Allantoate Amidohydrolase OsAAH is Essential for Preharvest Sprouting Resistance in Rice
RicePreharvest sprouting (PHS) is an undesirable trait that decreases yield and quality in rice production. Understanding the genes and regulatory mechanisms underlying PHS is of great significance for breeding PHS-resistant rice.
Ting Xie +10 more
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Expression, purification and characterisation of recombinant peptide:N-glycosidase F. : a thesis presented in partial fulfilment of the requirements for the degree of Master of Philosophy in Biochemistry at Massey University [PDF]
, 2000 PNGase F (Peptide-N4-(N-acetyl-D-glucosaminyl) asparagine amidase F) is an amidohydrolase isolated from the extracellular medium of the Gram-negative bacterium Flavobacterium meningosepticum.
Loo, Trevor Stephen
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On the Origin of Substrate Specificity of Enzymes from the Amidohydrolase Superfamily
Angewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.Comprehensive analyses of two enzyme classes from the amidohydrolase superfamily (AHS) revealed that catalysis proceeds either via 1,4 or 1,6 nucleophilic conjugate addition and that this property defines substrate specificity. Moreover, although all substrates and products are entirely achiral, this mechanistic difference results in an inverted ...
Lukas Drexler +3 more
wiley +1 more source
HeliyonObjective: Chronic kidney disease (CKD) related to obstructive sleep apnea-hypopnea syndrome (OSAHS) mainly results from chronic intermittent hypoxia (CIH)-induced renal injury.
Wei Liu +6 more
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Decoding Urease Inhibition: A Comprehensive Review of Inhibitor Scaffolds
ChemMedChem, Volume 21, Issue 2, January 2026.Representative functional groups known for urease inhibition are reviewed within diverse scaffolds using structure–activity analyses to identify features associated with high inhibitory activity. Urease is a metalloenzyme produced by a wide range of organisms and plays a critical role in nitrogen microbial metabolism by catalyzing the hydrolysis of ...
Nuno Martinho, Natália Aniceto
wiley +1 more source
iScienceSummary: The 5′-deoxyadenosine deaminase (DADD), a member of the amidohydrolase family regulates biological purine metabolism. In this study, bioinformatic analysis, overexpression and knockdown of GhdadD gene were detected to identify its potential role
Yuanyuan Zhang +11 more
doaj +1 more source
Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography [PDF]
, 2007 Soil bacteria that also form mutualistic symbioses in plants encounter two major levels of selection. One occurs during adaptation to and survival in soil, and the other occurs in concert with host plant speciation and adaptation. Actinobacteria from the
Alloisio, Nicole +19 more
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The structure of the hexameric atrazine chlorohydrolase AtzA
, 2015 Atrazine chlorohydrolase (AtzA) was discovered and purified in the early 1990s from soil that had been exposed to the widely used herbicide atrazine. It was subsequently found that this enzyme catalyzes the first and necessary step in the breakdown of ...
Balotra, S. +5 more
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Overexpression of acid ceramidase (ASAH1) protects retinal cells (ARPE19) from oxidative stress[S]
Journal of Lipid Research, 2019 Over 11 million people in the United States alone have some form of age-related macular degeneration (AMD). Oxidative stress, cell death, and the degeneration of retinal pigment epithelial (RPE) cells contribute to AMD pathology. Recent evidence suggests
Eriko Sugano +9 more
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The role of two families of bacterial enzymes in putrescine synthesis from agmatine via agmatine deiminase [PDF]
, 2011 Putrescine, one of the main biogenic amines associated to microbial food spoilage, can be formed by bacteriafrom arginine via ornithine decarboxylase (ODC), or from agmatine via agmatine deiminase (AgDI).
Isabel Pardo +4 more
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