Results 41 to 50 of about 205,880 (261)

Rapid Detection of Clarithromycin and Amikacin Resistance in Mycobacterium abscessus Complex by High-Resolution Melting Curve Analysis

Microbiology Spectrum, 2022
The emergence of Mycobacterium abscessus complex (MABC) infection is the most noteworthy health care problem. Clarithromycin (CLA) and amikacin (AMK) constitute the cornerstone of treatment for patients infected with MABC; thus, early detection of ...
Haoran Li, Gulibike Mulati, Yuanyuan Shang, Cong Yao, Yufeng Wang, Weicong Ren, Zhongtan Xue, Shanshan Li, Yu Pang   +8 more
doaj   +1 more source

Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]

, 2017
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi, Ami G. Shah, Anderson, Arlt, Barr, Barthelemy, Beiderlinden, Bein, Bembea, Bhatt-Meht, Boucher, Brandi N. Thoma, Brown, Buck, Buscher, Chung, Dagan, Dagan, de Montmollin, De Rosa, DeGrado, Donadello, Donadello, Dzierba, Erstad, Esper, Eyler, Flordelis Lasierra, Glauber, Greenberg, Gélisse, Hadidi, Hertzog, Hraiech, Hynynen, Johnston, Kawada, Kim, Koster, Krueger, Lamarche, Latronico, Lemaitre, Levison, Malfertheiner, Mehta, Michelle Peahota, Moore, Mousavi, Mulla, Mulla, Muntean, Oliver, Paden, Park, Perkins, Peters, Pettignano, Phillips, Pieri, Potter, Preston, Protti, Ranucci, Riker, Roberts, Roos, Rosen, Ruiz, Rybak, Saini, Sanfilippo, Satyapriya, Schmith, Shekar, Shekar, Shekar, Shekar, Shekar, Sherwin, Sklar, Smith, Spriet, Staudacher, Strunk, Subramaniam, Szefner, Tellor, Trudzinski, Tulman, Turner, Veinstein, Vilay, Wagner, Walter K. Kraft, Welsch, Wen, Wildschut, Wu, Young   +99 more
core   +2 more sources

Association between 16S rRNA gene mutations and susceptibility to amikacin in Mycobacterium avium Complex and Mycobacterium abscessus clinical isolates

Scientific Reports, 2020
We evaluated the association between 16S rRNA gene (rrs) mutations and susceptibility in clinical isolates of amikacin-resistant nontuberculous mycobacteria (NTM) in NTM-pulmonary disease (PD) patients.
Su-Young Kim, Dae Hun Kim, S. Moon, J. Song, H. Huh, N. Lee, S. Shin, W. Koh, B. W. Jhun   +8 more
semanticscholar   +1 more source

Nebulized Antibiotics for Preventing and Treating Gram-Negative Respiratory Infections in Critically Ill Patients: An Overview of Reviews

Antibiotics
Background. Ventilator-associated tracheobronchitis (VAT) and pneumonia (VAP) are the most frequent nosocomial infections in the critical care setting and are associated with increased morbidity. At the same time, VAP is also associated with attributable
Marios Karvouniaris, Despoina Koulenti, Konstantinos I. Bougioukas, Eirini Pagkalidou, Elizabeth Paramythiotou, Anna-Bettina Haidich   +5 more
doaj   +1 more source

Mycobacterium ulcerans infection: control, diagnosis, and treatment. [PDF]

, 2006
The skin disease Buruli ulcer, caused by Mycobacterium ulcerans, is the third most common mycobacterial disease after tuberculosis and leprosy and mainly affects remote rural African communities. Although the disease is known to be linked to contaminated
Adjei, Amofah, Amofah, Andries, Aujoulat, Bentoucha, Darie, Debacker, Debacker, Debacker, Dega, Dega, Dhople, Dhople, Dhople, Drummond, Eddyani, Eric Comte, Espey, Etuaful, Evans, Evans, Fabienne Nackers, Fehr, Françoise Portaels, Guédénon, Hospers, Huygen, Johnson, Johnson, Johnson, Kanga, Kanga, Kanga, Klutse, Marsollier, Marsollier, Marsollier, Marsollier, Marsollier, Marston, Meyers, Mve-Obiang, Nakanaga, Noeske, Okenu, Phillips, Phillips, Portaels, Pszolla, Raghunathan, Revill, Rhodes, Scott, Siegmund, Smith, Stienstra, Stienstra, Stragier, Tanghe, Thangaraj, van der Werf, van der Werf, Veitch, Vinciane Sizaire   +64 more
core   +2 more sources

Amikacin Liposome Inhalation Suspension (ALIS) Penetrates Non-tuberculous Mycobacterial Biofilms and Enhances Amikacin Uptake Into Macrophages

Frontiers in Microbiology, 2018
Non-tuberculous mycobacteria (NTM) cause pulmonary infections in patients with structural lung damage, impaired immunity, or other risk factors. Delivering antibiotics to the sites of these infections is a major hurdle of therapy because pulmonary NTM ...
Jimin Zhang, F. Leifer, S. Rose, D. Y. Chun, Jill Thaisz, Tracey Herr, M. Nashed, J. Joseph, W. Perkins, K. Dipetrillo   +9 more
semanticscholar   +1 more source

Dual Antibiotic-Infused Liposomes to Control Methicillin-Resistant Staphylococcus aureus

Medicines
Background: Methicillin-resistant Staphylococcus aureus (MRSA) considered under the category of serious threats by the Centers for Disease Control and Prevention (CDC), urges for new antibiotics or alternate strategies to control MRSA.
Sourav Chakraborty, Piyush Baindara, Surojit Das, Suresh K. Mondal, Pralay Sharma, Austin Jose T, Kumaravel V, Raja Manoharan, Santi M. Mandal   +8 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

In Vitro Antibacterial Activity of Silver Nanoparticles Conjugated with Amikacin and Combined with Hyperthermia against Drug-Resistant and Biofilm-Producing Strains

Microbiology Spectrum, 2023
In view of the current increase and spread of antimicrobial resistance (AMR), there is an urgent need to find new strategies to combat it. This study had two aims.
Marta Palau, Estela Muñoz, Muriel F. Gusta, Nieves Larrosa, Xavier Gomis, Joan Gilabert, Benito Almirante, Victor Puntes, Robert Texidó, Joan Gavaldà   +9 more
doaj   +1 more source

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss

Advanced Science, EarlyView.
 . ABSTRACT Sensorineural hearing loss (SNHL) induced by noise or aminoglycoside antibiotics is a significant public health concern without any FDA‐approved pharmaceutical therapies. Dysregulation of iron homeostasis and its subsequently induced ferroptosis has increasingly been identified as a key mechanism underlying cochlear hair cell (HC) damage ...
Huanyu Mao, Xiang Li, Yaqi Liao, Liman Liu, Xian Gao, Hailiang Lin, Wenli Ni, Huawei Li, Yan Chen, Wenyan Li   +9 more
wiley   +1 more source