Results 11 to 20 of about 3,968 (220)

Iron-catalyzed [4 + 2] annulation of amidines with α,β-unsaturated ketoxime acetates toward 2,4,6-trisubstituted pyrimidines

Green Synthesis and Catalysis, 2023
An iron-catalyzed [4 ​+ ​2] annulation of amidines with α,β-unsaturated ketoxime acetates is described. This strategy employs amidines as CN units and provides a new protocol for the construction of 2,4,6-trisubstituted pyrimidines under batch and ...
Qinghuan Wu, Jindian Duan, Kai Guo
exaly   +3 more sources

An isofagomine analogue with an amidine group in the 1,6-position [PDF]

Royal Society Open Science
The synthesis of an isofagomine analogue with an amidine group in the 1,6-position is described. Density functional theory calculations showed that this compound has a remarkably different charge distribution compared with isofagomine.
I. Caroline Vaaland Holmgard, Idd Andrea Christensen, Ljupcho Pejov, Monika Moreń, Nikolai Westlund, Tereza Cristina Santos Evangelista, Magne O. Sydnes, Finn L. Aachmann, Óscar López, Emil Lindbäck   +9 more
doaj   +2 more sources

Nucleophilic Addition Reactions to 10-Acetonitrilium Derivative of nido-Carborane and Intramolecular NH⋯HB Interactions in N-Alkyl Amidines 10-RNHC(Me)=NH-7,8-C₂B₉H₁₁ [PDF]

Molecules
The addition reactions of water, alcohols, and primary and secondary amines to the 10-acetonitrilium derivative of nido-carborane were studied. Hydrolysis of 10-MeC≡N-7,8-C2B9H11 results in iminol 10-MeC(OH)=HN-7,8-C2B9H11, which, on treatment with a ...
Kirill R. Pakholkov, Ekaterina V. Bogdanova, Marina Yu. Stogniy, Kyrill Yu. Suponitsky, Sergey A. Anufriev, Igor B. Sivaev, Vladimir I. Bregadze   +6 more
doaj   +2 more sources

Synthesis and Reactivity of Ynamine Amidines

CHIMIA, 1976
Ynamine amidines can be synthesized from the 1,3-dichlorotrimethine cyanine and primary amines. Ammonia affords the reactive ynamine amidine having a free imino group. This compound cyclises readily with carbon dioxide and phenylisocyanate.
B. Caillaux, P. George, F. Tataruch, Z. Janousek, H.G. Viehe   +4 more
doaj   +3 more sources

Innovative Syntheses and Reactivity of Propiolamidines [PDF]

Molecules
Polydentate ligands with nitrogen donor atoms have possibly given rise to the largest group of coordination complexes described. Among these ligands, amidinates represent a nitrogenated version of carboxylates and allow the formation of complexes with ...
Carlos Ginés, Blanca Parra-Cadenas, Fernando Carrillo-Hermosilla, David Elorriaga   +3 more
doaj   +2 more sources

Copper-Catalyzed Aerobic [3+2]-Annulation of N-Alkenyl Amidines

, 2016
A method for the synthesis of bi- and tricyclic amidines has been developed through copper-catalyzed aerobic [3+2]-annulation reaction of N-alkenyl amidines.
Shunsuke Chiba (1670473), Xu Zhu (424407), Yi-Feng Wang (529972)   +2 more
core   +6 more sources

Hypotheses for synthesis of novel chiral beta-amino-beta-lactams through amidines

Results in Chemistry, 2021
Synthesis of new beta-lactams is an attractive field because some of these types of molecules are biologically active. The design and preparation of C4-nitrogen-substituted beta-lactams are not known.
Bimal Krishna Banik, Alberto Boretti
doaj   +1 more source

Cascade Transformations of 1-R-Ethynyl-9,10-anthraquinones with Amidines: Expanding Access to Isoaporphinoid Alkaloids

Molecules, 2021
The interaction of acetamidine and phenylamidine with peri-R-ethynyl-9,10-anthraquinones in refluxing n-butanol leads to the formation of cascade transformations products: addition/elimination/cyclization―2-R-7H-dibenzo[de,h]quinolin-7-ones and(or) 2-R-3-
Sergey Francevich Vasilevsky, Ol’ga Leonidovna Krivenko, Irina Vasilievna Sorokina, Dmitry Sergeevich Baev, Tatyana Genrikhovna Tolstikova, Igor V. Alabugin   +5 more
doaj   +1 more source

Hydrogen-bonding behavior of amidines in helical structure. [PDF]

Chem Sci
Amidines are an isostere of the amide bond and are completely unexplored in peptide secondary structure. This study marks the first investigation of the structural implications of amidines in folded helices.
O'Brien EA, Purslow JA, Wall BJ, VanVeller B.   +3 more
europepmc   +2 more sources

Synthesis of Cyclic N-Acyl Amidines by [3 + 2] Cycloaddition of N-Silyl Enamines and Activated Acyl Azides

Molecules, 2022
In this study, we describe the synthesis of cyclic N-acyl amidines from readily available N-heteroarenes. The synthetic methodology utilized the versatile N-silyl enamine intermediates from the hydrosilylation of N-heteroarenes for the [3 + 2 ...
Dong Geun Jo, Changeun Kim, Sinjae Lee, Sooyeon Yun, Seewon Joung   +4 more
doaj   +1 more source