Results 41 to 50 of about 2,838,820 (225)

Exploring Molecular Oxygen Pathways in Hansenula polymorpha Copper-containing Amine Oxidase [PDF]

Journal of Biological Chemistry, 2007
The accessibility of large substrates to buried enzymatic active sites is dependent upon the utilization of proteinaceous channels. The necessity of these channels in the case of small substrates is questionable because diffusion through the protein matrix is often assumed.
Bryan J, Johnson, Jordi, Cohen, Richard W, Welford, Arwen R, Pearson, Klaus, Schulten, Judith P, Klinman, Carrie M, Wilmot   +6 more
openaire   +2 more sources

Enhancing Meat Quality Through Dietary Fiber: Insights Into the Gut Microbiota‐Derived Short‐Chain Fatty Acids‐Muscle Axis

Animal Research and One Health, EarlyView.
Dietary fiber (DF) modulates meat quality through the gut‐muscle axis by reshaping gut microbiota, improving intestinal integrity, reducing inflammation, and regulating muscle metabolism. These mechanisms influence muscle fiber characteristics and post‐mortem biochemistry, thereby enhancing tenderness, juiciness, color, flavor, and nutritional value of
Zeshan Zulfiqar, Muhammad Arslan Asif, Layla Al‐Mitib, Nabeela Ashiq, Haojie Wang, Yalei Cui, Boshuai Liu, Shucheng Huang, Yinghua Shi   +8 more
wiley   +1 more source

Interaction of the Lathyrogen Beta-Aminopropionitrile (BAPN) with a Copper-Containing Amine Oxidase.

Experimental Biology and Medicine, 1967
SummaryPig plasma amine oxidase, an enzyme thought to closely resemble the oxidase functional in collagen and elastin cross-linking, was assayed in the presence of a lathy rogen. BAPN was shown to inhibit enzyme activity competitively and reversibly and to form a complex with the active site of the enzyme.
R C, Page, E P, Benditt
openaire   +2 more sources

Plasma amine oxidase

, 2018
Copper-containing amine oxidases have been found in a wide range of eukaryotic cells of fungal, plant, and mammalian origin. 1 - 3 The Cu-AOs isolated from different tissues or phylae have many properties in common, but are distinctly different enzymes ...
Pettersson, G.,, Lund University.
core   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

BMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng, Yunfei Sha, Jiongyan Yang, Hongru Yang, Xiao Liang   +4 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model

Frontiers in Pharmacology
IntroductionMonoiodoacetate (MIA)-induced osteoarthritis (OA) is the most commonly used rodent model for testing anti-OA drug candidates. Herein, we investigated the effects of our patented multitarget drug candidate SZV-1287 (3-(4,5-diphenyl-1,3-oxazol ...
Ádám István Horváth, Ádám István Horváth, Kata Bölcskei, Nikolett Szentes, Nikolett Szentes, Nikolett Szentes, Éva Borbély, Éva Borbély, Valéria Tékus, Valéria Tékus, Valéria Tékus, Bálint Botz, Kitti Rusznák, Kitti Rusznák, Anett Futácsi, Anett Futácsi, Boldizsár Czéh, Boldizsár Czéh, Péter Mátyus, Zsuzsanna Helyes, Zsuzsanna Helyes, Zsuzsanna Helyes, Zsuzsanna Helyes, Zsuzsanna Helyes   +23 more
doaj   +1 more source

Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis

Arthritis Research & Therapy, 2017
Background Lysyl oxidase like-2 (LOXL2) is a copper-dependent amine oxidase. Our previous studies showed that LOXL2 is elevated during mouse fracture healing.
Weam Alshenibr, Mustafa M. Tashkandi, Saqer F. Alsaqer, Yazeed Alkheriji, Amelia Wise, Sadanand Fulzele, Pushkar Mehra, Mary B. Goldring, Louis C. Gerstenfeld, Manish V. Bais   +9 more
doaj   +1 more source

CD8+ T‐cells, CD86+ macrophages and TNF‐α signalling pathways are correlated with fetlock osteoarthritis in racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background There is emerging evidence for the role of the immune system in osteoarthritis (OA) pathophysiology; however, little is known about how immune cells and the synovial transcriptome are altered in naturally occurring equine OA. Objectives To evaluate synovial fluid (SF) and synovial membrane (SM) immune cell populations and the SM ...
E. J. Secor, E. N. Chow, M. Thomas, L. Johnson, A. Siefert, B. Wagner, J. B. Engiles, H. L. Reesink   +7 more
wiley   +1 more source

Catalytically active bovine serum amine oxidase bound to fluorescent and magnetically drivable nanoparticles

International Journal of Nanomedicine, 2012
Giulietta Sinigaglia1, Massimiliano Magro1, Giovanni Miotto1, Sara Cardillo1, Enzo Agostinelli2,3, Radek Zboril4, Eris Bidollari2,3, Fabio Vianello11Department of Biological Chemistry, University of Padua, Padua, Italy; 2Istituto Pasteur-Fondazione Cenci
Bidollari E, Zboril R, Agostinelli E, Cardillo S, Vianello F, Miotto G, Magro M, Sinigaglia G   +7 more
doaj