Results 61 to 70 of about 205,880 (261)

Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]

, 2018
Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung, Fong-Chuen Loo, Jacky, Ip, Margaret, Lau, Terrence Chi-Kong, Lin, Xiao, Qin, Hao, Tsui, Stephen Kwok-Wing, Wai-Sing Lo, Norman, Yim, Aldrin Kay-Yuen   +8 more
core   +2 more sources

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Bacterial pathogens and resistance causing community acquired paediatric bloodstream infections in low- and middle-income countries: a systematic review and meta-analysis [PDF]

, 2019
Background Despite a high mortality rate in childhood, there is limited evidence on the causes and outcomes of paediatric bloodstream infections from low- and middle-income countries (LMICs).
Basmaci, R, Dramowski, A, Droz, N, Ellis, S, Hsia, Y, Sharland, M   +5 more
core   +2 more sources

GenoType NTM-DR Performance Evaluation for Identification of Mycobacterium avium Complex and Mycobacterium abscessus and Determination of Clarithromycin and Amikacin Resistance

Journal of Clinical Microbiology, 2019
We evaluated the GenoType NTM-DR (NTM-DR) line probe assay for identifying Mycobacterium avium complex (MAC) species and Mycobacterium abscessus subspecies and for determining clarithromycin and amikacin resistance. Thirty-eight reference strains and 145
H. Huh, Su-Young Kim, Hyang Jin Shim, Dae Hun Kim, I. Yoo, O. Kang, C. Ki, So Youn Shin, B. W. Jhun, S. Shin, C. Daley, W. Koh, N. Lee   +12 more
semanticscholar   +1 more source

From Food Waste to Valorized Nanomaterials: Sustainable Green Synthesis and Biomedical Applications

ChemFoodChem, EarlyView.
Food waste‐derived biomolecules act as natural reducing and stabilizing agents for the green synthesis of functional NPs with applications in antimicrobial systems, food packaging, biomedical technologies, and environmental remediation. ABSTRACT Food waste is a global issue, with billions of tons discarded and unutilized annually, causing economic ...
Siddhraj Rajput, Gautam Priyadarshi, Santosh Kumar Sahu, Bhakti Patel, Avni Thakker, Sherzodbek Tashbaev, Gulomov Gafurjon Shavkatbek Ugli, Dipak Kumar Sahoo, Ashish Patel   +8 more
wiley   +1 more source

Drug Critical Limits for Urgent Physician Notification

Clinical Pharmacology &Therapeutics, EarlyView.
Critical limits represent quantitative decision thresholds for drugs that require immediate clinician notification and potential life‐saving intervention. United States hospitals lack a national standard for drug critical limits. We collected critical limits from 417 US hospitals across all 50 states and Washington, D.C.; of these, 411 maintained drug ...
Elina Kuang, Yasmeen Ibrahim, Kyle Cheng, Gerald J. Kost   +3 more
wiley   +1 more source

In Vitro Characterization of Technological and Health‐Promoting Properties of Enterocin Producing Lactic Acid Bacteria From Camel Milk and Its Suitability as a Dairy Starter

Food Chemistry International, EarlyView.
Enterocin‐producing Enterococcus faecium RSCUDR7 from camel milk exhibited strong probiotic and antimicrobial properties, along with stability in skim milk. Its suitability as a safe and effective dairy starter highlights its potential for developing functional probiotic dairy products.
Rahul Singhal, Kamalesh Kumar Meena, Manvik Joshi, Lokesh Gupta, Sunil Meena   +4 more
wiley   +1 more source

Dynamics and quantitative contribution of the aminoglycoside 6′-N-acetyltransferase type Ib to amikacin resistance

mSphere
Aminoglycosides are essential components in the available armamentarium to treat bacterial infections. The surge and rapid dissemination of resistance genes strongly reduce their efficiency, compromising public health.
Ophélie d’Udekem d’Acoz, Fong Hue, Tianyi Ye, Louise Wang, Maxime Leroux, Lucila Rajngewerc, Tung Tran, Kimberly Phan, Maria S. Ramirez, Walter Reisner, Marcelo E. Tolmasky, Rodrigo Reyes-Lamothe   +11 more
doaj   +1 more source

Nitrofurantoin Combined With Amikacin: A Promising Alternative Strategy for Combating MDR Uropathogenic Escherichia coli

Frontiers in Cellular and Infection Microbiology, 2020
Urinary tract infections (UTI) are common infections that can be mild to life threatening. However, increased bacterial resistance and poor patient compliance rates have limited the effectiveness of conventional antibiotic therapies.
Zi-Xing Zhong, Zi-Xing Zhong, Ze-Hua Cui, Ze-Hua Cui, Xiao-Jie Li, Tian Tang, Tian Tang, Zi-Jian Zheng, Zi-Jian Zheng, Wei-Na Ni, Wei-Na Ni, Liang-Xing Fang, Liang-Xing Fang, Yu-Feng Zhou, Yu-Feng Zhou, Yang Yu, Yang Yu, Ya-Hong Liu, Ya-Hong Liu, Ya-Hong Liu, Xiao-Ping Liao, Xiao-Ping Liao, Xiao-Ping Liao, Jian Sun, Jian Sun, Jian Sun   +25 more
doaj   +1 more source

Evaluation of Intra-Articular Amikacin Administration in an Equine Non-inflammatory Joint Model to Identify Effective Bactericidal Concentrations While Minimizing Cytotoxicity

Frontiers in Veterinary Science, 2021
Septic arthritis causes significant morbidity and mortality in veterinary and human clinical practice and is increasingly complicated by multidrug-resistant infections.
Lynn Pezzanite, Lyndah Chow, Dean Hendrickson, Daniel L. Gustafson, A Russell Moore, Jason Stoneback, Gregg M. Griffenhagen, Gabriella Piquini, Jennifer Phillips, Paul Lunghofer, Steven Dow, Steven Dow, Laurie R. Goodrich   +12 more
doaj   +1 more source