Results 11 to 20 of about 205,880 (261)

Amikacin-loaded niosome nanoparticles improve amikacin activity against antibiotic-resistant Klebsiella pneumoniae strains

open access: yesWorld Journal of Microbiology & Biotechnology, 2022
Amikacin is an aminoglycoside antibiotic used in drug-resistant bacterial infections. The spread of bacterial infections has become a severe concern for the treatment system because of the simultaneous drug resistance bacteria and SARS-CoV-2 hospitalized
M. Rahmati   +2 more
semanticscholar   +1 more source

Effect of Imipenem and Amikacin Combination against Multi-Drug Resistant Pseudomonas aeruginosa

open access: yesAntibiotics, 2021
Pseudomonas aeruginosa is an opportunistic nosocomial pathogen associated with high morbidity and mortality rates. Combination of antibiotics has been found to combat multi-drug resistant or extensively drug resistance P. aeruginosa.
Sara Mahmoud Farhan   +6 more
doaj   +1 more source

Robustness of Aerosol Delivery of Amikacin Liposome Inhalation Suspension using the eFlow® Technology.

open access: yesEuropean journal of pharmaceutics and biopharmaceutics, 2021
The purpose of these studies was to understand the effect on product performance of batch-to-batch variability in both the amikacin liposome inhalation suspension (ALIS) formulation and its delivery device, the Lamira® nebulizer system, designed and ...
Zhili Li, W. Perkins, D. Cipolla
semanticscholar   +1 more source

Review on Population Pharmacokinetics of Amikacin in Paediatrics

open access: yesJournal of Pure and Applied Microbiology, 2022
Amikacin is an aminoglycoside antibiotic with a broad-spectrum bacterial coverage that is frequently utilized both as monotherapy and in combination with other antibiotics for severe bacterial infections in the paediatric population.
Keerthana Chandrasekar   +4 more
doaj   +1 more source

Susceptibility of bacterial endophthalmitis isolates to vancomycin, ceftazidime, and amikacin

open access: yesScientific Reports, 2021
Bacterial endophthalmitis is a rare intraocular infection, and prompt administration of intravitreal antibiotics is crucial for preventing severe vision loss.
Kuan-Jen Chen   +10 more
semanticscholar   +1 more source

The role of amikacin in the treatment of nontuberculous mycobacterial disease

open access: yesExpert Opinion on Pharmacotherapy, 2021
Introduction: Guidelines recommend the use of amikacin in the treatment of nontuberculous mycobacterial (NTM) disease. The authors have evaluated the evidence for the position of amikacin in NTM disease treatment.
J. Raaijmakers   +3 more
semanticscholar   +1 more source

Effects of amikacin, polymyxin-B, and sulbactam combination on the pharmacodynamic indices of mutant selection against multi-drug resistant Acinetobacter baumannii

open access: yesFrontiers in Microbiology, 2022
Amikacin and polymyxins as monotherapies are ineffective against multidrug-resistant Acinetobacter baumannii at the clinical dose. When polymyxins, aminoglycosides, and sulbactam are co-administered, the combinations exhibit in vitro synergistic ...
Shixing Zhu   +11 more
doaj   +1 more source

Population Pharmacokinetic Evaluation of Amikacin Liposome Inhalation Suspension in Patients with Treatment-Refractory Nontuberculous Mycobacterial Lung Disease

open access: yesEuropean journal of drug metabolism and pharmacokinetics, 2021
Use of parenteral amikacin to treat refractory nontuberculous mycobacterial (NTM) lung disease is limited by systemic toxicity. A population pharmacokinetic model was developed using data pooled from two randomized trials to evaluate the pharmacokinetic ...
C. Rubino   +7 more
semanticscholar   +1 more source

Evaluating the Efficacy of Eravacycline and Omadacycline against Extensively Drug-Resistant Acinetobacter baumannii Patient Isolates

open access: yesAntibiotics, 2022
For decades, the spread of multidrug-resistant (MDR) Acinetobacter baumannii has been rampant in critically ill, hospitalized patients. Traditional antibiotic therapies against this pathogen have been failing, leading to rising concerns over management ...
Manas S. Deolankar   +5 more
doaj   +1 more source

Analysis of Phenotypic and Genotypic Susceptibility to Clarithromycin and Amikacin of Mycobacterium abscessus Complex Strains Isolated from Cystic Fibrosis Patients

open access: yesMicroorganisms, 2023
Mycobacterium abscessus complex infections are ever on the rise. To curb their increasing evolution, we performed an in-depth study of 43 clinical isolates of cystic fibrosis patients obtained from 2009 to 2020.
Juan Carlos Cao Yao   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy