Results 91 to 100 of about 145,366 (199)

Polyglutamic Acid‐Based Injectable Hydrogel: Design, Fabrication, and Evaluation in Accelerating Infected Wound Repair

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This study developed an injectable hydrogel (PGBP) based on polyglutamic acid. When loaded with amikacin (Ami@PGBP), the hydrogel system exhibits sustained drug release and potent antibacterial activity. It also reduces inflammation, effectively accelerating the closure and regeneration of infected wounds in vivo while demonstrating good biosafety ...
Yipeng Sun, Saifei Lv, Chenxu Lv, Tong Ren, Yuxin Wang, Yiqiu Xiong, Yanan Lu, Rongpeng Li, Yongli Shi, Xueyan Hou   +9 more
wiley   +1 more source

Safety Evaluation of Weissella paramesenteroides MW‐142 Isolated From Traditional Fermented Mulberry Wine

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Integrated safety evaluation of Weissella paramesenteroides MW‐142 from traditional fermented mulberry wine demonstrates no acute oral toxicity, non‐hemolytic activity, absence of harmful metabolites, and only intrinsic, non‐mobile antibiotic resistance genes, supporting its potential as a safe candidate for probiotic or biopreservative applications ...
Juan Huang, Yan‐yan Huang, Dong‐mei Liu, Qing‐bo Yao, Jun Tang, Su‐ping Zeng, Liu‐jun Liu   +6 more
wiley   +1 more source

When First‐Line Therapies Fail: Surgical Site Infections and the Declining Antimicrobial Utility in a Resource‐Limited Nation

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
In Belize, a 7‐year nationwide study reveals a sharp rise in antimicrobial resistance in surgical infections. ESBL‐producing bacteria more than doubled to > 45%, with critical treatment gaps and geographic hotspots identified. Sentinel pan‐drug‐resistant cases and a correlation between antibiotic use and resistance underscore the urgent need for ...
Innocent E. Nwachukwu, Cary W. Rivera, Vivian M. Reyes, Diomar Salazar, Lydia Harris‐Thurton, Danladi C. Husaini   +5 more
wiley   +1 more source

Hospital‐Associated Antimicrobial Resistant Bacteria on 95 Mobile Phones: An International Metagenomic “Phonome” Analysis

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
On average, phones harbored 3.62 of the top 10 killers and 2.49 ESKAPE organisms. In total, 667 VFGs (8621 Hits) and 262 ARGs (2475 Hits) were identified on 95 mobile phones. Mobile phones serve as a platform for horizontal gene transfer and AMR development.
Adrian Goldsworthy, Matthew Olsen, Nchafatso G. Obonyo, Peter Jones, Simon McKirdy, Abiola Senok, Rashed Alghafri, Rose Ghemrawi, Reem Almheiri, Oystein Tronstad, Jacky Y. Suen, John F. Fraser, Lotti Tajouri   +12 more
wiley   +1 more source

Antibiotic Resistance and Biofilm Gene Distribution in Colistin‐Resistant Acinetobacter baumannii

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Multicenter analysis of 144 clinical Acinetobacter baumannii isolates in Iran revealed high MDR/XDR rates and widespread biofilm formation (90.9%). Colistin resistance was linked to pmrAB overexpression, while blaPER‐1 was independently associated with strong biofilm production, highlighting chromosomal resistance mechanisms and biofilm as key drivers ...
Zainab Amer Hatem, Fadhela Nafaa Kafe, Farkad Hawas Musa, Sarah F. Al‐Taie, Nabaa Hisham Ateya, Leqaa Majeed Aziz, Erta Rajabi, Raad N. Hasan   +7 more
wiley   +1 more source

Interplay Between Virulence Genes, Antimicrobial Resistance Profiles, and Biofilm Formation in Klebsiella pneumoniae Causing Urinary Tract Infections in North Lebanon

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
– Figure design (single panel) Central icon: K. pneumoniae cell Left panel – Virulence genes (icons): Adhesion: fimH, mrkD → strong biofilm Capsule/regulation: magA, rmpA Siderophores: entB, iucA → iron uptake Right panel – Outcomes: Biofilm strength (weak → strong gradient) Antibiotic resistance (ESBL, MDR) Bottom split: Hospital‐acquired → strong ...
Mazen Zaylaa, Rayan Farha, Jana Taleb, Amal Saad, Omar El Gharbawy, Ricardo Sarraf, Ibtihal Kassam, Chadi Hamdach, Nisrine Bissar   +8 more
wiley   +1 more source

Prevalence, Antimicrobial Resistance, and Resistance Gene Profiles of Extended‐Spectrum β‐Lactamase‐Producing Escherichia coli and Klebsiella pneumoniae Isolated From Quails in Sylhet, Bangladesh

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
This study investigated the molecular epidemiology and antimicrobial resistance of Escherichia coli and Klebsiella pneumoniae isolated from quails in Bangladesh. High prevalence of E. coli, including Shiga toxin‐producing strains, and widespread multidrug resistance were observed.
Md. Al Mamun, Hemayet Hossain, Md. Shahidur Rahman Chowdhury, Shahida Begum Nargis, Munni Rani Das, Rakibul Hasan, Nasrin Akter Liza, Shuvojit Mitra, Md Bashir Uddin, Md. Mukter Hossain, Md. Mahfujur Rahman   +10 more
wiley   +1 more source

Smart Polymer‐Based Drug Delivery Systems for Managing Infective Conjunctivitis: Advances and Future Prospects

Nano Select, Volume 7, Issue 6, June 2026.
The introduction covers the background and significance of conjunctivitis. It continues with a review of etiology, epidemiology, and clinical manifestations. Diagnostic methods are described, followed by discussions on pathophysiology and classification. Current treatment strategies, preventive measures, and therapeutic challenges are analyzed.
Xia Linkang, Marwan Abdelmahmoud Abdelkarim Maki, Saad Tayyab, Sachin Thakur, Pankaj Kumar, Ritu Karwasra, Mahesh Harihar Behare, Nitin Sharma, Wan Hamirul Bahrin Wan Kamal, Oganeswary Kobi, Kushagra Khanna, Mogana Rajagopal   +11 more
wiley   +1 more source

Efeito da oxigenação hiperbárica em lesão ototóxica produzida pela amicacina em cobaias The effects of hyperbaric oxygen therapy upon ototoxic injuries produced by amikacin in guinea pigs

Brazilian Journal of Otorhinolaryngology, 2013
A oxigenação hiperbárica têm favorecido a prevenção e o tratamento de afecções auditivas como a ototoxicidade. OBJETIVO: Estudar os efeitos da oxigenação hiperbárica em lesão ototóxica promovida pela amicacina. Forma de estudo: Experimental.
Luciana de Albuquerque Salviano Amora, Adriana de Andrade Batista Murashima, Maria Rossato, Márcia Bento Moreira, Miguel Ângelo Hyppolito, Djalma José Fagundes   +5 more
doaj  

The Role of Pharmacovigilance Database in Identifying Antibiotic Resistance and Inappropriate Use: An Analysis of VigiBase Reports From Lower‐Middle‐Income Countries

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Background Digital databases such as pharmacovigilance (PV) databases could provide unique opportunities to monitor trends in suspected antibiotic resistance, ineffectiveness, and misuse, extending beyond their traditional role of tracking adverse drug reactions (ADRs).
Hager Saleh, Joseph Mitchell, Cecilia Stålsby Lundborg, Megha Sharma   +3 more
wiley   +1 more source