Results 21 to 30 of about 2,006 (201)

Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1

Mediators of Inflammation, 2020
Vascular adhesion protein-1 (VAP-1) is an ectoenzyme that functions as a copper-containing amine oxidase and is involved in leukocyte adhesion at sites of inflammation.
Ryo Kubota, Michael J. Reid, Kuo Lee Lieu, Mark Orme, Christine Diamond, Niklas Tulberg, Susan H. Henry   +6 more
doaj   +2 more sources

Red-light photobiomodulation improves cognition and neuropsychiatric symptoms in post-stroke cognitive impairment: a randomized trial [PDF]

Frontiers in Neurology
IntroductionAcute stroke patients often develop post-stroke cognitive impairment (PSCI) and dysthymic disorders. Formaldehyde (FA) induces cognitive decline and depression; while red light (RL) at 630 nm can degrade FA by activating FA-dehydrogenase (FDH)
Xuerong Huang, Xuerong Huang, Xuerong Huang, Zihui Sun, Zihui Sun, Zihui Sun, Weijie Wu, Linli Lou, Panpan Wang, Qin Wang, Yuanyu Fu, Liange Xu, Mengwan Song, Lidong Zhu, Jin Huang, Shaobo Ni, Guangyong Chen, Xueping Liu, Xueping Liu, Zhiqian Tong, Zhiqian Tong   +20 more
doaj   +2 more sources

Semicarbazide diminishes the signs of bleomycin-induced pulmonary fibrosis in rats [PDF]

The Ukrainian Biochemical Journal, 2021
The pathogenesis of pulmonary fibrosis (PF) is accompanied by extracellular matrix (ECM) deposition, oxidative stress, and inflammation progression, as well as hyperactivation of amine oxidases (AOs), which contribute to disease manifestation.
O. O. Hudkova, I. P. Krysiuk, T. O. Kishko, N. M. Popova, L. B. Drobot, N. V. Latyshko   +5 more
doaj   +1 more source

Rhabdomyolysis attenuates activity of semicarbazide sensitive amine oxidase as the marker of nephropathy in diabetic rats [PDF]

The Ukrainian Biochemical Journal, 2022
Amine oxidases are involved in the progression of many diseases and their complications, including renal failure, due to the generation of the three toxic metabolites (H2O2, aldehydes, and ammonia) in the course of biogenic amines oxidative deamination ...
O. Hudkova, I. Krysiuk, L. Drobot, N. Latyshko   +3 more
doaj   +1 more source

Amine oxidases as important agents of pathological processes of rhabdomyolysis in rats [PDF]

The Ukrainian Biochemical Journal, 2016
In this study we have tested an idea on the important role of amine oxidases (semicarbazide-sensitive amine oxidase, diamine oxidase, polyamine oxidase) as an additional source of oxidative/carbonyl stress under glycerol-induced rhabdomyolysis, since the
O. O. Gudkova, N. V. Latyshko, S. G. Shandrenko   +2 more
doaj   +1 more source

New Data on Cylindrospermopsin Toxicity

Toxins, 2021
Cylindrospermopsin (CYN) is a widely spread cyanotoxin that can occur in fresh water and food. This research aims to investigate CYN toxicity by studying the effects of drinking 0.25 nM of CYN-contaminated water from a natural source, and of the direct ...
Mariela Chichova, Oskan Tasinov, Milena Shkodrova, Milena Mishonova, Iliyana Sazdova, Bilyana Ilieva, Dilyana Doncheva-Stoimenova, Yoana Kiselova-Kaneva, Neli Raikova, Blagoy Uzunov, Diana Ivanova, Hristo Gagov   +11 more
doaj   +1 more source

Zinc-α2-glycoprotein as an inhibitor of amine oxidase copper-containing 3 [PDF]

Open Biology, 2020
Zinc-α2-glycoprotein (ZAG) is a major plasma protein whose levels increase in chronic energy-demanding diseases and thus serves as an important clinical biomarker in the diagnosis and prognosis of the development of cachexia.
Matthias Romauch
doaj   +1 more source

Origins of Serum Semicarbazide-Sensitive Amine Oxidase [PDF]

Circulation Research, 2004
Semicarbazide-sensitive amine oxidases (SSAO) are enzymes that are capable of deaminating primary amines to produce aldehyde, ammonia, and hydrogen peroxide. This activity has been associated with vascular adhesion protein-1 (VAP-1) and is found in the serum, endothelium, adipose, and smooth muscle of mammals.
Craig M, Stolen, Gennady G, Yegutkin, Riikka, Kurkijärvi, Petri, Bono, Kari, Alitalo, Sirpa, Jalkanen   +5 more
openaire   +2 more sources

A detection model for cognitive dysfunction based on volatile organic compounds from a large Chinese community cohort

Alzheimer's &Dementia, Volume 19, Issue 11, Page 4852-4862, November 2023., 2023
Abstract Introduction We explored whether volatile organic compound (VOC) detection can serve as a screening tool to distinguish cognitive dysfunction (CD) from cognitively normal (CN) individuals. Methods The cognitive function of 1467 participants was assessed and their VOCs were detected.
Bin Jiao, Sizhe Zhang, Yuzhang Bei, Guiwen Bu, Li Yuan, Yuan Zhu, Qijie Yang, Tianyan Xu, Lu Zhou, Qianqian Liu, Ziyu Ouyang, Xuan Yang, Yong Feng, Beisha Tang, Haibin Chen, Lu Shen   +15 more
wiley   +1 more source

Genomic and experimental evidence for multiple metabolic functions in the RidA/YjgF/YER057c/UK114 (Rid) protein family. [PDF]

, 2015
BackgroundIt is now recognized that enzymatic or chemical side-reactions can convert normal metabolites to useless or toxic ones and that a suite of enzymes exists to mitigate such metabolite damage.
Cooper, Arthur JL, Downs, Diana M, ElBadawi-Sidhu, Mona, Fiehn, Oliver, Gerdes, Svetlana, Hanson, Andrew D, Hodge-Hanson, Kelsey, Niehaus, Thomas D, Zhukov, Aleksey   +8 more
core   +4 more sources