Results 41 to 50 of about 145,366 (199)

Amikacin and renal Impairment: optimized dosing regimens by pharmacokinetic simulation according to KDIGO Stages. [PDF]

Batna Journal of Medical Sciences
Introduction: Pharmacokinetic simulations enable evaluation of the impact of dosing regimens and administration intervals on the achievement of therapeutic targets for amikacin, particularly in patients with renal impairment.
Fatima Zohra BOUAOUA, Karim BOULESBIAAT, Houari TOUMI, Pierre MARQUET, Sihem ZITOUNI, Sabah BENBOUDIAF, Soumia BOUDJEMAA, moufida GHARBI, Hocine GACEM, Haroune BOUAB, Nouar BOUDJOUREF, Nadia BOULEKHAL, Zoulikha BENHACINE, Zahra OUCHNENE, Zahia HAZMOUNE, Khaled BOUZENDA, Zakaria BOUREZAK, Abd El Jalil LALAOUNA, Mehdi GUEROUI, Nacer KHARNANE, Chaouki DERDOUS, Zahia BENABID, Linda AIMEUR, LAMARA Malika   +23 more
doaj   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

Cystitis in guinea pigs (Cavia porcellus): Clinical findings and treatment outcomes

Veterinary Record, EarlyView.
Abstract Background This retrospective study examined the incidence, diagnostic methods, bacterial isolates, treatments and outcomes associated with cystitis in guinea pigs presented at a single clinic between 2009 and 2022. Methods The clinic's medical records database was reviewed using easyvet software to identify cases eligible for inclusion in the
Anika Mische, Kerstin Müller
wiley   +1 more source

Renal Impact of a High-Loading Dose of Amikacin in Critically Ill Patients [PDF]

Pharmaceutical Sciences
Background: Aminoglycosides are potent bactericidal antibiotics primarily employed for gram-negative infections. However, they face limitations due to potential renal toxicity when administered at high doses. This study aimed to assess the nephrotoxicity
Laleh Mahmoudi, Arezoo Ahmadi, Motahareh Mahi-Birjand, Effat Alemzadeh, Parvin Askari, Ramin Niknam, Mojtaba Mojtahedzadeh   +6 more
doaj   +1 more source

Aminoglycoside trough levels in neonates [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2010
Introduction. Drug safety depends on trough levels. Objective. Objective of the study was to measure gentamicin and amikacin trough levels in neonates and to identify risk groups by gestational and postnatal age. Methods.
Pejović Biljana, Ranković-Janevski Milica, Božinović-Prekajski Niveska   +2 more
doaj   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

VIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe, Satish Rojekar, Amol Gholap, K. Navaneetha Pandiyaraj, Mukesh Patekar, Claudia Riccardi, R. R. Deshmukh, Tomáš Kovářík, Kalim Deshmukh   +8 more
wiley   +1 more source

Therapeutic drug monitoring in peritoneal dialysis: A case of nontuberculous mycobacterium catheter‐related infection treated with amikacin

Clinical Case Reports, 2020
The pharmacokinetics of amikacin makes it difficult to predict the appropriate dosing to avoid harmful side effects in patients undergoing continuous ambulatory peritoneal dialysis (CAPD).
Sanae Kojya, Hideo Shiohira, Yoshitsugu Sunagawa, Shoji Tsuneyoshi, Kentaro Kohagura, Yusuke Ohya, Fusako Yonaha, Nobuo Hokama, Katsunori Nakamura   +8 more
doaj   +1 more source

Long‐term outcomes of gastric bypass surgery in two Lusitano foals: Contemporary evidence for surgical decision‐making

Equine Veterinary Education, EarlyView.
Summary Gastric outflow obstruction (GOO) occasionally requires surgical intervention in foals when medical management fails. Current literature lacks consensus on several surgical decisions, with most comprehensive reports dating back over a decade. Critical aspects—including jejunal loop orientation and necessity of jejunojejunostomy—remain debated ...
P. Fernández Hernández, M. Valero González, F. Bulnes Jiménez, N. Venegas Chávez, B. Fuentes Romero, M. Iglesias García, J. Jiménez Fragoso, M. Martín Cuervo, L. J. Ezquerra Calvo   +8 more
wiley   +1 more source

Resensitization of Fluconazole-Resistant Urinary Candida spp. Isolates by Amikacin through Downregulation of Efflux Pump Genes [PDF]

Polish Journal of Microbiology, 2020
EVA A. EDWARD, NELLY M. MOHAMED, AZZA S. ZAKARIA   +2 more
doaj   +1 more source

Update on innovative surgical techniques for omphalectomy in foals

Equine Veterinary Education, EarlyView.
Summary Umbilical infection is a common foal disorder, prone to complications, requiring surgical excision in severe cases. Timely surgical excision is the treatment of choice in these cases, as the infected umbilicus places the foal at risk for further fatal complications, such as sepsis and septic arthritis.
O. Haion, A. J. Tatz, R. Dahan, G. Kelmer   +3 more
wiley   +1 more source