Results 11 to 20 of about 5,660 (180)

Crystal structure of carbon-nitrogen hydrolase from Helicobacter pylori G27. [PDF]

Acta Crystallogr F Struct Biol Commun
H. pylori carbon–nitrogen hydrolase was produced and crystallized, and its 2.1 Å resolution structure is reported.Carbon–nitrogen hydrolases (CNHs) are members of the diverse nitrilase superfamily of enzymes that facilitate cellular adaptation to environmental stress by metabolizing nitrogen, detoxifying xenobiotics and catabolizing environmentally ...
Srivastava A, Ayanlade JP, Suleiman L, Udell H, Abendroth J, Lorimer DJ, Edwards TE, Staker BL, Zigweid R, Subramanian S, Myler PJ, Chakafana G, Asojo OA.   +12 more
europepmc   +2 more sources

Safety evaluation of the food enzyme glutaminase from the genetically modified <i>Bacillus subtilis</i> strain Glu3-3. [PDF]

EFSA J
Abstract The food enzyme glutaminase (l‐glutamine amidohydrolase; EC 3.5.1.2) is produced with the genetically modified Bacillus subtilis strain Glu3‐3 by Angel Yeast Co., Ltd. The production strain of the food enzyme contains multiple copies of acquired antimicrobial resistance genes.
EFSA Panel on Food Enzymes (FEZ), Zorn H, Barat Baviera JM, Bolognesi C, Catania F, Gadermaier G, Greiner R, Mayo B, Mortensen A, Roos YH, Solano MLM, Van Loveren H, Vernis L, Aguilera J, Andryszkiewicz M, Cavanna D, Liu Y.   +16 more
europepmc   +2 more sources

Thermotolerant D-Hydantoinases for Efficient and Stereoselective Intermediate Synthesis of (R)-3-Isobutylglutaric Acid Monoamide, a Key Intermediate in Pregabalin Production. [PDF]

Microb Biotechnol
We engineered thermo‐alkali‐stable D‐hydantoinases via mutagenesis (M63A/F65H/C317T) to resolve Pregabalin's challenging chiral splitting, achieving ee value > 97% for key intermediate (R)‐3‐isobutylglutaric acid monoamide (R‐IBM) synthesis under extreme conditions (pH 10, 70°C–80°C).
Zhang J, Zhi B, Xie Z, Zhang B, Wang N, Wang W.   +5 more
europepmc   +2 more sources

Penicillin Amidohydrolases in Fungal Autolysis [PDF]

Microbiology and Immunology, 1989
AbstractThe production of penicillin G and penicillin V amidohydrolases or acylases (E.C.3.5.1.11) was studied during the autolysis of filamentous fungi in a mineral medium, and in the same medium with phenoxyacetic acid as inducer. In all the studied fungi, enzymes showing penicillin G and penicillin V amidohydrolase activities were found.
C, Alfonso, L, Cribeiro, F, Reyes
openaire   +2 more sources

Structure of the Ergothioneine‐Biosynthesis Amidohydrolase EgtC [PDF]

ChemBioChem, 2015
AbstractThe ubiquitous sulfur metabolite ergothioneine is biosynthesized by oxidative attachment of a sulfur atom to the imidazole ring of Nα‐trimethylhistidine. Most actinobacteria, including Mycobacterium tuberculosis, use γ‐glutamyl cysteine as a sulfur donor. In subsequent steps the carbon scaffold of γ‐glutamyl cysteine is removed by the glutamine
Vit, Allegra, Mashabela, Gabriel, Blankenfeldt, Wulf, Seebeck, Florian P.   +3 more
openaire   +5 more sources

Dynamics of Jasmonate Metabolism upon Flowering and across Leaf Stress Responses in Arabidopsis thaliana

Plants, 2016
The jasmonic acid (JA) signaling pathway plays important roles in adaptation of plants to environmental cues and in specific steps of their development, particularly in reproduction.
Emilie Widemann, Ekaterina Smirnova, Yann Aubert, Laurence Miesch, Thierry Heitz   +4 more
doaj   +1 more source

Phenoxymethylpenicillin amidohydrolases from Penicillium chrysogenum [PDF]

FEBS Letters, 1996
A phenoxymethylpenicillin amidohydrolase which hydrolyses phenoxymethylpenicillin to 6‐aminopenicillanic acid (6‐APA) has been isolated from two species of Penicillium chrysogenum. The amidohydrolase had a molecular mass of approx. 42 kDa. Its activity with benzylpenicillin as substrate was only 1.5% of that with phenoxymethylpenicillin and it was ...
Whiteman, P.A., Abraham, E.P.
openaire   +2 more sources

N-Carbamoylputrescine Amidohydrolase of Bacteroides thetaiotaomicron, a Dominant Species of the Human Gut Microbiota

Biomedicines, 2023
Polyamines are bioactive amines that play a variety of roles, such as promoting cell proliferation and protein synthesis, and the intestinal lumen contains up to several mM polyamines derived from the gut microbiota.
Hiromi Shimokawa, Mikiyasu Sakanaka, Yuki Fujisawa, Hirokazu Ohta, Yuta Sugiyama, Shin Kurihara   +5 more
doaj   +1 more source

N-acylsphingosine amidohydrolase 1 promotes melanoma growth and metastasis by suppressing peroxisome biogenesis-induced ROS production

Molecular Metabolism, 2021
Objective: Metabolic deregulation is a key hallmark of cancer cells and has been shown to drive cancer growth and metastasis. However, not all metabolic drivers of melanoma are known.
Parmanand Malvi, Radoslav Janostiak, Arvindhan Nagarajan, Xuchen Zhang, Narendra Wajapeyee   +4 more
doaj   +1 more source

EFFECT OF PHYTOHORMONES ON UREASE ACTIVITY OF MARROW COTYLEDONS [PDF]

Journal of Plant Production, 2009
Urease (EC 3.5.1.5, urea amidohydrolase) was isolated from marrow cotyledons of 5-day old seedlings. The effect of exogenous phytohormones namely indolebutyric acid, naphthaleneacetic acid, indoleacetic acid, indolepropionic acid, indoleacetic acid and ...
Lamiaa El Said, H. El-Shora
doaj   +1 more source