Results 121 to 130 of about 67,576 (269)

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

Antiglycation, radical scavenging, and semicarbazide-sensitive amine oxidase inhibitory activities of acetohydroxamic acid in vitro

Drug Design, Development and Therapy, 2017
Yuh-Hwa Liu,1,2,* Yeh-Lin Lu,3,* Der-Zen Liu,4 Wen-Chi Hou5 1Division of Gastroenterology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan; 2Department of General Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; 3Department
Liu YH, Lu YL, Liu DZ, Hou WC
doaj  

Biocatalytic cascade to polysaccharide amination

Biotechnology for Biofuels and Bioproducts
Background Chitin, the main form of aminated polysaccharide in nature, is a biocompatible, polycationic, and antimicrobial biopolymer used extensively in industrial processes.
Xuebin Feng, Siyi Hong, Hongbo Zhao, Thu V. Vuong, Emma R. Master   +4 more
doaj   +1 more source

The Impact of Semicarbazide Sensitive Amine Oxidase Activity on Rat Aortic Vascular Smooth Muscle Cells. [PDF]

Int J Mol Sci, 2023
Manasieva V, Thakur S, Lione LA, Baydoun AR, Skamarauskas J.   +4 more
europepmc   +1 more source

Preclinical models for evaluating psychedelics in the treatment of major depressive disorder

British Journal of Pharmacology, EarlyView.
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander, Dasha Anderson, Luke Baxter, Matthew Claydon, James Rucker, Emma S. J. Robinson   +5 more
wiley   +1 more source

A randomised Phase IIa trial of amine oxidase copper-containing 3 (AOC3) inhibitor BI 1467335 in adults with non-alcoholic steatohepatitis. [PDF]

Nat Commun, 2023
Newsome PN, Sanyal AJ, Neff G, Schattenberg JM, Ratziu V, Ertle J, Link J, Mackie A, Schoelch C, Lawitz E, BI 1467335 NASH Phase IIa trial team.   +10 more
europepmc   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

British Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Immobilization of Lathyrus cicera Amine Oxidase on Magnetic Microparticles for Biocatalytic Applications. [PDF]

Int J Mol Sci, 2022
Di Fabio E, Iazzetti A, Incocciati A, Caseli V, Fabrizi G, Boffi A, Bonamore A, Macone A.   +7 more
europepmc   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder

Clinical &Experimental Allergy, EarlyView.
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Matija Rijavec, Žan Kogovšek, Jezerka Inkret, Peter Kopač, Mitja Košnik, Peter Korošec   +5 more
wiley   +1 more source

The enzyme pseudooxynicotine amine oxidase from Pseudomonas putida S16 is not an oxidase, but a dehydrogenase. [PDF]

J Biol Chem, 2022
Choudhary V, Wu K, Zhang Z, Dulchavsky M, Barkman T, Bardwell JCA, Stull F.   +6 more
europepmc   +1 more source