Results 41 to 50 of about 2,006 (201)

Structural analysis and biochemical properties of laccase enzymes from two Pediococcus species

open access: yesMicrobial Biotechnology, Volume 14, Issue 3, Page 1026-1043, May 2021., 2021
Prokaryotic laccases are emergent biocatalysts. However, they have not been broadly found and characterized in bacterial organisms, especially in lactic acid bacteria. Recently, a prokaryotic laccase from the lactic acid bacterium Pediococcus acidilactici 5930, which can degrade biogenic amines, was discovered.
Isidoro Olmeda   +8 more
wiley   +1 more source

Inhibition of vascular adhesion protein‐1 enhances the anti‐tumor effects of immune checkpoint inhibitors

open access: yesCancer Science, Volume 112, Issue 4, Page 1390-1401, April 2021., 2021
In this study, we have identified the involvement of H2O2, an enzymatic product of vascular adhesion protein‐1, as a new mechanism for the generation of an immunosuppressive tumor microenvironment in murine tumor models and some human cancers.
Tomonari Kinoshita   +9 more
wiley   +1 more source

Past, Present and Future Anti-Obesity Effects of Flavin-Containing and/or Copper-Containing Amine Oxidase Inhibitors

open access: yesMedicines, 2019
Background: Two classes of amine oxidases are found in mammals: those with a flavin adenine dinucleotide as a cofactor, such as monoamine oxidases (MAO) and lysine-specific demethylases (LSD), and those with copper as a cofactor, including copper ...
Christian Carpéné   +3 more
doaj   +1 more source

Semicarbazide-sensitive amine oxidase activity levels in patients with acute lymphoblastic leukemia after cytotoxic chemotherapy

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2018
Background: The role of Semicarbazide-sensitive amine oxidase (SSAO) in carcinogenesis is unknown; however, due to its function it may be involved in tumorigenesis via production of reactive aldehydes and hydrogen peroxide.
Shatha Abdul Wadood AL‑Shammaree
doaj   +1 more source

Ferricytochrome c Directly Oxidizes Aminoacetone to Methylglyoxal, a Catabolite Accumulated in Carbonyl Stress [PDF]

open access: yes, 2013
Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine catabolite, is reportedly known to undergo metal-catalyzed oxidation to methylglyoxal, NH4 ...
Bechara, Etelvino José Henriques   +8 more
core   +6 more sources

Endothelial cell-derived SSAO can increase MLC20 phosphorylation in VSMCs

open access: yesOpen Life Sciences, 2021
Vascular hyporesponsiveness in the shock decompensation period is an important factor leading to death. Myosin light chain 20 (MLC20) is the main effector protein that regulates vascular reactivity.
Zhang Yuxing   +5 more
doaj   +1 more source

Copper-dependent amino oxidase 3 governs selection of metabolic fuels in adipocytes. [PDF]

open access: yesPLoS Biology, 2018
Copper (Cu) has emerged as an important modifier of body lipid metabolism. However, how Cu contributes to the physiology of fat cells remains largely unknown.
Haojun Yang   +9 more
doaj   +1 more source

Effects of Chemical Structures Interacting with Amine Oxidases on Glucose, Lipid and Hydrogen Peroxide Handling by Human Adipocytes

open access: yesMolecules, 2022
Benzylamine is a natural molecule present in food and edible plants, capable of activating hexose uptake and inhibiting lipolysis in human fat cells.
Christian Carpéné   +6 more
doaj   +1 more source

Potential role of NADPH-oxidase in early steps of lead-induced oxidative burst in Vicia faba roots [PDF]

open access: yes, 2008
The mechanism of oxidative burst induced by lead in Vicia faba excised roots was investigated by luminol-dependent chemiluminescence. Results showed that lead triggered a rapid and dose-dependent increase in chemiluminescence production.
Cecchi, Marie   +5 more
core   +3 more sources

Amine oxidase copper-containing 3 (AOC3) inhibition: a potential novel target for the management of diabetic retinopathy

open access: yesInternational Journal of Retina and Vitreous, 2021
Background Diabetic retinopathy (DR), a microvascular complication of diabetes, is the leading cause of visual impairment in people aged 20–65 years and can go undetected until vision is irreversibly lost.
David S. Boyer   +5 more
doaj   +1 more source

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