Results 51 to 60 of about 10,322 (256)
Continuous-Flow Synthesis of Thioureas, Enabled by Aqueous Polysulfide Solution
Molecules, 2021 We have developed the continuous-flow synthesis of thioureas in a multicomponent reaction starting from isocyanides, amidines, or amines and sulfur. The aqueous polysulfide solution enabled the application of sulfur under homogeneous and mild conditions.
András Gy. Németh +5 more
doaj +1 more source
Nitrogen-bound diazeniumdiolated amidines [PDF]
Chemical Communications, 2010 In contrast to amidines bearing ionizable alpha-CH bonds, which react with nitric oxide (NO) to add diazeniumdiolate groups at their alpha-carbons, benzamidine forms an N-bound diazeniumdiolate that can be further derivatized at the other amidine nitrogen and/or the terminal oxygen to form caged NO compounds as potential NO prodrugs.
Debanjan, Biswas +3 more
openaire +2 more sources
Studies on the Interaction of Isocyanides with Imines: Reaction Scope and Mechanistic Variations [PDF]
, 2018 The interaction of imines with isocyanides has been studied. The main product results from a sequential process involving the attack of two units of isocyanide, under Lewis acid catalysis, upon the carbon-nitrogen double bond of the imine to form the 4 ...
Ghashghaei, Ouldouz +4 more
core +1 more source
Molecules, 2007 A series of novel benzimidazole derivatives 3-10 were synthesized. Benzimidazolyl-substituted acrylonitriles 3 and 4 underwent a photochemical dehydrocyclization reaction to give the corresponding mono- and dicyano-substituted benzimidazo[1,2-a ...
Marijana Hranjec, Grace Karminski-Zamola
doaj +1 more source
Synthesis of Fully Substituted Pyrimidines [PDF]
, 2016 A novel approach to the synthesis of fully substituted pyrimidine derivatives armed with an oxy-functionalized acetate chain at the ring is described. The manifold uses amidines as the nitrogen source and activated skipped diynes as the electrophilic
García-Tellado, Fernando +2 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Zinc‐containing bioactive glass (ZnBG) promotes diabetic wound healing by regulating macrophage extracellular traps (METs). Specifically, ZnBG reduces oxidative stress and inhibits the PAD4 and NLRP3/caspase‐1/GSDMD signaling pathways, thereby suppressing MET formation.
RuiYang Sun +11 more
wiley +1 more source
Regiochemistry of cyclocondensation reactions in the synthesis of polyazaheterocycles
Beilstein Journal of Organic Chemistry, 2017 The syntheses of several polyazaheterocycles are demonstrated. The cyclocondensation reactions between β-enaminodiketones [CCl3C(O)C(=CNMe2)C(O)-CO2Et] and aromatic amidines resulted in glyoxalate-substituted pyrido[1,2-a]pyrimidinone, thiazolo[3,2-a ...
Patrick T. Campos +10 more
doaj +1 more source
(E)-N-[Cyclopentyl(morpholin-4-yl)methylidene]-4-fluorobenzenesulfonamide
IUCrData, 2016 The title compound, C16H21FN2O3S, was obtained from the reaction between sulfonyl azide, cyclohexanone and morpholine. The bond lengths at the amidine N—C—N grouping are similar [1.326 (3) and 1.338 (3) Å], indicating significant conjugation.
Ilya Efimov +3 more
doaj +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
1,3-Dipolar Cycloaddition (Part II): Three-Component Cu(I) Catalysed Click Reactions [PDF]
Kemija u Industriji, 2015 The Cu(I) catalysed reaction of sulfonyl or phosphoryl azide and terminal alkyne obtains a ketenimine intermediate that reacts with nucleophiles like water, alcohols, amines, imines, pyrroles or indoles producing corresponding amides, imidates, amidines ...
Krstulović L. +4 more
doaj +1 more source