Crystallization of a truncated soluble human semicarbazide-sensitive amine oxidase [PDF]
Acta Crystallographica Section F: Structural Biology Communications, 2005 Human semicarbazide-sensitive amine oxidase (SSAO) is a homodimeric copper-containing monoamine oxidase that occurs in both a membrane-bound and a soluble form. SSAO is also known as vascular adhesion protein-1 (VAP-1). A truncated soluble form of human SSAO (comprising residues 29-763) was expressed in human embryonic kidney 293 cells and purified to ...
Gérard J Kleywegt, Kleywegt G J
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Serum level of semicarbazide-sensitive amine oxidase in children with ADHD. [PDF]
Behav Brain Funct, 2006 AbstractBackgroundThe objective of this study was to analyze the extracellularly acting semicarbazide-sensitive amine oxidase (SSAO) serum levels in children with ADHD for the first time. SSAO is known to show deviations from normal in various somatic disorders and to interplay with the intracellularly active MAO.
Roessner V +5 more
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Origins of Serum Semicarbazide-Sensitive Amine Oxidase [PDF]
Circulation Research, 2004 Semicarbazide-sensitive amine oxidases (SSAO) are enzymes that are capable of deaminating primary amines to produce aldehyde, ammonia, and hydrogen peroxide. This activity has been associated with vascular adhesion protein-1 (VAP-1) and is found in the serum, endothelium, adipose, and smooth muscle of mammals.
Craig M, Stolen +5 more
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Allosteric modulation of semicarbazide-sensitive amine oxidase activities in vitro by imidazoline receptor ligands [PDF]
British Journal of Pharmacology, 2004 exaly +2 more sources
Molecular Cloning and Characterization of Rat Semicarbazide-Sensitive Amine Oxidase
Biological and Pharmaceutical Bulletin, 2005 Semicarbazide-sensitive amine oxidase (SSAO) (EC 1.4.3.6) is widely distributed in nature and catalyzes the oxidative deamination of primary amines. Although SSAO full-length cDNA sequences have been reported for some mammalian species, only a partial 5'-terminal sequence has been confirmed in the rat.
Ochiai, Yoshinori +3 more
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Properties of a Semicarbazide-Sensitive Amine Oxidase in Human Umbilical Artery
Journal of Pharmacy and Pharmacology, 1988 Abstract The metabolism of some aromatic amines by amine oxidase activities in human umbilical artery homogenates has been studied. The inhibitory effects of clorgyline showed that 5-hydroxytryptamine (5-HT) and tryptamine, 1 mM, were predominantly substrates for monoamine oxidase (MAO) type A, whereas MAO-A and B were both involved in ...
E, Precious, G A, Lyles
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The Impact of Semicarbazide Sensitive Amine Oxidase Activity on Rat Aortic Vascular Smooth Muscle Cells. [PDF]
Int J Mol Sci, 2023 Manasieva V +4 more
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The Biological Implication of Semicarbazide-Sensitive Amine Oxidase (SSAO) Upregulation in Rat Systemic Inflammatory Response under Simulated Aerospace Environment. [PDF]
Int J Mol Sci, 2023 Yan L +9 more
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Semicarbazide-Sensitive Amine Oxidase (SSAO) and Lysyl Oxidase (LOX) Association in Rat Aortic Vascular Smooth Muscle Cells. [PDF]
Biomolecules, 2022 Manasieva V +5 more
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Vascular Adhesion Protein-1 (VAP-1)/Semicarbazide-Sensitive Amine Oxidase (SSAO): A Potential Therapeutic Target for Atherosclerotic Cardiovascular Diseases. [PDF]
Front Pharmacol, 2021 Li H, Du S, Niu P, Gu X, Wang J, Zhao Y.
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