Results 121 to 130 of about 36,081 (264)
Immobilization and mineralization of nitrogen in pasture soil
The results obtained from turf samples indicate that growing plants are mainly responsible for the accumulation of soil organic nitrogenous compounds.
Huntjens, J.L.M.
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Since its arrival in New Zealand the clover root weevil (Sitona lepidus (syn. flavescens) (Coleoptera: Curculionidae) (CRW) has caused serious damage to New Zealand’s agricultural sector. The introduction of the biocontrol agent, Microctonus aethiopoides
Brown, Jolene Mary
core
Genome-wide analysis of coding DNA and amino acid variation in Saccharomyces cerevisiae
The possible causes of variation on amino acid composition in the yeast Saccharomyces cerevisiae were investigated genome-wide. The results indicated that: (a) the base composition of coding DNA and amino acid composition was similar among all the ...
Wang, Jinxia +4 more
core +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Primary structure and glycosylation of the S-layer protein of Haloferax volcanii
The outer surface of the archaebacterium Haloferax volcanii (formerly named Halobacterium volcanii) is covered with a hexagonally packed surface (S) layer. The gene coding for the S-layer protein was cloned and sequenced.
Sumper, Manfred +3 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Evaluation on Amino Acid Composition and Nutritional Value from Different Walnut Varieties
In this study, nine varieties of walnut nuts were used as test materials to determine the amino acid composition and content, calculate their nutritional value scores, and conduct principal component analysis and cluster analysis to comprehensively ...
Yuanru HAO, Ruidie CHEN, Meizhi ZHAI
doaj +1 more source
THE AMINO ACID COMPOSITION OF RIBONUCLEASE
C H, HIRS, W H, STEIN, S, MOORE
openaire +2 more sources

