osseous sites, and increases phagocytosis.
Martina Jolic +7 more
wiley +1 more source
The fate of certain organic acids and amides in the rabbit. 6. Nitrobenzoic acids and amides [PDF]
, 1949 H. G. Bray +2 more
openalex +1 more source
Silylation of Carbohydrate Syrups [PDF]
, 1979 Introduction Carbohydrates are usually difficult to analyze in solutions. Gas chromatography provides a suitable means for analysis. However most carbohydrate compounds are not volatile enough for use by this method.
Gorwitz, Mark
core +1 more source
Advanced Healthcare Materials, EarlyView.Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang +8 more
wiley +1 more source