Results 1 to 10 of about 10,518 (175)

Revisiting D‐Acylases for D‐Amino Acid Production [PDF]

Microbial Biotechnology
N‐Acyl‐D‐amino acid deacylases (EC 3.5.1.81, also known as D‐acylases) have been studied for decades for their utility in the kinetic resolution of N‐acetyl‐D,L‐amino acids (NAAs) due to a marked stereospecificity. In conjunction with an N‐succinyl‐amino
Sergio Martínez‐Rodríguez, Jose Antonio Gavira   +1 more
doaj   +2 more sources

Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron [PDF]

, 2015
The amidohydrolase superfamily has remarkable functional diversity, with considerable structural and functional annotation of known sequences. In microbes, the recent evolution of several members of this family to catalyze the breakdown of environmental ...
Carr, Paul D., Fraser, Nicholas J., Hopkins, Davis H., Jackson, Colin J., Khurana, Jeevan L., Nojiri, H., Oakeshott, John G., Scott, Colin, Sugrue, Elena   +8 more
core   +3 more sources

Bacterial amidohydrolases and modified 5-fluorocytidine compounds: Novel enzyme-prodrug pairs. [PDF]

PLoS ONE, 2023
Gene-directed enzyme prodrug therapy is an emerging strategy for cancer treatment based on the delivery of a gene that encodes an enzyme that is able to convert a prodrug into a potent cytotoxin exclusively in target cancer cells.
Viktorija Preitakaitė, Povilas Barasa, Agota Aučynaitė, Gediminas Plakys, Martyna Koplūnaitė, Simona Zubavičiūtė, Rolandas Meškys   +6 more
doaj   +2 more sources

Allantoate Amidohydrolase OsAAH is Essential for Preharvest Sprouting Resistance in Rice [PDF]

Rice
Preharvest sprouting (PHS) is an undesirable trait that decreases yield and quality in rice production. Understanding the genes and regulatory mechanisms underlying PHS is of great significance for breeding PHS-resistant rice.
Ting Xie, Wenling Hu, Jiaxin Shen, Jiangyu Xu, Zeyuan Yang, Xinyi Chen, Peiwen Zhu, Mingming Chen, Sunlu Chen, Hongsheng Zhang, Jinping Cheng   +10 more
doaj   +2 more sources

Probing the enzymatic activity and maturation process of the EcAIII Ntn-amidohydrolase using local random mutagenesis [PDF]

Acta Biochimica Polonica
This report describes a comprehensive approach to local random mutagenesis of the E. coli Ntn-amidohydrolase EcAIII, and supplements the results published earlier for the randomization series RDM1.
Joanna I. Loch, Anna Ściuk, Anna Ściuk, Marta Kilichowska, Marta Kilichowska, Izabela Pieróg, Izabela Pieróg, Weronika Łukaszczyk, Katarzyna Zimowska, Mariusz Jaskolski, Mariusz Jaskolski   +10 more
doaj   +2 more sources

Safety evaluation of the food enzyme asparaginase from the non‐genetically modified Saccharomyces cerevisiae strain ARY‐2 [PDF]

EFSA Journal
The asparaginase (L‐asparagine amidohydrolase, EC 3.5.1.1) is produced by the non‐genetically modified Saccharomyces cerevisiae strain ARY‐2 by Renaissance BioScience Corporation.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Henk Van Loveren, Laurence Vernis, Cristina Fernàndez‐Fraguas, Daniele Cavanna, Silvia Peluso, Yi Liu   +16 more
doaj   +2 more sources

Exploring the Effect and Molecular Docking Interaction of Carboxypeptidase and Amidohydrolase on Ochratoxin A and Zearalenone Degradation

BioResources
To keep consumers from the hazard of exposure to mycotoxins and meet the allowed limits, numerous physical and chemical approaches for eliminating Ochratoxin A (OTA) and Zearalenone (ZEN) have been studied.
Sulaiman A. Alsalamah, Mohammed Ibrahim Alghonaim, Abdu Ali Y. Moafa, Mukul Sharma   +3 more
doaj   +2 more sources

Safety evaluation of the food enzyme asparaginase from the non‐genetically modified Saccharomyces cerevisiae strain ARY‐1 [PDF]

EFSA Journal
The asparaginase (l‐asparagine amidohydrolase, EC 3.5.1.1) is produced by the non‐genetically modified Saccharomyces cerevisiae strain ARY‐1 by Renaissance BioScience Corporation.
EFSA Panel on Food Enzymes (FEZ), Holger Zorn, José Manuel Barat Baviera, Claudia Bolognesi, Francesco Catania, Gabriele Gadermaier, Ralf Greiner, Baltasar Mayo, Alicja Mortensen, Yrjö Henrik Roos, Marize L. M. Solano, Monika Sramkova, Henk Van Loveren, Laurence Vernis, Jaime Aguilera, Daniele Cavanna, Cristina Fernàndez‐Fraguas, Yi Liu   +17 more
doaj   +2 more sources

Metarhizium spp. encode an ochratoxin cluster and a high efficiency ochratoxin-degrading amidohydrolase revealed by genomic analysis [PDF]

Journal of Advanced Research
Introduction: Ochratoxins (OTs) are worldwide regulated mycotoxins contaminating a variety of food-environment and agro-environment. Several Aspergillus and Pencillium species synthesize OTs from a six-gene biosynthetic gene cluster (BGC) to produce the ...
Gang Wang, Wenqing Wu, Nancy P. Keller, Xu Guo, Erfeng Li, Junning Ma, Fuguo Xing   +6 more
doaj   +2 more sources

The Pseudomonas aeruginosa Type VI secretion system toxin Tse8 evolved from a novel N-carbamoylputrescine amidohydrolase. [PDF]

Biochem J
Li B, Baniasadi HR, Phillips MA, Michael AJ.   +3 more
europepmc   +2 more sources