Results 71 to 80 of about 205,880 (261)

Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens. [PDF]

, 2019
The burden of meningitis in low-and-middle-income countries remains significant, but the infectious causes remain largely unknown, impeding institution of evidence-based treatment and prevention decisions.
Crawford, Emily D., de Bourcy, Charles, De Carvalho, Tiago Rodrigues, DeRisi, Joseph L., Dimitrov, Boris, Duggal, Nisha, Egger, Rebecca, Hasanuzzaman, Md, Islam, Maksuda, Juan, Yun-Fang, Kalantar, Katrina, Khan, Lillian M., Langelier, Charles, Li, Lucy M., Malaker, Roly, Mayday, Madeline Y., Rahman, Hafizur, Ramesh, Akshaya, Saha, Samir K., Saha, Senjuti, Sajib, M. S. I., Sheu, Jonathan, Tang, Jennifer, Tato, Cristina M., Wang, James, Wilson, Michael R.   +25 more
core   +2 more sources

Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae

Interdisciplinary Medicine, EarlyView.
A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang, Zhuolin Li, Yang Yang, Zihan He, Tyuji Hoshino, Vladislav Victorovich Khrustalev, Qing Zhu, Weiling Wu, Wei Zhao, Chenguang Shen, Shi Ouyang   +10 more
wiley   +1 more source

Aetiology, Antimicrobial Susceptibility and Predictors of\ud Urinary Tract Infection among Febrile Under-Fives at\ud Muhimbili National Hospital, Dar es Salaam-Tanzania [PDF]

, 2013
Urinary tract infection (UTI) is a common cause of fever in children and contributes to morbidity and mortality. This study aimed at determining prevalence, aetiology and antimicrobial susceptibility pattern of the isolates at Muhimbili National Hospital
Fataki, Maulidi, Francis, Joel M., Fredrick, Francis, Maselle, Samuel Y.   +3 more
core  

Mycobacterial panniculitis caused by Mycobacterium thermoresistibile in a cat. [PDF]

, 2016
Case summaryA domestic shorthair cat was evaluated for chronic, bilateral, ulcerative dermatitis affecting the inguinal region and lateral aspects of both pelvic limbs.
Keel, M Kevin, Reagan, Krystle L, Sykes, Jane E, Vishkautsan, Polina   +3 more
core   +2 more sources

Genomic Insights Into Carbapenem‐Resistant Klebsiella pneumoniae in Pediatric Bloodstream Infections in Zhejiang, China (2019–2024)

Journal of Clinical Laboratory Analysis, EarlyView.
The primary mechanism of carbapenem resistance identified in pediatric CRKP‐BSI strains was the production of Class B metalloenzymes. We report, for the first time, an outbreak of bloodstream infections in a neonatal ward caused by the dissemination of NDM‐1‐producing ST25 K. pneumoniae.
Mingming Zhou, Xiucai Zhang, Zhenjie Chen, Chao Fang, Shixing Liu, Jintao Xia, Yining Zhao, Chenmei Zhang, Hongqiang Shen   +8 more
wiley   +1 more source

Clinical microbiology study of diabetic foot ulcer in Iran; pathogens and antibacterial susceptibility [PDF]

, 2012
The aim of this study was to investigate microbial pathogens and their antibiotic susceptibility profile in infected diabetic foot ulcers in Iranian patients.
Hayatshahi, A., Heshmat, R., Nikoo, M.K., Qorbani, M., Rouhipour, N., Yazdi, N.M.   +5 more
core   +1 more source

Comparative analysis of the pathogenicity between multidrug-resistant Acinetobacter baumannii clinical isolates: isolation of highly pathogenic multidrug-resistant A. baumannii and experimental therapeutics with fourth-generation cephalosporin cefozopran

Infection and Drug Resistance, 2018
Satoshi Nishida, Yasuo Ono Department of Microbiology and Immunology, Teikyo University School of Medicine, Itabashi, Tokyo, Japan Introduction: The pathogenicity of fatal-outbreak Acinetobacter baumannii isolates has not been fully investigated.
Nishida S, Ono Y
doaj  

Renal Impact of a High-Loading Dose of Amikacin in Critically Ill Patients [PDF]

Pharmaceutical Sciences
Background: Aminoglycosides are potent bactericidal antibiotics primarily employed for gram-negative infections. However, they face limitations due to potential renal toxicity when administered at high doses. This study aimed to assess the nephrotoxicity
Laleh Mahmoudi, Arezoo Ahmadi, Motahareh Mahi-Birjand, Effat Alemzadeh, Parvin Askari, Ramin Niknam, Mojtaba Mojtahedzadeh   +6 more
doaj   +1 more source

Aminoglycoside trough levels in neonates [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2010
Introduction. Drug safety depends on trough levels. Objective. Objective of the study was to measure gentamicin and amikacin trough levels in neonates and to identify risk groups by gestational and postnatal age. Methods.
Pejović Biljana, Ranković-Janevski Milica, Božinović-Prekajski Niveska   +2 more
doaj   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source