Results 51 to 60 of about 146,046 (188)
Transgenic selection and underlying mechanisms in apicomplexan parasites
The FEBS Journal, EarlyView.Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju +2 more
wiley +1 more source
Journal of Education, Health and Sport, 2017 The mice were divided into 9 groups for the experimental part. We have been studying clinical parameters of haemogram: the number of red blood cells, the value of ESR, hemoglobin, leukocyte formula.
O. Y. Kosilova +2 more
doaj
Frontiers in PharmacologyBackgroundAcute kidney injury (AKI) is a significant concern among hospitalized patients receiving aminoglycosides. Identifying the risk factors associated with aminoglycoside-induced AKI and developing machine learning models are imperative in clinical ...
Pei Zhang +6 more
doaj +1 more source
Internal Medicine Journal, EarlyView.Abstract Background Pharmacogenomic‐guided medication management optimises drug therapy to enhance patient outcomes. Despite clinical utility, implementation in Australia remains limited, partly due to the lack of clear and consistent guidance. Aim This study evaluated the presence and consistency of pharmacogenomic testing indication categories and ...
Ruby Soueid +4 more
wiley +1 more source
Microbiology SpectrumMycobacterium abscessus pulmonary disease is increasing in prevalence globally, particularly for individuals with cystic fibrosis. These infections are challenging to treat due to a high rate of resistance.
Joy E. Gibson +2 more
doaj +1 more source
Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers
Journal of Periodontal Research, EarlyView.Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed +1 more
wiley +1 more source
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT Veterinary students often find it difficult to select antimicrobial drugs for patients, likely because it requires them to consider multiple factors and there are frequently several possible options with a lack of a defined “correct or incorrect” choice. Our goal was to develop a teaching tool to engage the students through the decision‐making
Carly A. Patterson +2 more
wiley +1 more source
Polymer Complexes of Amikacin with Sulfur-Containing Polymers
Антибиотики и ХимиотерапияPolymer complexes of amikacin based on two sulfonic polymers, dextran sulfonic acid and poly-2-acrylamido-2-methylpropane sulfonic acid, containing 25 and 33 wt % of the antibiotic, respectively, have been synthesized.
A. Yu. Semina +2 more
doaj +1 more source
Molecular Microbiology, EarlyView.AGXX enhances aminoglycoside activity against multidrug‐resistant pathogens such as uropathogenic Escherichia coli by increasing reactive oxygen species, causing protein aggregation and DNA damage. This effect is reduced by oxygen limitation or antioxidants. Polyphosphate protects cells from oxidative damage.
Emmanuel P. Oladokun +9 more
wiley +1 more source
陆军军医大学学报Objective To investigate the effects of meropenem and amikacin on gut microbiota diversity and composition in a neonatal rat model of necrotizing enterocolitis (NEC).
ZHANG Chenghuan +2 more
doaj +1 more source