Results 131 to 140 of about 36,081 (264)

Diabetes risk and amino acid profiles: cross-sectional and prospective analyses of ethnicity, amino acids and diabetes in a South Asian and European cohort from the SABRE (Southall And Brent REvisited) Study.

, 2015
Aims/hypothesis: South Asian individuals have an increased risk of diabetes compared with Europeans that is unexplained by obesity and traditional or established metabolic measures.
Tillin, T, Hughes, AD, Godsland, IF, Würtz, P, McKeigue, PM, Forouhi, NG, Sattar, N, Eastwood, SV, Ala-Korpela, M, Chaturvedi, N, Wang, Q   +10 more
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

THE AMINO ACID COMPOSITION OF PHOSPHORYLASE

Journal of Biological Chemistry, 1951
S F, VELICK, L F, WICKS
openaire   +2 more sources

Modification of fetal plasma amino acid composition by placental amino acid exchangers in vitro

, 2007
Fetal growth is dependent on both the quantity and relative composition of amino acids delivered to the fetal circulation, and impaired placental amino acid supply is associated with restricted fetal growth.
Jackson, Alan A., Jackson, John M., Jane K. Cleal, Lewis, Rohan M., Sibley, Colin P.; id_orcid, Rohan M. Lewis, Alan A. Jackson, Brownbill, Paul, John M. Jackson, Hanson, Mark A., Keith M. Godfrey, Sibley, Colin P., Paul Brownbill, Brownbill, Paul; id_orcid, Mark A. Hanson, Cleal, Jane K., Colin P. Sibley, Godfrey, Keith M.   +17 more
core   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Amino acid composition (mole percent) of Hic31.

, 2015
Amino acid composition (mole percent) of Hic31.
Can Jin (685561), Shimei Zeng (781983), Shaojian Dong (781984), Xiaojun Liu (58952), Jiale Li (103362)   +4 more
core   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Effects of Different Lactic Acid Bacteria Fermentation on Nutritional Composition and Volatile Components of Birch Sap

Shipin gongye ke-ji
This study aimed to systematically evaluate the impact of lactic acid bacteria fermentation on the nutritional composition and flavor quality of birch sap, providing a scientific basis for the selection of strains for fermented birch sap.
Jiaying ZHENG, Yunuo LI, Gaoze LIANG, Hui WEN, Weidong ZHANG, Hongyuan ZHAO, Yanshen XU, Xiaonan WANG, Yujie FU, Baoqing ZHU   +9 more
doaj   +1 more source

The amino-acid composition of gramicidin [PDF]

Biochemical Journal, 1943
A H, Gordon, A J, Martin, R L, Synge
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source