Results 31 to 40 of about 146,046 (188)

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

iLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

Heteroresistance to Amikacin in Carbapenem-Resistant Klebsiella pneumoniae Strains

Frontiers in Microbiology, 2021
Heteroresistance can lead to treatment failure and is difficult to detect by the methods currently employed by clinical laboratories. The aim of this study was to investigate the prevalence of the amikacin-heteroresistant Klebsiella pneumoniae strains ...
Feiyang Zhang, Qin Li, Jiawei Bai, Manlin Ding, Xiangjin Yan, Guangxi Wang, Baoli Zhu, Yingshun Zhou   +7 more
doaj   +1 more source

Effects of post‐hepatic portoenterostomy adjuvant therapy on liver transplantation in children with biliary atresia: A systematic review

JPGN Reports, EarlyView.
Abstract Objectives Biliary atresia (BA) is a cholangiopathy characterized by obstruction of the intrahepatic and extrahepatic bile ducts. Hepatic portoenterostomy (HPE) is the primary palliative treatment and there is still an urgent need to improve post‐HPE management.
Bianca Ferraz de Almeida Silva, Alice Palmeira Nascimento Cerqueira, Breno Oliveira Marques, Gabriela Garcia de Carvalho Laguna, Gabrielle dos Santos Aguiar, Luana Leal Gonzaga, Raquel Teles de Lacerda, Natalia Oliveira e Silva   +7 more
wiley   +1 more source

Detecting Antibiotic Resistance in Strains of Selected Gram‐Negative Bacterial Species Using Raman Spectroscopy

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy successfully identified antibiotic‐resistant Gram‐negative strains. Resistant strains of four bacterial species were discriminated from sensitive ones with 99.1% accuracy using PLS regression. The method allows for rapid, label‐free detection of antibiotic resistance.
Fernanda Sant Ana de Siqueira e Oliveira, Adriano Moraes da Silva, Marcos Tadeu T. Pacheco, Landulfo Silveira Jr.   +3 more
wiley   +1 more source

Dynamics and quantitative contribution of the aminoglycoside 6′-N-acetyltransferase type Ib to amikacin resistance

mSphere
Aminoglycosides are essential components in the available armamentarium to treat bacterial infections. The surge and rapid dissemination of resistance genes strongly reduce their efficiency, compromising public health.
Ophélie d’Udekem d’Acoz, Fong Hue, Tianyi Ye, Louise Wang, Maxime Leroux, Lucila Rajngewerc, Tung Tran, Kimberly Phan, Maria S. Ramirez, Walter Reisner, Marcelo E. Tolmasky, Rodrigo Reyes-Lamothe   +11 more
doaj   +1 more source

Amikacin and renal Impairment: optimized dosing regimens by pharmacokinetic simulation according to KDIGO Stages. [PDF]

Batna Journal of Medical Sciences
Introduction: Pharmacokinetic simulations enable evaluation of the impact of dosing regimens and administration intervals on the achievement of therapeutic targets for amikacin, particularly in patients with renal impairment.
Fatima Zohra BOUAOUA, Karim BOULESBIAAT, Houari TOUMI, Pierre MARQUET, Sihem ZITOUNI, Sabah BENBOUDIAF, Soumia BOUDJEMAA, moufida GHARBI, Hocine GACEM, Haroune BOUAB, Nouar BOUDJOUREF, Nadia BOULEKHAL, Zoulikha BENHACINE, Zahra OUCHNENE, Zahia HAZMOUNE, Khaled BOUZENDA, Zakaria BOUREZAK, Abd El Jalil LALAOUNA, Mehdi GUEROUI, Nacer KHARNANE, Chaouki DERDOUS, Zahia BENABID, Linda AIMEUR, LAMARA Malika   +23 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

ISOLATION AND CHARACTERIZATION OF CITROBACTER FREUNDII FROM FRESH WATER COMMON CARP (CYPRINUS CARPIO) IN MOSUL CITY [PDF]

Assiut Veterinary Medical Journal
Citrobacter freundii is an opportunistic pathogen in animals and humans. The current study aimed to isolate C. freundii from the intestines of common carp (Cyprinus carpio) and test their antibiotic susceptibility.
MOHAMMAD HAMAD, SUMAYA ALDABBAGH, ISRAA KHALIL   +2 more
doaj   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

Nitrofurantoin Combined With Amikacin: A Promising Alternative Strategy for Combating MDR Uropathogenic Escherichia coli

Frontiers in Cellular and Infection Microbiology, 2020
Urinary tract infections (UTI) are common infections that can be mild to life threatening. However, increased bacterial resistance and poor patient compliance rates have limited the effectiveness of conventional antibiotic therapies.
Zi-Xing Zhong, Zi-Xing Zhong, Ze-Hua Cui, Ze-Hua Cui, Xiao-Jie Li, Tian Tang, Tian Tang, Zi-Jian Zheng, Zi-Jian Zheng, Wei-Na Ni, Wei-Na Ni, Liang-Xing Fang, Liang-Xing Fang, Yu-Feng Zhou, Yu-Feng Zhou, Yang Yu, Yang Yu, Ya-Hong Liu, Ya-Hong Liu, Ya-Hong Liu, Xiao-Ping Liao, Xiao-Ping Liao, Xiao-Ping Liao, Jian Sun, Jian Sun, Jian Sun   +25 more
doaj   +1 more source