Results 101 to 110 of about 10,587 (231)

On the role of Cys150 in the mechanism of maleamate amidohydrolase (NicF)

The FASEB Journal, 2012
The oxidative degradation of nicotinate (vitamin B3) to fumarate is considered a model system for the bacterial degradation of N‐heterocyclic compounds, yet only recently has the complete set of genes corresponding to the enzymes involved in this pathway been identified.
Nicholas E. Spittle, Mark J. Snider, Jeff W. Noel   +2 more
openaire   +1 more source

Non‐human primate models of Parkinson's disease: Decoding pathogenesis and advancing therapies

Brain‐X, Volume 3, Issue 2, June 2025.
Parkinson's disease ranks as the second most prevalent neurodegenerative disorder, and there is an urgent need for proper experimental models to enhance our understanding of this complex disease. Non‐human primates exhibit various similarities to humans, particularly in terms of motor skills, cognitive functions, and the complexity of their neural ...
Sihui Zhang, Lin Yuan, Zihan Wu, Xuguang Du, Jacek Z. Kubiak, Feng Yue, Xuejing Yan, Gaolin Jiang, Yongye Huang   +8 more
wiley   +1 more source

Expression, purification and characterisation of recombinant peptide:N-glycosidase F. : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Biochemistry at Massey University [PDF]

, 2000
PNGase F (Peptide-N4-(N-acetyl-D-glucosaminyl) asparagine amidase F) is an amidohydrolase isolated from the extracellular medium of the Gram-negative bacterium Flavobacterium meningosepticum.
Loo, Trevor Stephen
core  

Systematic Analysis of Gene Expression Differences between Left and Right Atria in Different Mouse Strains and in Human Atrial Tissue [PDF]

, 2011
Background: Normal development of the atria requires left-right differentiation during embryonic development. Reduced expression of Pitx2c (paired-like homeodomain transcription factor 2, isoform c), a key regulator of left-right asymmetry, has recently ...
Brown, NA, Fabritz, L, Greber, B, Hoffmeier, A, Kahr, PC, Kirchhof, P, Piccini, I, Scheld, HH, Schöler, H   +8 more
core   +3 more sources

Discovering leaf and stripe rust resistance in soft red winter wheat through genome‐wide association studies

The Plant Genome, Volume 18, Issue 2, June 2025.
Abstract Leaf rust (LR) and stripe rust (YR), which are caused by Puccinia triticina and Puccinia striiformis, respectively, are among the most devastating wheat rusts worldwide. These diseases can be managed by using genetically resistant cultivars, an economical and environmentally safer alternative to fungicides. Over 100 and 80 Lr and Yr resistance
John W. Bagwell, Mohamed Mergoum, Madhav Subedi, Suraj Sapkota, Bikash Ghimire, Benjamin Lopez, James W. Buck, Bochra A. Bahri   +7 more
wiley   +1 more source

LncR-GAS5 decrease in adenine phosphoribosyltransferase expresssion via binding TAF1 to increase kidney damage created by CIH

Heliyon
Objective: Chronic kidney disease (CKD) related to obstructive sleep apnea-hypopnea syndrome (OSAHS) mainly results from chronic intermittent hypoxia (CIH)-induced renal injury.
Wei Liu, Wukaiyang Liang, CunTai Zhang, Huiguo Liu, Hai Li, Lun Zhou, Ling Zhou   +6 more
doaj   +1 more source

Isolation and screening of l-asparaginase free of glutaminase and urease from fungal sp. [PDF]

, 2016
l-Asparaginase is a chemotherapeutic drug used in the treatment of acute lymphoblastic leukaemia (ALL), a malignant disorder in children. l-Asparaginase helps in removing acrylamide found in fried and baked foods that is carcinogenic in nature.
Devarai, Santhosh Kumar, Doriya, K
core   +1 more source

Identification of a candidate gene for a QTL for spikelet number per spike on wheat chromosome arm 7AL by high-resolution genetic mapping. [PDF]

, 2019
Key messageA high-resolution genetic map combined with haplotype analyses identified a wheat ortholog of rice gene APO1 as the best candidate gene for a 7AL locus affecting spikelet number per spike.
Akhunov, Eduard, Anderson, James A, Bai, Guihua, Brown-Guedira, Gina, DeWitt, Noah, Dubcovsky, Jorge, Faris, Justin D, Fraser, Max, Katz, Andrew, Kuzay, Saarah, Pearce, Stephen, Peters Haugrud, Amanda, Su, Zhenqi, Xu, Yunfeng, Zhang, Junli   +14 more
core   +1 more source

Transposon mutagenesis in a hyper-invasive clinical isolate of Campylobacter jejuni reveals a number of genes with potential roles in invasion [PDF]

, 2010
Transposon mutagenesis has been applied to a hyper-invasive clinical isolate of Campylobacter jejuni, 01/51. A random transposon mutant library was screened in an in vitro assay of invasion and 26 mutants with a significant reduction in invasion were ...
Bagnall, MC, Grant, AJ, Javed, MA, Manning, G, Maskell, DJ, Newell, DG   +5 more
core   +1 more source

The structure of the hexameric atrazine chlorohydrolase AtzA

, 2015
Atrazine chlorohydrolase (AtzA) was discovered and purified in the early 1990s from soil that had been exposed to the widely used herbicide atrazine. It was subsequently found that this enzyme catalyzes the first and necessary step in the breakdown of ...
Balotra, S., Lucent, D., Newman, J., Peat, T. S., Scott, C., Warden, A. C.   +5 more
core   +1 more source