Results 91 to 100 of about 162,947 (233)

Resistance and efficiency of amikacin in critically ill septic children: a cross-sectional study

Journal of Pediatric and Neonatal Individualized Medicine
Background: Therapeutic drug monitoring facilitates the individualiza­tion of amikacin dosing for patients based on pharmacodynamics and pharmacokinetics.
Aya Osama Mohamed, HebatAllah Fadel Algebaly, Bola Fathallah Aziz, May Abdelfattah Mohamed, Amira Fathi Srour, Miriam Magdy Aziz, Mohamed Abdallah Abd El Megied   +6 more
doaj   +1 more source

Once-daily intramuscular amikacin for outpatient treatment of lower urinary tract infections caused by extended-spectrum β-lactamase-producing Escherichia coli in children

, 2017
Meltem Polat,1,2 Soner Sertan Kara1 1Pediatric Infectious Diseases Department, Erzurum Research and Training Hospital, Erzurum, 2Pediatric Infectious Diseases Department, Pamukkale University Faculty of Medicine, Denizli, Turkey Background: The rise in ...
Polat M, Kara SS
core  

Adjuvant Antibacterial Effects of Mouriri Elliptica Against Clinical Multidrug Resistant Gram‐Negative Bacterial Strains

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
The ethanolic leaf extract of Mouriri elliptica exhibited antibacterial and antibiofilm activities against multidrug‐resistant clinical isolates and enhanced the activity of ampicillin. Its diverse chemical profile and low acute toxicity support this Cerrado species as a promising source of natural antibacterial adjuvants. ABSTRACT Bacterial resistance
Talita Vilalva Freire, Ana Carolina de Freitas Marques, Valéria dos Santos Gonçalves, Iluska Senna Bonfá Moslaves, Mônica Cristina Toffoli‐Kadri, Arthur Feliciano Camargo da Silva, Martha Janete Giz, Patrícia de Oliveira Figueiredo, Ana Camila Micheletti, Nídia Cristiane Yoshida   +9 more
wiley   +1 more source

Genetic Diversity and Epidemiological Overlap of Staphylococcus aureus at the Animal–Food–Environment–Human Interface Within a One Health Framework

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Integrating farm‐to‐fork and clinical surveillance, this study reveals distinct SCCmec distributions alongside shared spa types across human, animal, and food interfaces. The results of genetic diversity and epidemiological overlap underscore the critical need for coordinated One Health surveillance to monitor multi‐sectoral Staphylococcus aureus ...
Pinar Sagiroglu, Dursun Alp Gundog, Candan Gungor, Kursat Koskeroglu, Mustafa Altay Atalay, Adalet Dishan, Yeliz Ucar, Aytac Akcay, Huseyin Burak Disli, Harun Hizlisoy, Mukaddes Barel, Tekin Kececi, Nurhan Ertas Onmaz   +12 more
wiley   +1 more source

Population Pharmacokinetic Modelling of Amikacin in Neonates [PDF]

, 2011
Objectives: The aim of this study was to explore the influence of demographic and clinical covariates, and hence to develop population pharmacokinetic (PK) model of amikacin in neonates with suspected or proven sepsis.
Vučićević, Katarina, Prostran, Milica, Slavković, Bojana, Miljković, Branislava, Rakonjac, Zorica, Kovačević, Milena   +5 more
core   +2 more sources

Population pharmacokinetics of amikacin in Algeria: implications for dosing optimization and individualized therapy.

Batna Journal of Medical Sciences
Introduction: Amikacin is a bactericidal aminoglycoside widely used in the treatment of severe infections caused by multidrug-resistant Gram-negative bacilli.
Fatima Zohra BOUAOUA, Houari TOUMI, Karim BOULESBIAAT, Habiba FETATI, Hocine GACEM, Farida BOUCHNAK, Abdelrahmane ABDAOUI, Zahia HAZMOUNE, Badis FOUGHALI, Soumia BOUDJEMAA, Sabah BENBOUDIAF, Fatma Zohra BOUDIA, Rafika LAICHE, Faiza BOUCHALA, Kamel MANSOURI   +14 more
doaj   +1 more source

Amikacin-resistant atypical mycobacterial keratitis

Here, we report a novel case of amikacin-resistant atypical mycobacterial keratitis in a man in his third decade. He presented with gradual diminution of vision associated with pain, redness, watering in his left eye of 1½ months' duration, with a ...
Nisha Vilas Rahul, Himansu Sekhar Behera, Smruti Rekha Priyadarshini   +2 more
core   +1 more source

Comparative Genomic Analysis of Multidrug‐Resistant Escherichia coli Across Poultry–Human–Environmental Interfaces

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Whole‐genome sequencing analysis of Escherichia coli isolates from broiler, layer and sonali chickens in Bangladesh shown extensive antimicrobial resistance, diverse virulence factors, plasmid‐mediated resistance, and a highly open pangenome. Comparative genomic analyses demonstrated close genetic relationships with global strains, highlighting the One
Md. Rokibul Hasan Shanto, A. S. M. Ashab Uddin, Md. Shakil Mahmud Supto, Nabil Jahan Mahim, Md. Matiar Rahman Howlader, Syed Sayeem Uddin Ahmed, Md Bashir Uddin   +6 more
wiley   +1 more source

Nasopharyngeal Carriage Rate, Risk Factors, and Co‐Resistance Patterns of Methicillin‐Resistant Staphylococcus aureus in Ethiopia: Systematic Review and Meta‐Analysis

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
This systematic review and meta‐analysis show that nasopharyngeal carriage of methicillin‐resistant Staphylococcus aureus remains an important public health concern in Ethiopia. High resistance to commonly used antibiotics and significant associations with prior hospitalization and antibiotic use highlight the need for strengthened antimicrobial ...
Simachew Getaneh Endalamew, Sofiya Ayalew Kebede, Solomon Keflie Assefa, Adem Tsegaw Zegeye, Belayneh Jejaw Abate, Dejen kahsay Asgedom, Eliyas Addisu Taye, Endalew Minwuye Andargie, Eyob Akalewold Alemu, Halima Ayalew Kebede, Alebachew Tilahun Wassie, Andnet Yirga Assefa, Yihenew Getahun Ambaw, Helen Brhan Alemaw   +13 more
wiley   +1 more source

Proteomic Analysis of Three Independent Series of Sequential Cystic Fibrosis Strains in an International Pseudomonas aeruginosa Reference Panel Indicates Positive Selection in Late Infection Strains

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Comparison of proteomes from three series of sequential Pseudomonas aeruginosa isolates from people with cystic fibrosis identified eleven proteins with increased abundance in at least one late isolate per patient. Three proteins were increased in all five late isolates, and the probability of this occurring by chance is 5.06 × 10−53, indicating strong
Joanna Drabinska, Lucia O'Connor, Caoilin McClean, Siobhán McClean   +3 more
wiley   +1 more source