Results 41 to 50 of about 21,994 (249)

Cumulative effect of AOC1 gene variants on symptoms and pathological conditions in adult women with fibromyalgia: a pilot study

open access: yesFrontiers in Genetics, 2023
Introduction: The amine oxidase copper-containing 1 (AOC1) gene encodes for the diamine oxidase (DAO) enzyme. DAO is an enzyme that catabolizes some molecules, including histamine, and is the degradative enzyme in the polyamine catabolic pathway that is ...
Gülşah Okutan   +11 more
doaj   +1 more source

Cytochromes c550, c552, c1 in the electron transport network of Paracoccus denitrificans: redundant or subtly different in function? [PDF]

open access: yes, 2001
Paracoccus denitrificans strains with mutations in the genes encoding the cytochrome c550, c552, or c1 and in combinations of these genes were constructed, and their growth characteristics were determined.
Ludwig, B.   +5 more
core   +3 more sources

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

open access: yes, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna   +6 more
core   +2 more sources

Whole genome sequencing revealed genetic diversity, population structure, and selective signature of Panou Tibetan sheep

open access: yesBMC Genomics, 2023
Background The detection of selective traits in different populations can not only reveal current mechanisms of artificial selection for breeding, but also provide new insights into phenotypic variation in new varieties and the search for genes ...
Huibin Shi   +6 more
doaj   +1 more source

Interaction of plant amine oxidases with diaminoethers [PDF]

open access: yes, 2006
Polyamines are ubiquitous compounds, which are involved in crucial physiological events including cell growth and differentiation. The catabolic oxidative degradation of polyamines is catalyzed by quinoprotein copper-containing amine oxidases (CAOs ...
Floris, G   +6 more
core   +1 more source

A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase [PDF]

open access: yes, 2015
A new colorimetric method has been developed to screen transaminases using an inexpensive amine donor. The assay is sensitive, has a low level of background coloration, and can be used to identify and profile transaminase activities against aldehyde and ...
Baud, D   +4 more
core   +1 more source

The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products [PDF]

open access: yes, 2020
Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Bacinschi, Nicolae   +6 more
core   +2 more sources

Exploring the cellular and molecular differences between ovarian clear cell carcinoma and high-grade serous carcinoma using single-cell RNA sequencing and GEO gene expression signatures

open access: yesCell & Bioscience, 2023
The two most prevalent subtypes of epithelial ovarian carcinoma (EOC) are ovarian clear cell carcinoma (OCCC) and high-grade serous ovarian carcinoma (HGSC).
Dan Guo   +22 more
doaj   +1 more source

Ultrasound and microbubble-mediated delivery of miR-424-5p has a therapeutic effect in preeclampsia

open access: yesBiological Procedures Online, 2023
Objective To determine the influence of ultrasound/microbubble-mediated miR-424-5p delivery on trophoblast cells and the underlying mechanism. Methods Blood pressure and 24-h proteinuria of patients with preeclampsia (PE) were measured as well as the ...
Xudong Wang   +6 more
doaj   +1 more source

Proteome readjustments in the apoplastic space of Arabidopsis thaliana ggt1 mutant leaves exposed to UV-B radiation [PDF]

open access: yes, 2015
Ultraviolet-B radiation acts as an environmental stimulus, but in high doses it has detrimental effects on plant metabolism. Plasma membranes represent a major target for ROS generated by this harmful radiation.
ARRIGONI, GIORGIO   +8 more
core   +2 more sources

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