Results 71 to 80 of about 145,366 (199)

Use of a 3D‐printed custom‐designed tracheostomy tube to stabilise a permanent tracheostoma in a 25‐year‐old Icelandic mare

Equine Veterinary Education, Volume 38, Issue 7, Page e399-e405, July 2026.
Summary A 25‐year‐old Icelandic mare diagnosed with bilateral temporohyoid‐osteoarthropathy, moderate pharyngeal instability and bilateral laryngeal paralysis was presented because of intermittent stridor and dyspnoea worsening during exercise. As a previous ceratohyoidectomy had not improved these symptoms substantially, a permanent tracheostomy was ...
D. C. Debald, J. P. Schramel, E. Haltmayer, N. M. Biermann   +3 more
wiley   +1 more source

Optimal Amikacin Levels for Patients with Sepsis in Intensive Care Unit of Cipto Mangunkusumo Hospital, Jakarta, Indonesia

Acta Medica Indonesiana, 2017
Background: Amikacin is one of the antibiotics of choice for sepsis and septic shock. Pharmacokinetic of amikacin can be influenced by septic condition with subsequent effect on its pharmacodynamic.
Gestina Aliska, Rianto Setiabudi, purwantyastuti purwantyastuti, Anis Karuniawati, Rudyanto Sedono, Trisni U Dewi, Muhammad K Azwar   +6 more
doaj  

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

Carvacrol attenuates amikacin-induced nephrotoxicity in the rats

Recent Trends in Pharmacology
Objective: Amikacin (AK) is a wide-spectrum antibiotic routinely used to treat gram-negative and some gram-positive bacterial infections. However, its use is limited due to its potential to cause nephrotoxicity due to an increase in reactive oxygen ...
Cemil Çolak, Ahmet Sefa Duman, Yılmaz Çiğremiş, Atta Mohammad Dost, Selahattin Tunç, Nigar Vardı, Azibe Yıldız, Onural Özhan, Hakan Parlakpınar, Mehmet Günata   +9 more
doaj   +1 more source

Consistency and clarity of pharmacogenomic guidance in UK medicine patient information leaflets: A cross‐sectional analysis

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1934-1939, June 2026.
Pharmacogenomic (PGx) information has the potential to support the safe and effective use of medicines, yet there is uncertainty about how this information can be best communicated to patients. Summaries of product characteristics (SmPCs) and patient information leaflets (PILs) for all UK‐approved medicines with strong evidence supporting a PGx ...
Parth Narlawar, Chloe Ratcliffe, Videha Sharma, William G. Newman, Munir Pirmohamed, John McDermott   +5 more
wiley   +1 more source

Determining the Protective Effect of L-Arginine Against Amikacin-Induced Nephrotoxicity in Normal African Green Monkey Kidney Epithelial Cells by Evaluating Oxidative Stress Parameters [PDF]

مجله دانشگاه علوم پزشکی گرگان
Background and Objective: Due to high metabolic activity and rich blood supply, the kidneys are exposed to high levels of reactive oxygen species (ROS) under pathological conditions, making them highly vulnerable to oxidative stress.
Elahe Gharehkhani, Marzieh Megharad, Mahboube Rahmati Kukandeh, Mohammad Shokrzadeh   +3 more
doaj  

Antibiotic Sensitivity Testing and Molecular Characteristics Related to Clarithromycin and Amikacin Resistance in Mycobacterium abscessus Complex Isolated from Patients with Pulmonary Infection at National Hospital 74, Vietnam

International Journal of Mycobacteriology
Background: Mycobacterium abscessus complex (MABC) is an important cause of opportunistic infections in the respiratory tracts. Data on antimicrobial resistance of MABC in Vietnam were still lacking. Methods: From December 2021 to July 2022, mycobacteria
Vu Thi Thuong, Bui Thi Thanh Nga, Le Thi Lan Anh, Nguyen Van Doai, Nguyen Minh Phuong, Luu Van Doan, Pham Viet Hung   +6 more
doaj   +1 more source

Ultrasound‐Guided Nerve Hydrodissection for Sural Nerve Injury: A Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Sural nerve entrapment is a relatively uncommon cause of lateral ankle and foot pain and sensory disturbance. Conventional management generally lacks direct, targeted intervention at the site of nerve injury. We report a case of a 33‐year‐old male patient who developed sural neuropathy secondary to a right ankle sprain. Diagnosis was confirmed
Mengshan Zhu, Qiang Duan, Liangwen Sun, Fengli Yu, Chunxia Wei, Yumin Wang, Junjie Jian, Bo Wang, Xiaoqun Huang   +8 more
wiley   +1 more source

Incidence of Acute Kidney Injury in Autologous Hematopoietic Stem Cell Transplant Recipients According to the Administration of Empirical Amikacin: A Two-Centre Retrospective Cohort Study

Antibiotics
Background: The benefit of adjunctive aminoglycosides in the treatment of patients with febrile neutropenia (FN) is controversial. We investigated the incidence of acute kidney injury (AKI) in patients with FN or suspected infection according to ...
Sophie Schürch, Sarah Dräger, Michèle Hoffmann, Severin Bausch, Nicolas Gürtler, Cédric Hirzel, Jakob Passweg, Stefano Bassetti, Thomas Pabst, Parham Sendi, Michael Osthoff   +10 more
doaj   +1 more source