Results 21 to 30 of about 9,329,573 (350)
An Alternative Model of Amino Acid Replacement [PDF]
, 2004 The observed correlations between pairs of homologous protein sequences are typically explained in terms of a Markovian dynamic of amino acid substitution.
Altschul +27 more
core +3 more sources
ChemInform, 1998 AbstractFor Abstract see ChemInform Abstract in Full Text.
Mark G. Moloney +2 more
openaire +5 more sources
Frontiers in Immunology, 2020 Cardiovascular disease is the leading global health concern and responsible for more deaths worldwide than any other type of disorder. Atherosclerosis is a chronic inflammatory disease in the arterial wall, which underpins several types of cardiovascular
Bozidarka L. Zaric +8 more
doaj +1 more source
Animals, 2021 Mammary epithelial cells (MECs) in culture are a useful model for elucidating mammary gland metabolism and changes that occur under different nutrient disponibility. MECs were exposed to different treatments: 100% EAA for 8 h and 24 h restriction (R); 2%
Laura López-Diez +3 more
doaj +1 more source
Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer.
Cancer Cell, 2020 Metabolic pathways must be adapted to support cell processes required for transformation and cancer progression. Amino acid metabolism is deregulated in many cancers, with changes in branched-chain amino acid metabolism specifically affecting cancer cell
S. Sivanand, M. V. Vander Heiden
semanticscholar +1 more source
Amino acid requirements in horses [PDF]
Asian-Australasian Journal of Animal Sciences, 2020 Evaluating amino acid requirements, specifically threonine requirements, in horses will enable better feed formulation and result in economic production, improved animal health, and reduced environmental pollution.
Chan Hee Mok, Kristine L. Urschel
doaj +1 more source
Journal of Chemical Theory and Computation, 2019 Molecular dynamics (MD) simulations have become increasingly popular in studying the motions and functions of biomolecules. The accuracy of the simulation, however, is highly determined by the molecular mechanics (MM) force field (FF), a set of functions
Chuan Tian +10 more
semanticscholar +1 more source
Amino Acids and Inherited Amino Acid-Related Disorders [PDF]
Journal of Nutrition and Metabolism, 2018 Amino acids perform multiple essential physiological roles in humans, and accordingly, their importance to health has been the subject of extensive attention. In this special issue of the Journal of Nutrition and Metabolism, we focus on the various inborn errors of amino acid metabolism, their diagnostic challenges, new treatment approaches, and recent
Ina Knerr +4 more
doaj +3 more sources
Increased amino acid turnover and myofibrillar protein breakdown in advanced cancer are associated with muscle weakness and impaired physical function [PDF]
, 2018 Muscle wasting in cancer negatively affects physical function and quality of life. This study investigates amino acid metabolism and the association with muscle mass and function in patients with cancer.In 16 patients with advanced cancer undergoing ...
Deutz, Nicolaas E P +3 more
core +1 more source
The Regulatory Role of MeAIB in Protein Metabolism and the mTOR Signaling Pathway in Porcine Enterocytes. [PDF]
, 2018 Amino acid transporters play an important role in cell growth and metabolism. MeAIB, a transporter-selective substrate, often represses the adaptive regulation of sodium-coupled neutral amino acid transporter 2 (SNAT2), which may act as a receptor and ...
Ji, Peng +5 more
core +2 more sources