Results 31 to 40 of about 1,805,611 (181)

Recent advances in nanomaterial‐assisted electrochemical sensors for food safety analysis

open access: yesFood Frontiers, Volume 3, Issue 3, Page 453-479, September 2022., 2022
This review focuses on current research achievements of nanomaterial‐assisted electrochemical sensors for food safety analysis reported in recent years. It highlights the different detection mechanisms for analytes, flexible sensing strategies based on nanomaterials, and portable miniaturized electrochemical devices.
Ying Gu   +6 more
wiley   +1 more source

ω‐(5‐Phenyl‐2H‐tetrazol‐2‐yl)alkyl‐substituted hydrazides and related compounds as inhibitors of amine oxidase copper containing 3 (AOC3)

open access: yesArchiv der Pharmazie, Volume 355, Issue 8, August 2022., 2022
Inhibitors of amine oxidase copper containing 3 (AOC3) could be created by replacement of the amine functionality of the tight‐binding substrate 6‐(5‐phenyl‐2H‐tetrazol‐2‐yl)hexan‐1‐amine (1) by hydrazide, glycine amide, and structurally related moieties.
Florian Galster   +3 more
wiley   +1 more source

Acute high‐altitude hypoxia exposure causes neurological deficits via formaldehyde accumulation

open access: yesCNS Neuroscience &Therapeutics, Volume 28, Issue 8, Page 1183-1194, August 2022., 2022
Proposed molecular mechanism of acute hypobaric hypoxia induced neurological deficits via formaldehyde accumulation. AHH, acute hypobaric hypoxia; MA, methylamine; SSAO, semicarbazide‐sensitive amine oxidase; FA, formaldehyde; ALDH2, aldehyde dehydrogenase 2; H2O, water; CO2, carbon dioxide; GSH, glutathione; GPx4, glutathione peroxidase 4; LPO, lipid ...
Xiaoyin Wang   +6 more
wiley   +1 more source

Single‐cell transcriptional profiling of human carotid plaques reveals a subpopulation of endothelial cells associated with stroke incidences

open access: yesJournal of Cellular and Molecular Medicine, Volume 26, Issue 12, Page 3446-3459, June 2022., 2022
Abstract The differences in plaque histology between symptomatic and asymptomatic patients have been widely accepted. Whether there is a heterogeneity of cells between symptomatic and asymptomatic plaques remains largely unclear. To reveal the potential heterogeneity within different plaques, which may contribute to different stroke incidences, we ...
Fengchan Li   +9 more
wiley   +1 more source

Presence of nitrofurans and their metabolites in gelatine

open access: yesEFSA Journal, Volume 19, Issue 10, October 2021., 2021
Abstract Following the detection of semicarbazide (SEM) in gelatine by Italian Authorities, at levels exceeding by three times the reference point for action (RPA) of 1 μg/kg, set out by Commission Regulation (EU) 2019/1871 for nitrofurans and their metabolites, the European Commission mandated EFSA to investigate the available sources of nitrofurans ...
European Food Safety Authority (EFSA)   +3 more
wiley   +1 more source

The cellular function and molecular mechanism of formaldehyde in cardiovascular disease and heart development

open access: yesJournal of Cellular and Molecular Medicine, Volume 25, Issue 12, Page 5358-5371, June 2021., 2021
Abstract As a common air pollutant, formaldehyde is widely present in nature, industrial production and consumer products. Endogenous formaldehyde is mainly produced through the oxidative deamination of methylamine catalysed by semicarbazide‐sensitive amine oxidase (SSAO) and is ubiquitous in human body fluids, tissues and cells.
Ying Zhang   +8 more
wiley   +1 more source

Past, Present and Future Anti-Obesity Effects of Flavin-Containing and/or Copper-Containing Amine Oxidase Inhibitors

open access: yesMedicines, 2019
Background: Two classes of amine oxidases are found in mammals: those with a flavin adenine dinucleotide as a cofactor, such as monoamine oxidases (MAO) and lysine-specific demethylases (LSD), and those with copper as a cofactor, including copper ...
Christian Carpéné   +3 more
doaj   +1 more source

Structural analysis and biochemical properties of laccase enzymes from two Pediococcus species

open access: yesMicrobial Biotechnology, Volume 14, Issue 3, Page 1026-1043, May 2021., 2021
Prokaryotic laccases are emergent biocatalysts. However, they have not been broadly found and characterized in bacterial organisms, especially in lactic acid bacteria. Recently, a prokaryotic laccase from the lactic acid bacterium Pediococcus acidilactici 5930, which can degrade biogenic amines, was discovered.
Isidoro Olmeda   +8 more
wiley   +1 more source

Semicarbazide-sensitive amine oxidase activity levels in patients with acute lymphoblastic leukemia after cytotoxic chemotherapy

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2018
Background: The role of Semicarbazide-sensitive amine oxidase (SSAO) in carcinogenesis is unknown; however, due to its function it may be involved in tumorigenesis via production of reactive aldehydes and hydrogen peroxide.
Shatha Abdul Wadood AL‑Shammaree
doaj   +1 more source

Inhibition of vascular adhesion protein‐1 enhances the anti‐tumor effects of immune checkpoint inhibitors

open access: yesCancer Science, Volume 112, Issue 4, Page 1390-1401, April 2021., 2021
In this study, we have identified the involvement of H2O2, an enzymatic product of vascular adhesion protein‐1, as a new mechanism for the generation of an immunosuppressive tumor microenvironment in murine tumor models and some human cancers.
Tomonari Kinoshita   +9 more
wiley   +1 more source

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