Results 21 to 30 of about 7,123 (216)

Zinc-α2-Glycoprotein Is An Inhibitor Of Amine Oxidase Copper-Containing 3 [PDF]

Open Biology, 2019
AbstractZinc-alpha2-glycoprotein (ZAG) is a major plasma protein whose levels increase in chronic energy-demanding diseases and thus serves as an important clinical biomarker in the diagnosis and prognosis of the development of cachexia. Current knowledge suggests that ZAG mediates progressive weight loss through β-adrenergic signaling in adipocytes ...
Matthias Romauch
openalex   +5 more sources

Current status of neutron crystallography in structural biology

Biophysics and Physicobiology, 2022
Hydrogen atoms and hydration water molecules in proteins are essential for many biochemical processes, especially enzyme catalysis. Neutron crystallography enables direct observation of hydrogen atoms, and reveals molecular recognition through hydrogen ...
Fumiaki Kono, Kazuo Kurihara, Taro Tamada   +2 more
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Increased atherosclerotic plaque in AOC3 knock-out in ApoE−/− mice and characterization of AOC3 in atherosclerotic human coronary arteries

Frontiers in Cardiovascular Medicine, 2022
IntroductionAmine oxidase copper containing 3 (AOC3) displays adhesion between leukocytes and endothelial cells and enzymatic functions. Given its controversial role in atherogenesis, we proposed to investigate the involvement of AOC3 in the formation of
Anna Filip, Soraya Taleb, Rümeyza Bascetin, Mohammad Jahangiri, Matthieu Bardin, Cindy Lerognon, Bruno Fève, Patrick Lacolley, Sirpa Jalkanen, Nathalie Mercier   +9 more
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Biocatalytic Production of Aldehydes: Exploring the Potential of Lathyrus cicera Amine Oxidase

Biomolecules, 2021
Aldehydes are a class of carbonyl compounds widely used as intermediates in the pharmaceutical, cosmetic and food industries. To date, there are few fully enzymatic methods for synthesizing these highly reactive chemicals. In the present work, we explore
Elisa Di Fabio, Alessio Incocciati, Alberto Boffi, Alessandra Bonamore, Alberto Macone   +4 more
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Endothelial cell-derived SSAO can increase MLC20 phosphorylation in VSMCs

Open Life Sciences, 2021
Vascular hyporesponsiveness in the shock decompensation period is an important factor leading to death. Myosin light chain 20 (MLC20) is the main effector protein that regulates vascular reactivity.
Zhang Yuxing, Zhang Xiliang, Cao Zhen, Huang Yun, Zheng Yuexin, Yang Xiaodong   +5 more
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Effects of Chemical Structures Interacting with Amine Oxidases on Glucose, Lipid and Hydrogen Peroxide Handling by Human Adipocytes

Molecules, 2022
Benzylamine is a natural molecule present in food and edible plants, capable of activating hexose uptake and inhibiting lipolysis in human fat cells.
Christian Carpéné, Pénélope Viana, Zsuzsa Iffiú-Soltesz, Pál Tapolcsányi, Anna Ágota Földi, Péter Mátyus, Petra Dunkel   +6 more
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Copper-dependent amino oxidase 3 governs selection of metabolic fuels in adipocytes. [PDF]

PLoS Biology, 2018
Copper (Cu) has emerged as an important modifier of body lipid metabolism. However, how Cu contributes to the physiology of fat cells remains largely unknown.
Haojun Yang, Martina Ralle, Michael J Wolfgang, Neha Dhawan, Jason L Burkhead, Susana Rodriguez, Jack H Kaplan, G William Wong, Norman Haughey, Svetlana Lutsenko   +9 more
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Photodynamic Therapy of Novel Photosensitizer Ameliorates TNBS-Induced Ulcerative Colitis via Inhibition of AOC1

Frontiers in Pharmacology, 2021
Ulcerative colitis (UC), a chronic, nonspecific inflammatory bowel disease characterized by continuous and diffuse inflammatory changes in the colonic mucosa, requires novel treatment method.
Yumei Rong, Ge Hong, Na Zhu, Yang Liu, Yong Jiang, Tianjun Liu   +5 more
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Methylxanthines Inhibit Primary Amine Oxidase and Monoamine Oxidase Activities of Human Adipose Tissue

Medicines, 2020
Background: Methylxanthines including caffeine and theobromine are widely consumed compounds and were recently shown to interact with bovine copper-containing amine oxidase.
Wiem Haj Ahmed, Cécile Peiro, Jessica Fontaine, Barry J. Ryan, Gemma K. Kinsella, Jeff O’Sullivan, Jean-Louis Grolleau, Gary T.M. Henehan, Christian Carpéné   +8 more
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Prevalence of Genetic Diamine Oxidase (DAO) Deficiency in Female Patients with Fibromyalgia in Spain

Biomedicines, 2023
Diamine oxidase (DAO) is an enzyme that metabolizes intestinal histamine. Single nucleotide polymorphisms (SNPs) of the Amine Oxidase Copper Containing 1 (AOC1) gene can lead to low enzymatic activity or functionality in histamine metabolism.
Gülşah Okutan, Eva Ruiz Casares, Teresa Perucho Alcalde, Guerthy Melissa Sánchez Niño, Bruno F. Penadés, Ana Terrén Lora, Lorena Torrente Estríngana, Sara López Oliva, Ismael San Mauro Martín   +8 more
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