Results 31 to 40 of about 4,376 (210)

Preclinical in vitro screening of newly synthesised amidino substituted benzimidazoles and benzothiazoles

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2021
Newly synthesised benzimidazole/benzotiazole derivatives bearing amidino, namely 3,4,5,6-tetrahydropyrimidin-1-ium chloride, substituents have been evaluated for their potential antitumor activity in vitro.
Livio Racané   +6 more
doaj   +1 more source

Influence of Steric Effect on the Pseudo-Multicomponent Synthesis of N-Aroylmethyl-4-Arylimidazoles

open access: yesMolecules, 2022
A pseudo-three-component synthesis of N-aroylmethylimidazoles 3 with three new C–N bonds formed regioselectively under microwave conditions was developed.
Nerith Rocio Elejalde-Cadena   +5 more
doaj   +1 more source

Three-Component Reaction of Tautomeric Amidines with 3-Ferrocenylmethylidene-2,4-pentanedione. Formation of Polymeric Coordination Complexes of Potassium Ferrocenyl-(hexahydro)pyrimidoxides

open access: yesMolecules, 2013
Acetamidine hydrochloride and p-aminobenzamidine dihydrochloride interact with 3-ferrocenylmethylidene-2,4-pentanedione at 80–82 °C in the presence of K2CO3 in the water–alcohol medium in two tautomeric forms (the amidoimine and enediamine ones) with ...
Elena I. Klimova   +4 more
doaj   +1 more source

Synthesis of Amidines and Its Application to Pyrimidouracil Synthesis

open access: yes, 2020
An efficient and sustainable copper-catalyzed protocol has been developed for the preparation of amidines via nucleophilic addition of amines into nitriles.
Pradip Debnath
core   +1 more source

Acaricide resistance of Rhipicephalus decoloratus ticks collected from communal grazing cattle in South Africa

open access: yesJournal of Advanced Veterinary and Animal Research, 2022
Objective: This study aimed to determine acaricide resistance in Rhipicephalus decoloratus ticks collected from grazing cattle between November 2018 and May 2019 in Elundini, Senqu, and Walter Sisulu Local Municipalities in the northeastern region of the
Mandla Yawa   +4 more
doaj   +1 more source

Synthetic studies towards bottromycin

open access: yesBeilstein Journal of Organic Chemistry, 2012
Thio-Ugi reactions are described as an excellent synthetic tool for the synthesis of sterically highly hindered endothiopeptides. S-Methylation and subsequent amidine formation can be carried out in an inter- as well as in an intramolecular fashion.
Stefanie Ackermann   +4 more
doaj   +1 more source

Electrocatalytic Polarity Inversion of Azlactones: Access to α‐Quaternary Amino Acids with Electron‐Rich SOMOphiles

open access: yesAngewandte Chemie, Volume 138, Issue 42, 12 October 2026.
Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez   +6 more
wiley   +2 more sources

Quantitative determination of 0.05 % chlorhexidine solution by capillary electrophoresis

open access: yesZaporožskij Medicinskij Žurnal, 2019
The aim of the work was to estimate the quantitative content of 0.05 % chlorhexidine solution by capillary electrophoresis. Materials and methods.
A. M. Sampiiev   +3 more
doaj   +1 more source

Chiral Cyclic Amidines

open access: yes, 1994
Cyclic amidines are prepared in 3 steps from an aromatic aldehyde, isobutyraldehyde, and urea.
Ten Hoeve, Wolter   +3 more
core   +1 more source

Properties of Amidinated Glucagons [PDF]

open access: yesEuropean Journal of Biochemistry, 1980
Porcine glucagon has been reacted with a series of alkyl imidates. The ɛ‐amino group and both the α and ɛ‐amino groups were modified and the subsequent glucagon derivatives were purified by ion‐exchange chromatography and characterized. The modified glucagons were compared with native glucagon in their ability to activate hepatic adenylate cyclase and ...
D E, Wright, M, Rodbell
openaire   +2 more sources

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