Results 21 to 30 of about 4,376 (210)

Hydrogen-bonding behavior of amidines in helical structure. [PDF]

Chem Sci
Amidines are an isostere of the amide bond and are completely unexplored in peptide secondary structure. This study marks the first investigation of the structural implications of amidines in folded helices.
O'Brien EA, Purslow JA, Wall BJ, VanVeller B.   +3 more
europepmc   +2 more sources

Principais métodos de síntese de amidinas

Química Nova, 2006
The amidine functional group is found in a wide range of natural products and is biologically active against several pathogens. In addition, amidines have long been regarded as useful intermediates in the synthesis of heterocyclic compounds. Consequently,
Maurício Silva dos Santos, Alice Maria Rolim Bernardino, Marcos Costa de Souza   +2 more
doaj   +1 more source

Conflict of interest:use of pyrethroids and amidines against tsetse and ticks in zoonotic sleeping sickness endemic areas of Uganda [PDF]

, 2013
Caused by trypanosomes and transmitted by tsetse flies, Human African Trypanosomiasis and bovine trypanosomiasis remain endemic across much of rural Uganda where the major reservoir of acute human infection is cattle.
Welburn Susan C., Katie Hampson, Waiswa, Charles, Sambo, Maganga, Bardosh, Kevin, Welburn, Susan C, Susan C Welburn, Maganga Sambo, Sikana Lwitiko, Hampson, Katie, Bardosh Kevin, Hampson Katie, Kevin Bardosh, Lwitiko Sikana, Sikana, Lwitiko, Welburn, Susan C., Sambo Maganga, Bardosh, Kevin Louis   +17 more
core   +1 more source

Copper-Catalyzed One-Pot Synthesis of N-Sulfonyl Amidines from Sulfonyl Hydrazine, Terminal Alkynes and Sulfonyl Azides

Molecules, 2021
N-Sulfonyl amidines are developed from a Cu-catalyzed three-component reaction from sulfonyl hydrazines, terminal alkynes and sulfonyl azides in toluene at room temperature.
Yu Zhao, Zitong Zhou, Man Chen, Weiguang Yang   +3 more
doaj   +1 more source

Efficient Copper Catalyzed Multi-component Synthesis of N-acyl amidines via Acyl Nitrenes [PDF]

, 2019
Direct synthetic routes to amidines are desired, as they are widely present in many biologically active compounds and organometallic complexes. N-Acyl amidines in particular can be used as a starting material for the synthesis of heterocycles and have ...
Maxime A., Siegler, K.M., van Vliet, J.I., van der Vlugt, Célia Fonseca, Guerra, Lara H., Polak, Bas, de Bruin   +5 more
core   +2 more sources

Synthesis and Biological Evaluation of Amidinourea Derivatives against Herpes Simplex Viruses

Molecules, 2021
Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antivirals such as acyclovir, famciclovir and valacyclovir. However, the current drugs are ineffective against latent and drug-resistant HSV infections.
Anita Toscani, Rossana Denaro, Sergio Fernando Castillo Pacheco, Matteo Biolatti, Silvia Anselmi, Valentina Dell’Oste, Daniele Castagnolo   +6 more
doaj   +1 more source

Amidine Dications as Superelectrophiles

Journal of the American Chemical Society, 2009
2-Dimethylalkylammonium pyridinium and 2-dimethylalkylammonium pyrimidinium ditriflate salts are very powerful methylating agents toward phosphorus (triphenylphosphine) and nitrogen (triethylamine) nucleophiles. In competition experiments with triethylamine as nucleophile, these N-methyl disalts are more reactive methylating agents than dimethyl ...
Corr, Michael J, Roydhouse, Mark D, Gibson, Kirsty F, Zhou, Sheng-Ze, Kennedy, Alan R, Murphy, John A   +5 more
openaire   +4 more sources

Susceptibility of Amblyomma sculptum, Vector of Rickettsia rickettsii, Ticks from a National Park and an Experimental Farm to Different Synthetic Acaricides

Pathogens, 2023
Amblyomma sculptum is a relevant tick species from a One Health perspective, playing an important role as a vector of Rickettsia rickettsii, the main agent of spotted fever rickettsiosis in Brazil. In this study, we evaluated the susceptibility of two A.
Ennya Rafaella Neves Cardoso, Stephani Félix Carvalho, Sarah Alves Dias, Rayane Almeida Santos, Mariana Avelar Tavares, Lucianne Cardoso Neves, Warley Vieira de Freitas Paula, Gracielle Teles Pádua, Nicolas Jalowitzki de Lima, Raquel Loren dos Reis Paludo, Isabela Santos Silva, Raphaela Bueno Mendes Bittencourt, Gabriel Cândido dos Santos, Flavia Giovana de Jesus Nascimento, Luiza Gabriella Ferreira de Paula, Filipe Dantas-Torres, Caio Marcio De Oliveira Monteiro, Felipe da Silva Krawczak   +17 more
doaj   +1 more source

Biological Activity of Newly Synthesized Benzimidazole and Benzothizole 2,5-Disubstituted Furane Derivatives

Molecules, 2021
Newly designed and synthesized cyano, amidino and acrylonitrile 2,5-disubstituted furane derivatives with either benzimidazole/benzothiazole nuclei have been evaluated for antitumor and antimicrobial activity.
Livio Racané, Ivo Zlatar, Nataša Perin, Maja Cindrić, Vedrana Radovanović, Mihailo Banjanac, Suresh Shanmugam, Marijana Radić Stojković, Karmen Brajša, Marijana Hranjec   +9 more
doaj   +1 more source

Biological Activity of Amidino-Substituted Imidazo [4,5-b]pyridines

Molecules, 2022
A series of cyano- and amidino-substituted imidazo[4,5-b]pyridines were synthesized using standard methods of organic synthesis, and their biological activity was evaluated.
Ida Boček Pavlinac, Katarina Zlatić, Leentje Persoons, Dirk Daelemans, Mihajlo Banjanac, Vedrana Radovanović, Kristina Butković, Marijeta Kralj, Marijana Hranjec   +8 more
doaj   +1 more source