Results 121 to 130 of about 205,880 (261)

Amikacin Dosing for MDR Tuberculosis: A Systematic Review to Establish or Revise the Current Recommended Dose for Tuberculosis Treatment.

Clinical Infectious Diseases, 2018
Background Amikacin has been used for over 40 years in multidrug resistant tuberculosis (MDR-TB), but there is still debate on the right dose. The aim of this review was to search relevant pharmacokinetic (PK) and pharmacodynamic (PD) literature for the ...
M. Sturkenboom, Noviana Simbar, O. Akkerman, S. Ghimire, M. Bolhuis, J. Alffenaar   +5 more
semanticscholar   +1 more source

Laboratory Analysis of Fecal Lactobacillus Strains and pH in Tobacco Smokers: A Comparative Study From a Developing Country

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Tobacco smoking is a major cause of preventable mortality globally, disproportionately impacting developing countries. While its systemic health effects are well‐known, the influence of tobacco on gut microbiota—especially beneficial Lactobacillus species—remains poorly explored in resource‐limited settings.
Afshin Shabibi, Gholam Basati, Bahareh Rahimian Zarif, Kambiz Davari, Alireza Rangin   +4 more
wiley   +1 more source

Molecular Mechanisms of Resistance and Treatment Efficacy of Delamanid Against Mycobacterium tuberculosis: A Systematic Review

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aims Tuberculosis (TB) remains a major global health problem, and treatment progress is increasingly threatened by rising multidrug‐resistant tuberculosis (MDR‐TB). Delamanid (DLM), a nitroimidazole drug, has shown good efficacy and safety against both drug‐susceptible and drug‐resistant Mycobacterium tuberculosis (Mtb) strains.
Md. Mahmudul Islam, Md. Zahid Hasan, Md. Touki Tahamid Tusar, Md. Yeamin Hossain, Md. Motaher Hossain, Md. Abdulla Al Jubayed, Md. Jubaer‐Al‐Abedin, Sheikh Soikot, Shanzida Akther, Jahid Bhuyian, Hafizur Rahman Gazi, B. M. Mahmudul Hasan, Md. Shofiul Azam, Md. Enamul Haque, Abdullah‐Al‐Jubayer, Md. Faruk Hasan, F. M. Ali Haydar, Md. Khalekuzzaman, Md. Torequl Islam, Sohel Hasan   +19 more
wiley   +1 more source

Optimal Amikacin Levels for Patients with Sepsis in Intensive Care Unit of Cipto Mangunkusumo Hospital, Jakarta, Indonesia

Acta Medica Indonesiana, 2017
Background: Amikacin is one of the antibiotics of choice for sepsis and septic shock. Pharmacokinetic of amikacin can be influenced by septic condition with subsequent effect on its pharmacodynamic.
Gestina Aliska, Rianto Setiabudi, purwantyastuti purwantyastuti, Anis Karuniawati, Rudyanto Sedono, Trisni U Dewi, Muhammad K Azwar   +6 more
doaj  

Carvacrol attenuates amikacin-induced nephrotoxicity in the rats

Recent Trends in Pharmacology
Objective: Amikacin (AK) is a wide-spectrum antibiotic routinely used to treat gram-negative and some gram-positive bacterial infections. However, its use is limited due to its potential to cause nephrotoxicity due to an increase in reactive oxygen ...
Cemil Çolak, Ahmet Sefa Duman, Yılmaz Çiğremiş, Atta Mohammad Dost, Selahattin Tunç, Nigar Vardı, Azibe Yıldız, Onural Özhan, Hakan Parlakpınar, Mehmet Günata   +9 more
doaj   +1 more source

Phenolic Compounds: From Traditional Uses to Innovative Applications and Everything in Between

Molecular Nutrition &Food Research, Volume 70, Issue 9, 13 May 2026.
This review deals with many aspects related to the study of phenolic compounds, starting with advances in extraction, detection, and quantification methods, going through bioavailability, bioactivity, and beneficial health properties, and discussing antioxidant and antimicrobial uses and mechanisms.
Marcela de Sá Barreto da Cunha, Cristina Maria Turim Santos Miguel, Emília Maria França Lima, Uelinton Manoel Pinto, Cláudia Vieira Prudêncio, Svetoslav Dimitrov Todorov   +5 more
wiley   +1 more source

Antibiotic Sensitivity Testing and Molecular Characteristics Related to Clarithromycin and Amikacin Resistance in Mycobacterium abscessus Complex Isolated from Patients with Pulmonary Infection at National Hospital 74, Vietnam

International Journal of Mycobacteriology
Background: Mycobacterium abscessus complex (MABC) is an important cause of opportunistic infections in the respiratory tracts. Data on antimicrobial resistance of MABC in Vietnam were still lacking. Methods: From December 2021 to July 2022, mycobacteria
Vu Thi Thuong, Bui Thi Thanh Nga, Le Thi Lan Anh, Nguyen Van Doai, Nguyen Minh Phuong, Luu Van Doan, Pham Viet Hung   +6 more
doaj   +1 more source

Isolation, Identification and Pathogenicity Analysis of Proteus mirabilis in Cynomolgus Monkey From Yunnan, China

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
This study demonstrated that the pathogen responsible for diarrhoea in a cynomolgus monkey was identified as Proteus mirabilis (P. mirabilis) through methods including bacterial isolation and culture, morphological examination, biochemical profiling, 16S rRNA sequencing, analysis of key virulence genes and bacterial artificial infection tests.
Heling Li, Ziyao Qian, Lan Luo, Xinglong Chen, Baohong Tian, Zhigang Chen, Hong Wang   +6 more
wiley   +1 more source

Incidence of Acute Kidney Injury in Autologous Hematopoietic Stem Cell Transplant Recipients According to the Administration of Empirical Amikacin: A Two-Centre Retrospective Cohort Study

Antibiotics
Background: The benefit of adjunctive aminoglycosides in the treatment of patients with febrile neutropenia (FN) is controversial. We investigated the incidence of acute kidney injury (AKI) in patients with FN or suspected infection according to ...
Sophie Schürch, Sarah Dräger, Michèle Hoffmann, Severin Bausch, Nicolas Gürtler, Cédric Hirzel, Jakob Passweg, Stefano Bassetti, Thomas Pabst, Parham Sendi, Michael Osthoff   +10 more
doaj   +1 more source

Nanoscopic evaluation to facilitate treatment of the proximal interphalangeal joint following a traumatic wound in a 4‐month‐old colt

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 4‐month‐old Irish Draught colt was presented for treatment of a traumatic wound to the right hind pastern region of 6 hours’ duration. Investigation confirmed communication between the wound and the proximal interphalangeal joint. Due to the joint's small size, a traditional synovial endoscopic lavage could not be performed.
Jarred Green, John David Stack, Constance Bowkett‐Pritchard, Louise J. Breen, Alexandra Gillen   +4 more
wiley   +1 more source