Results 1 to 10 of about 481,707 (338)

Blood Lead Levels in Children Living near Lead Smelting Zone: A Pilot Field Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Introduction: Children are most susceptible to Lead (Pb) toxicity. Exposure to lead in the environment still exists in various pockets of urban cities due to continued practices of using lead in jewellery making, paints, battery smelting and in ...
Kakali Roy   +6 more
doaj   +1 more source

Epigenetics of cancer drug resistance

open access: yesAcademia Biology, 2023
One of the major causes due to cancer-related death is metastasis. The major factors contributing to metastasis of cancer cells are epithelial–mesenchymal transition and cancer stem cells.
Sayandeep Mukherjee   +4 more
doaj   +1 more source

Familiarity Breeds Strategy: In Silico Untangling of the Molecular Complexity on Course of Autoimmune Liver Disease-to-Hepatocellular Carcinoma Transition Predicts Novel Transcriptional Signatures

open access: yesCells, 2021
Autoimmune liver diseases (AILD) often lead to transformation of the liver tissues into hepatocellular carcinoma (HCC). Considering the drawbacks of surgical procedures in such cases, need of successful non-invasive therapeutic strategies and treatment ...
Soumyadeep Mukherjee   +5 more
doaj   +1 more source

Lupeol synergizes with 5-fluorouracil to combat c-MET/EphA2 mediated chemoresistance in triple negative breast cancer

open access: yesiScience, 2023
Summary: Triple-negative breast cancer (TNBC) is the most elusive subtype of breast cancer that encounters treatment dilemmas owing to the paucity of druggable targets.
Debarpan Mitra   +10 more
doaj   +1 more source

In Silico Integration of Transcriptome and Interactome Predicts an ETP-ALL-Specific Transcriptional Footprint that Decodes its Developmental Propensity

open access: yesFrontiers in Cell and Developmental Biology, 2022
Early T precursor acute lymphoblastic leukemia (ETP-ALL) exhibits poor clinical outcomes and high relapse rates following conventional chemotherapeutic protocols.
Soumyadeep Mukherjee   +5 more
doaj   +1 more source

Imine- and Amine-Type Macrocycles Derived from Chiral Diamines and Aromatic Dialdehydes

open access: yesMolecules, 2022
The condensation of aromatic dialdehydes with chiral diamines, such as 1,2-trans-diaminocyclohexane, leads to various enantiopure or meso-type macrocyclic Schiff bases, including [2 + 2], [3 + 3], [4 + 4], [6 + 6] and [8 + 8] condensation products ...
Jerzy Lisowski
doaj   +1 more source

Acetylation of alcohols and amines catalyzed by onion peel ash under a base- and solvent-free condition [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2020
This manuscript describes a facile and environmentally benign protocol for the acetylation of various alcohol and amines catalyzed by onion peel ash under a base- and solvent-free condition. Various acetates were successfully prepared from the alcohols
Poh Wai Chia   +5 more
doaj   +1 more source

Simulation study of deep eutectic solvent-based biogas upgrading process integrated with single mixed refrigerant biomethane liquefaction [PDF]

open access: yesBiofuel Research Journal, 2020
Deep eutectic solvents (DESs) comprise ChCl/urea, in combination with water, have been considered in removing acid gases (CO2 and H2S) from biogas. The evaluation of DES for biogas upgrading at relatively high pressure (i.e., >8.0 bar) has not been ...
Junaid Haider   +5 more
doaj   +1 more source

Copper-catalyzed N-arylation of amines with aryliodonium ylides in water

open access: yesBeilstein Journal of Organic Chemistry, 2023
Copper sulfate catalyzed an efficient, inexpensive, and environment-friendly protocol that has been developed for N-arylation of amines with 1,3-cyclohexadione-derived aryliodonium ylides in water as a green solvent.
Kasturi U. Nabar   +2 more
doaj   +1 more source

Fluorinated Amine Stereotriads via Allene Amination [PDF]

open access: yesOrganic Letters, 2017
The incorporation of fluorine into organic scaffolds often improves the bioactivity of pharmaceutically relevant compounds. C-F/C-N/C-O stereotriad motifs are prevalent in antivirals, neuraminidase inhibitors, and modulators of androgen receptors, but are challenging to install.
Lu Liu   +4 more
openaire   +2 more sources

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