Results 201 to 210 of about 22,060 (235)

The effects of buffer cations on interactions between mammalian copper-containing amine oxidases and their substrates

Journal of Neural Transmission, 2007
We and others have observed that substrates for copper-containing amine oxidases cause substrate inhibition at high concentrations. Through use of a novel "pseudoquantitative" rapid equilibrium approach, kinetic analyses with human and bovine enzymes indicate that these effects are consistent with substrates binding to oxidised and reduced enzyme forms.
HOLT A, DEGENHARDT OS, BERRY PD, KAPTY JS, MITHANI S, SMITH DJ, DI PAOLO, MARIA LUISA   +6 more
openaire   +2 more sources

Towards the development of selective amine oxidase inhibitors

European Journal of Biochemistry, 2002
Four substrate analogs, 4‐(2‐naphthyloxy)‐2‐butyn‐1‐amine (1), 1,4‐diamino‐2‐chloro‐2‐butene (2), 1,6‐diamino‐2,4‐hexadiyne (3), and 2‐chloro‐5‐phthalimidopentylamine (4) have been tested as inhibitors against mammalian, plant, bacterial, and fungal copper‐containing amine oxidases: bovine plasma amine oxidase (BPAO), equine plasma amine oxidase (EPAO),
Eric M, Shepard, Jennifer, Smith, Bradley O, Elmore, Jason A, Kuchar, Lawrence M, Sayre, David M, Dooley   +5 more
openaire   +2 more sources

Characterization of Arabidopsis insertional mutants for copper-containing amine oxidases

2010
In plants, polyamines are catabolised by amine oxidases, which are present in different sub-cellular compartments. The chemical identity of AO-catalyzed reaction products depends on mode of polyamine oxidation, hydrogen peroxide representing a shared compound in all the AO-mediated reactions.
ALESSANDRA TISI, PARASKEVI TAVLADORAKI, RODRIGUES POUSADA, RENATO ALBERTO, RODOLFO FEDERICO, RICCARDO ANGELINI, ALESSANDRA CONA   +5 more
openaire   +2 more sources

3-hydrazinopyridazine derivatives as inhibitors of the copper containing amine oxidases.

Il Farmaco; edizione scientifica, 1977
A series of 3-hydrazine derivatives with antihypertensive properties were studied as inhibitors of the copper containing amine oxidases. All the compounds with a free hydrazino group were found to be strong-non-competitive inhibitors. Some of them had an inhibitory activity of the same order as that of hydralazine.
F, Buffoni, G, Ignesti, R, Pirisino
openaire   +1 more source

[Copper-containing amine oxidases of blood vessels (review of the literature)].

Voprosy meditsinskoi khimii, 1987
Modern data on types, physico-chemical properties, physiological role of copper-containing amine oxidase of blood vessels are reviewed. Properties of lysyl oxidase--specific copper-containing amine oxidase--are described. Importance of the enzyme for normal functions of connective tissue as well as alterations in the enzymatic activity under various ...
Z B, Megrabian, R M, Nalbandian
openaire   +1 more source

ω‐(5‐Phenyl‐2H‐tetrazol‐2‐yl)alkyl‐substituted hydrazides and related compounds as inhibitors of amine oxidase copper containing 3 (AOC3)

Archiv Der Pharmazie, 2022
Matthias Lehr
exaly  

Amine oxidase copper‐containing 3 aggravates cardiac remodelling by generating hydrogen peroxide after myocardial infarction

Journal of Pathology, 2023
Chong-Bin Zhong, Dongdong Que, Pingzhen Yang   +2 more
exaly  

Amine oxidase (copper-containing)

1993
Dietmar Schomburg, Margit Salzmann, Dörte Stephan   +2 more
openaire   +1 more source

The Copper-Containing Amine Oxidases: Biochemical Aspects and Functional Role

Molecular Genetics and Metabolism, 2000
F, Buffoni, G, Ignesti
openaire   +2 more sources

Structure and function of copper-containing amine oxidases

Inflammation Research, 2001
openaire   +2 more sources