Results 111 to 120 of about 162,947 (233)

MT‐RNR1 genotype testing for preventing aminoglycoside‐mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, Volume 92, Issue 9, Page 3002-3011, September 2026.
Aminoglycosides are broad‐spectrum antibiotics used in the management of severe infections. Aminoglycosides are associated with nephrotoxicity and ototoxicity. Although dosing strategies such as once‐daily administration and therapeutic drug monitoring have reduced the incidence of nephrotoxicity, ototoxicity remains unpredictable and may occur at ...
John H. McDermott, Sian Hilton, Cinzia Dello Russo, Nicola Booth, Simon Drysdale, Philip Howard, Stephen Hughes, Mallinath Chakraborty, Helen McDevitt, Charlotte Alston, Maya Desai, Mike Beadsworth, Adam Reynolds, Serim Min, Katherine Payne, Munir Pirmohamed, William G. Newman   +16 more
wiley   +1 more source

Dual Antibiotic-Infused Liposomes to Control Methicillin-Resistant Staphylococcus aureus

Medicines
Background: Methicillin-resistant Staphylococcus aureus (MRSA) considered under the category of serious threats by the Centers for Disease Control and Prevention (CDC), urges for new antibiotics or alternate strategies to control MRSA.
Sourav Chakraborty, Piyush Baindara, Surojit Das, Suresh K. Mondal, Pralay Sharma, Austin Jose T, Kumaravel V, Raja Manoharan, Santi M. Mandal   +8 more
doaj   +1 more source

Giant Fetal Sacrococcygeal Teratoma: Prenatal Detection, Monitoring, and Postnatal Management—A Case Report and Literature Review

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Sacrococcygeal teratoma (SCT) is a rare congenital tumor arising from pluripotent cells at the base of the coccyx and is most often detected during antenatal imaging. In this case, a massive SCT was identified at 26 + 2 weeks during routine ultrasound.
Tandin Om, Chimi Lhaky Zam, Karma Sherub, Phurb Dorji   +3 more
wiley   +1 more source

Recognition of Patau Syndrome (Trisomy 13) Based on Clinical Features in a Resource‐Limited Setting: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Patau syndrome (trisomy 13) is a life‐limiting chromosomal disorder with multiple congenital anomalies. We report a term male neonate with bilateral cleft lip and palate, aplasia cutis congenita, postaxial polydactyly, hypotonia, congenital heart disease, and presumed neonatal sepsis.
Sayed Hussain Amiri, Nasir Ahmad Anwari, Dawood Hossaini, Abdulhaq Qiam, Murtaza Haidary   +4 more
wiley   +1 more source

Amikacin-modified hybrid biomaterial biological properties

Current Issues in Pharmacy and Medical Sciences, 2010
Hydroxyapatite is used in bone reconstruction because of its similar chemical structure compared to the inorganic composition of human bone. Bone is a complex material composed of proteins, mainly collagen, with hydroxyapatite.
Justyna Zalewska, Grażyna Ginalska, Wojciech Brzana   +2 more
doaj  

In vitro studies of amikacin-loaded human carrier erythrocytes

, 2008
Erythrocyte-encapsulated antibiotics have the potential to provide an effective therapy against intracellular pathogens. The advantages over the administration of free antibiotics include a lower systemic dose, decreased toxicity, a sustained delivery of
Bax, BE, Lanao, JM, Castañeda, AZ, Marinero, ML, Gutiérrez Millán, C   +4 more
core   +1 more source

In Vitro and In Silico Analysis of Antioxidant and Antifungal Activity of Essential Oil From Achillea biebersteinii

ChemPlusChem, Volume 91, Issue 9, September 2026.
Essential oil of Achillea biebersteinii Afan. flowers exhibits moderate antioxidant activity in DPPH• and ABTS+ assays, while it demonstrates high anticandidal activity, with MFC (0.937−3.75 μL/mL) values. α‐Terpineol and trans‐Pinocarveol are antifungal compounds responsible for the effect against both C. glabrata and C.
Zehra Torun, Tuba Unver, M. Abdullah Alagoz   +2 more
wiley   +1 more source

Phytochemical Profiling and Antibacterial Activity of Moroccan Monofloral Honeys Against Multidrug‐Resistant Uropathogens: In Vitro, ADMET, Molecular Docking, and Molecular Dynamics Approaches

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Multidrug‐resistant bacteria infections require alternative antimicrobial strategies. This study evaluated the phenolic composition, antibacterial activity, and in silico properties of four Moroccan monofloral honeys. Carob honey showed the greatest phenolic diversity, whereas citrus honey contained the lowest polyphenolic content.
Mourad Chikhaoui, Aziz Galman, Ahmed Chetoui, Oussama Khibech, Mohamed Reda Kachmar, Toufik Bouddine, Mohamed Bouhrim, Fahd A. Nasr, Mohammed Al‐Zharani, Ashraf Ahmed Qurtam, Rachid Lotfi, Houda El Hajjouji   +11 more
wiley   +1 more source

In Vitro Antimicrobial Synergistic Activity and the Mechanism of the Combination of Naringenin and Amikacin Against Antibiotic-Resistant Escherichia coli

Microorganisms
Bacterial drug resistance is becoming an increasingly serious problem, and the development of antibacterial synergists is urgently needed. Combining existing antibiotics with promising nonantibiotic agents is one strategy that has been shown to be ...
Lankun Yi, Mingze Cao, Xu Chen, Yubin Bai, Weiwei Wang, Xiaojuan Wei, Yuxiang Shi, Yongying Zhang, Tenghe Ma, Zhen Zhu, Jiyu Zhang   +10 more
doaj   +1 more source

FIC values of Amikacin plus Levofloxacin combination.

, 2017
FIC values of Amikacin plus Levofloxacin combination.
Mona M. Abdelkader (3753058), Mohammad M. Aboulwafa (3753052), Marwa A. El-Ashry (3753055), Khaled M. Aboshanab (3753061)   +3 more
core   +1 more source